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The doses of dabigatran were actually adjusted to obtain a trough plasma level of 50 nanograms per milliliter. And warfarin was adjusted to normal INRs of 2 to 3 or 2.5 to 3.5, depending on thromboembolic risks and the type of valve. And as I mentioned, the study was terminated prematurely after enrollment of 252 patients because of excess ... ................
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