Warm-Up DNA Mutations - Edgenuity Inc.

Warm-Up

DNA Mutations

Lesson Objectives

By the end of this lesson, you should be able to:

? Describe common types of DNA

.

? Explain the effects of DNA mutations on the

of living organisms.

? Analyze the effect of harmful

Science Practice: Discriminate between scientific

factors on DNA.

that are

socially accepted but not scientifically based.

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Warm-Up

W

2K

DNA Mutations

Words to Know

Fill in this table as you work through the lesson. You may also use the glossary to

help you.

a mutation in which a single base is added to or

deleted from DNA

a mutation that causes a change in a single base pair

in DNA

an agent that causes a mutation in DNA

the replacement of one base with another in the DNA

sequence, resulting in a point mutation

a change in the DNA sequence that is caused by the

elimination of one or more base pairs and that results

in a frameshift mutation

a change in the DNA sequence that is caused by the

addition of one or more extra base pairs and results

in a frameshift mutation

a permanent change in the DNA sequence of a gene

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Instruction

DNA Mutations

Slide

1

Lesson

Question

2

DNA

? DNA is like a sentence made of

-letter words.

? If the sentence is altered, the

of the sentence is permanently

.

? The DNA is read in segments of three

? Each of the three sequential bases is a

.

.

Changes in DNA

: A permanent change in the DNA sequence of a gene

If the DNA sequence is

, then the

is permanently

changed.

? This may or may not change the

that is coded for by that

gene.

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Instruction

DNA Mutations

Slide

2

DNA Mutations

mutation: A mutation that causes a change in a single base pair

in DNA

Circle the base that has changed in the mutated DNA sequence.

Original

Codon 1

ATA isoleucine

Codon 2

TCA serine

Codon 3

CTG leucine

Codon 4

TGC cysteine

Codon 3

CTG leucine

Codon 4

TGC cysteine

Muted

x`

Codon 2

Codon 1

ATA isoleucine ACA threonine

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Instruction

DNA Mutations

Slide

2

Point Mutations

: The

of one base with another in the

DNA sequence; results in a point mutation

Circle the mutation in the second DNA sequence.

x`

Point Mutations: Three Types

mutation

?

amino acid

mutation

? Creates

codon

x`

mutation

? Changes codon; amino acid is

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