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Time Allotted (min)ActivityMaterials Needed1Goal – Been There, Doing That, Will Do15Review Cell Surface Proteins via “What’s In the Box?” to transition to…Sand, cheez-its, bowl of candy, Gatorade bottle filled with thumb tacks, Jell-O15Blood Type Punnett Squares Examples & Blood Typing/Transfusion Notes Handouts (attached)10Amoeba Sisters – Blood TypesYouTube Video10Blood Typing Crime Scene ProblemsHandout (attached)5Prediction – how are inheritance and evolution linked?noneThink Outside the Box! AnalogyTo our past (cell types and cell surface proteins):The REMOVED objects from the box are like ___________________________. ___________________________.The people removing objects from the box are like ___________________________. ___________________________.Did anything get removed from the box that should have been left in the box? _____.If so, what was it? ___________________. So, we removed something that should have been left in the box… What could you compare this to? _____________________.To our present (red blood cell types and blood typing):The REMOVED objects from the box are like ___________________________. ___________________________.The people removing objects from the box are like ___________________________. ___________________________. Polygenic Inheritance - 5th Type of Inheritance!!Poly = Genic = So, Polygenic Inheritance is – Great examples – Blood Type: As you should know from yesterday…There are _________________ major blood phenotypes in humans!They are: NEW: There are ________________ major blood GENOtypes in humans!Blood PhenotypesPossible Blood GenotypesSo, how do you end up with your blood phenotype??And… how do you end up with your blood genotype?? Complete the Punnett Squares below.Blood Transfusion & Blood ChemistryFrom yesterday, you should know that receiving the wrong blood type can be deadly. Let’s look at the reasons why…If you have type A blood, you also have ______________________ to type ________.If you have type B blood, you also have ______________________ to type ________.If you have type AB blood, you have __________ antibodies (to blood types)!!If you have type AB blood, you also have __________________________ to __________!!So… if you get the wrong blood type in a transfusion…the antibodies grab a hold of the antigen and the clump together in a process called ______________________. Why does it do this?In 2015, do we need to worry about this? Not so much, but we definitely do need to worry about our blood interaction during pregnancy!DAD MOMLet’s look at the baby here. Will mom’s immune system attack the blood of the baby? ______ because:But… there is something called rh factor. rh is a __________________ which your immune system WILL attack if it thinks it is foreign.So, if mom is rh- and the baby is rh+, that is a problem. Thankfully it is easy to fix, but you and the doctors need to know when it comes time to have a baby!Think Outside the Box! AnalogyTo our past (cell types and cell surface proteins):The REMOVED objects from the box are like _________________________. _________________________.The people removing objects from the box are like ___________________. ___________________.Did anything get removed from the box that should have been left in the box? _____.If so, what was it? ___________________. So, we removed something that should have been left in the box… What could you compare this to? _____________________.To our present (red blood cell types and blood typing):The REMOVED objects from the box are like _______________________. _______________________.The people removing objects from the box are like ___________________. ___________________. ................
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