Ramipril

Mechanism of Action. The ACE inhibitors: 1. Inhibit the action of ACE: They are highly specific competitive inhibitors of angiotensin I converting enzyme, (ACE), the enzyme responsible for the conversion of angiotensin I to angiotensin II. 2. Inhibit the breakdown of bradykinin, (see Appendix 1) Pharmacodynamics. In single dose studies, doses of 5-20 mg of ramipril lowered blood pressure ... ................
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