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Name: Date: Period:

14.3D Blood Typing

DIRECTIONS: Part A - go to the website:



Click on: This icon (

READ through the passages to answer the questions below.

The discovery of blood groups

1. Many patients have died and it was not until _________, when Austrian Karl Landstreiner discovered human blood groups, that blood transfusions became safer.

Mixing blood from two individuals can lead to _____________________________________. This can have fatal consequences.

What is blood made up of?

2. An adult human has about _____________ of blood circulating in the body. Among other things, blood ____________________________ to various parts of the body.

Blood consists of several types of cells floating around in a fluid called plasma.

The red blood cells contain _________________________________________________. Red blood cells transport oxygen to, and remove carbon dioxide from, the body tissues.

The white blood cells _________________________________.

The platelets help ______________________, if you get a wound for example.

The plasma contains salts and various kinds of proteins.

What are the different blood groups?

3. The differences in human blood are due to the _____________________________________

of certain protein molecules called ______________________________________________ . The antigens are located on the surface of the red blood cells and the antibodies are in the blood plasma. The blood group you belong to depends on what you have inherited from your parents.

There are more than _____ genetically determined blood group systems known today, but the ABO and Rh systems are the most important ones used for blood transfusions. _______

____________________________________________. Mixing incompatible blood groups leads to blood clumping or agglutination, which is dangerous for individuals.

Nobel Laureate Karl Landsteiner was involved in the discovery of both the ABO and Rh blood groups.

ABO blood grouping system

4. According to the ABO blood group system there are __________ different kinds of blood groups: ______________________ .

Blood group A

If you belong to the blood group A, you have __________________ on the surface of your red blood cells and __________________ in your blood plasma.

Blood group B

If you belong to the blood group B, you have __________________ on the surface of your red blood cells and __________________ in your blood plasma.

Blood group AB

If you belong to the blood group AB, you have __________________________ on the surface of your red blood cells & __________________________ at all in your blood.

Blood group O

If you belong to the blood group O (null), you have __________________________ on the surface of your red blood cells but you have __________________________ in your blood plasma.

Rh factor blood grouping system

5. Many people also have a so called ___________________ on the red blood cell’s surface. This is also an antigen and those who have it are called _________ . Those who don’t have it are called ________ . A person with Rh- blood does not have Rh antibodies naturally in the blood plasma. But a person with Rh- blood can develop Rh antibodies in the blood plasma if he or she receives blood from a person with Rh+, whose Rh antigens can trigger the production of Rh antibodies. A person with Rh+ blood can receive blood from a person with Rh- blood without any problems.

Rh+ cannot donate to an Rh- person. Knowing this, place an “X” on the appropriate line.

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Blood typing – how do you find out to which blood group someone belongs?

Watch the “Click GO for agglutination” animation.

Scroll to the bottom of the page and click “Play the Blood Typing game”.

Click “Play” located under the clock.

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Click any of the 3 patients.

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6. Determine the blood types that can be received by each patient. To do this, click the syringe, draw blood from patient’s arm, check for clumping in the blood types & Rh factor.

Complete the table below.

|Patient |Blood type they can receive |

|Woman – Red Hair | |

|Man – Elderly | |

|Man – Pink Mohawk | |

All done! Party!

If you have time and you

would like to, play the NEW

version of the game.

7. Person on the left is a donor. Determine if the two people on the right can receive blood from this particular donor. The baby on the right is the child from the person in the middle. Write yes or no showing who can receive blood from the donor on the left in both situations.

Donor Recipient 1 Recipient 2

[pic] [pic]

Rh - Rh + Rh -

Receive from donor? _______ Receive from donor? _______

8. DRAW arrows to complete the diagram below.

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Right here!

(old version)

Right here!

Any of these to start.

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