Cpb-us-w2.wpmucdn.com



|Penicillins |Penicillin |IV/PO |G+ only, All GAS/GBS, syphilis, oral anaerobes (but not gut), |exudative pharyngitis, erysipelias |

| | | |clostridium | |

| |Nafcillin (IV)/oxacillin(po)/dicloxacillin(po) |IV/PO |G+ only DOC MSSA, can use for strep, (no MRSA), no G neg |Cellulitis, s. aureus cutaneous abscess |

| | | | | |

| |B lactamase resistant penicillins | | | |

| |Ampicillin(IV)/amoxicillin(po) |IV/PO |G+ and some G- DOC for enterococcus, strep like pen, no staph, only a |1st line acute otitis media, acute sinusitis, neonatoal meningitis |

| | | |little G neg (some H.flu, some e. coli), listeria |with gentamicin |

| |aminopenicillins | | | |

| |Piperacillin |IV |Like amp + G-, so good for strep, enterococcus and G neg incl | |

| | | |pseudomonas + anaerobes, but NO MSSA | |

|Pen + B lactamase inhib (adds |Amp/sulbactam (unasyn) IV |IV |Like amp + MSSA and anaerobes, NO MRSA, H.flu, most anaerobes, listeria|Failed tx of otitis media |

|MSSA) | | | | |

| |Amox/clavulanate (augmentin) po |PO | | |

| |Pipercillin/tazobactam (zosyn) |IV |All except MRSA, including pseudomonas and enteric G- | |

| | | | | |

| |Ticarcillin/tazo? (Timentin) | | | |

|Cephalosporin |All | |No enterococci, NO MRSA, no listeria | |

| |1st gen: Cefazolin (ancef) IV |IV |Staph and strep in pen allergic pt (10% cross react), G pos, few G neg | |

| | | |(ex ecoli), few anaerobes | |

| |Cephalexin (Keflex) PO |PO | | |

| |2nd gen: Cefoxitan (Mefoxin) iv |IV |Above + H.flu, more G neg, anaerobes |gut surg prophylaxis, otitis failed augmentin, |

| | |PO | | |

| |Cefpodoxime (Vantin) iv | | | |

| | | | | |

| |Cefuroxime (Ceftin) po/iv | | | |

| |3rd gen: Ceftriaxone (Rocephin) im/iv |IV |A lot of G neg (no pseudomonas), not as good for staph as first and |Comm acquired Meningitis in all except neonates – crosses BBB, also |

| | | |second gen, still good for GAS/GBS and s.pneumo |for pyelo in kids and adults |

| |Cefotaxime (Omnicef) po | | |Rocephin, bad in neonates – biliary sludging/Ca++ precipitation, can|

| | | | |use cefotaxime |

| | | | |Omnicef – otitis failed augmentin |

| |4th gen: Cefipime |IV |G pos, most G neg, incl pseudomonas, limited anaerobes, no enterococcus| |

| | | | | |

| |Ceftazidime | | | |

| | | |Nosocomial meningitis, pseudomonas | |

|Carbapenem |Meropenem (kids) |IV |Gram pos incl. entero, gram neg, pseudomonas, anaerobes, ESBL gram neg,|Imipenem – decreases seizure threshold |

| | | |NO MRSA, no acinetobacter | |

| |Imipenem (Primaxin) | | | |

| | |IV |Like imipenem but no pseudomonas |Q day, no CNS penetration |

| |Ertapenem (Invanz) | | | |

|Macrolides |Erythromycin |IV/PO |Gram pos, some anaerobes, atypicals, NO gram neg |Can cause pyloric stenosis so CI in neonates |

| |Azithromycin |IV/PO |Above + H.flu, MAC tx, prophylaxis, more G- than erythro |Pretty good resp drug, Pen allergic for strep throat, otitis media, |

| | | | |DOC outpatient community acquired pneumonia in teenagers/adults, |

| |Clarithromycin (Biaxin) | | |pertussis |

| |Tetracycline |PO |Some gram neg, gram pos, SOME MRSA, some anaerobes, atypicals - Kill |Use if MRSA or e. coli known to be sensitive b/c cheap |

| | | |some of everything |Relative CI in kids ................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download