FFR - European Society of Cardiology
FFR
Hyperemia and Standardization
Bernard De Bruyne
Cardiovascular Center Aalst
Belgium
Hyperemic Stimuli
Why ?
How ?
FAQ !
Bernard De Bruyne, MD, PhD
Cardiovascular Center Aalst
OLV-Clinic Aalst, Belgium
Why?
1. General concept of stress test (as opposed to ¡°rest test¡±)
2. Standardized measurements (as opposed to ¡°moving target¡±)
3. Rest vs hyperemia = window towards the microvasculature
4. All clinical outcome data are based on hyperemic data (FFR)
General concept of stress test
Mild Aortic Stenosis
Rest
CO 4.8 L/min
Dobutamine
40 ?g/kg/min
CO 8.1 L/min
P = 17 mm Hg
P = 21 mm Hg
General concept of stress test
Diabetes
Oral Glucose Tolerance Test:
75 g of sugar to be drunk within 5 minutes
Normal
Mg/dL
200
200
180
180
160
160
140
140
120
120
100
100
80
80
60
60
40
40
20
20
0
0
Fasting
2 hours
4 Hours
Diabetes
Mg/dL
Fasting
2 hours
4 Hours
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