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Medications for ADHD
Stimulant Medications-First Line Treatments
Generic Class (Brand Name) Daily Dosage Duration of Behavioral Prescribing Schedule
Schedule Effects (hours)
Methylphenidate
Short-acting BID to TID 3-5 2.5-20 mg BID to TID
(Ritalin, Methylin,
Focalin)
Intermediate-acting Once daily (QD) 3-8 10-40 mg QD or 40 mg
(Ritalin SR, Metadate ER, to BID in the morning and
Methylin ER, Ritalin LA) 20 mg early afternoon
Long-acting
(Concerta, Metadate CD) QD 10-12 18-72 mg QD
Daytrana (transdermal QD 9 10-30 mg QD
patch)
Quillivant ER (5mg/ml) QD 12 20-60 mg QD
Amphetamines
Short-acting BID to TID 4-6 5-15 mg BID or 5-10
(Dexedrine, Dextrostat) mg TID
Intermediate-acting QD to BID 6-8 5-30 mg QD or 5-15
(Adderall, Dexedrine BID
Spansules)
Long-acting QD 10-12 10-40 mg QD
(Adderall XR)
(Lisdexamfetamine) QD 12 30-70 mg QD
Non-Stimulant Medications-Second Line Treatments
Generic Class (Brand Name) Daily Dosage Schedule Prescribing Schedule
Tricyclic Antidepressants BIB toTID 2-5 mg/kg/day
Imipramine, desipramine,
nortriptyline
Norepinepherine reuptake inhibitor
Atomoxetine QD to BID Start at 0.5 mg/kg/day;
After 4 days between
1.2-1.4 mg/kg/day
Amino-ketone antidepressant
Bupropion
(Wellbutrin) QD to TID 50-100 mg TID
(Wellbutrin SR) BID 100-150 mg BID
(Wellbutrin XL) QD 300 mg
Alpha-2 agonists
Clonidine
Tablet BID to QID 0.05-0.4 mg/day
Transdermal patch Q 3 to 7 days 0.1-0.3 mg delivered/day
Long acting (Kapvay) BID 0.1-0.2 mg BID
Guanfacine
Tablet QD to BID 0.5-4.0 mg/day
Intuniv (24 hr duration) QD 1-4 mg/day
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