Breast Cancer
Chemotherapy: Topotecan 0.75 mg/m2/day i.v. infusion over 30 minutes Days 1-3 Cisplatin 50 mg/m2 i.v. infusion over 2 hours Day 1 Urine should be maintained above 100mL/hr throughout treatment. If output falls below 400mL in any 4 hour period, then give furosemide 20mg i.v. repeated as necessary .Alternatively mannitol may be used. ................
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