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The Bronx High School of Science Biology DepartmentDr. J. Donahue, Principal Dr. Allison Davis, APAP Biology Syllabus, 2019-2020Textbook: Campbell Biology, 10th edition (2014), Reece et al.Lab Manual: AP Biology Investigative Labs: An Inquiry-Based Approach, Student ManualAdditional Resources:AP Biology Course and Exam Description, Effective Fall 2019, .pdf available at apcentral.Suggested review books: Test Prep Series for AP Biology (2014) by Holtzclaw & Holtzclaw or CliffsNotes AP Biology, 5th editionThe 4 Big IdeasThe process of evolution drives the diversity and unity of life.Biological systems utilize free energy and molecular building blocks to grow, to reproduce, and to maintain dynamic homeostasis.Living systems store, retrieve, transmit, and respond to information essential to life processes.Biological systems interact, and these systems and their interactions possess complex properties.The 7 Science PracticesThe student can use representations and models to communicate scientific phenomena and solve scientific problems.The student can use mathematics appropriately.The student can engage in scientific questioning to extend thinking or to guide investigations within the context of the AP course.The student can plan and implement data collection strategies appropriate to a particular scientific question.The student can perform data analysis and evaluation of evidence.The student can work with scientific explanations and theories.The student is able to connect and relate knowledge across various scales, concepts and representations in and across domains.Course Grading RubricExams and Quizzes50%Laboratory Assignments20%Homework10%Midyear Exam & Final Exam/Projects10%Class & Lab Participation10% *Daily standing homework assignment: Review class notes. Read corresponding materials in textbook, lab manual, review book.**All dates on the syllabus are tentative and may be changed as necessary.WeekTopicLab ActivitiesText Ch.Sep 2-6xMTWSchool beginsHow do we define life?Life characteristics and processesReview of prerequisite knowledge1, 19Sep 9-13Evolution describes the diversity and the unity of lifeDarwin’s theory of descent with modificationEvidence for evolution by natural selectionVirtual Lab: Introduction to Gene Expression22, 25Sep 16-20Phylogenetic trees show evolutionary relationshipsSurvey of classification (DKPCOFGS)UNIT EXAM 12628.11Sep 23-27Emergent properties and the hierarchy of life: From atoms to the biosphere and the “Powers of 10”Ecology: Interactions of organisms with each other and their environmentBiotic and abiotic factorsEcosystems and biomes152, 53Sep 30 - Oct 4xMTRosh HashanahPopulation ecologyCommunity ecologyNatural selection of behavioral and life strategiesMathematical calculations in ecology 54, 5551Oct 7-11xWYom Kippur How do we do science? Experimental designData analysisLab Manual: Introduction; CH1 What is Inquiry?; CH2 Written, Verbal, & Graphic Information; CH3 Quantitative Reasoning; Appendix A & B Investigation 12: Animal Behavior Lab (Big Idea 4)1Oct 14-18xMColumbus Dayx?WPSATStatistical analysis: measures of central tendency (mean, median, mode); measures of variability (VAR, SD, SEM, CI); statistical significance (chi-square, p-value)UNIT EXAM 2Statistics LabOct 21-25Chemistry of lifeAtoms to molecules Emergent properties of waterCohesion and adhesionPlant structureTranspiration-cohesion-tension theorySpecific heat capacityHeat of vaporizationVersatility as solventpH and buffers 2,336Oct 28 - Nov 1Carbon and structure and function of organic molecules Dehydration synthesis and hydrolysisStructure and function of large biological molecules: carbohydrates, lipids, nucleic acids, proteinsUNIT EXAM 34, 516Nov 4-8xTElection Day? xFPT conferencesIntroduction to MetabolismThermodynamicsChemical reactions8Nov 11-15xMVeterans DayEnzymes as organic catalysts Regulation of enzyme activityUNIT EXAM 4Investigation 13: Enzyme Activity (Big Idea 4)Nov 18-22Cell structure & functionHow we study cellsoverview of prokaryotes vs. eukaryotesUsing the microscope to view cells: observations of select organisms6, 728.1Nov 25-29xRFThanksgivingOrigin of life: early earth, prokaryotes, eukaryotesCell membrane structure and functionMaking proto-cells in the lab (Big Idea 1)256,7Dec 2-6Transport across cell membraneLimits to cell sizeInvestigation 4: Diffusion & Osmosis (Big Idea 2)6,7Dec 9-13Subcellular organization, organellesExtracellular structuresUNIT EXAM 51131Dec 16-20Cell communicationSignal transduction pathwaysApoptosisQuorum sensing in bacteriaMating in fungi11314529, 30Dec 23-27xTWRFWINTER RECESS Dec 24 – Jan 1 (no classes)Dec 30-Jan 3xMTWNew Year’s DayHomeostasisNervous system: nervous system organization, reflex arc, nerve cell communicationMusculoskeletal system: neuromuscular junction, muscle contraction4048, 49, 50Jan 6-10Endocrine system: mammalian fight or flight response, blood glucose control, thermoregulation, circadian rhythmPlants: adaptations, life cycle, hormones, response to environmentUNIT EXAM 64535, 38, 39Jan 13-17xFMidterm ExamsMaterial cycles and energy flow in ecosystemsCarbon and oxygen cyclesPrimary, gross and net productivity Cellular respiration and fermentationThe ATP cycleRedox reactionsGlycolysis 559Jan 20-24xMMLK DayxTWRFUNIFORM MIDTERM EXAMS Jan 17-24 (no classes)AP BIOLOGY MIDTERM EXAM (DATE TBA)Jan 27-31xMChancellor’s DayOxidation of pyruvate to acetyl-CoACitric Acid CycleOxidative Phosphorylation FermentationRegulation of cellular respiration rate9Feb 3-7PhotosynthesisPlant leaf structureLight-dependent reactions transform light energy into chemical energy (ATP + NADPH)Synthesis of carbohydrates via the Calvin cycleInvestigation 5: Photosynthesis (Big Idea 2)10Feb 10-14Acquisition of resources for photosynthesisPhysical and biochemical adaptations in plantsPrimary productivityEutrophicationUNIT EXAM 73655Feb 17-21xMTWRFMID WINTER RECESS (no classes)Feb 24-28The cell cycleMitosis and cytokinesisBinary fission in prokaryotesCell cycle regulationDNA integrityCancerGross chromosomal abnormalitiesGenomes and their evolutionSources of genetic variationInvestigation 7: Cell Division- Karyotyping Lab (Big Idea 3)12Mar 2-6Meiosis and sexual life cyclesReduction from 2n to n Sources of genetic variationEvolutionary advantages to sexual reproductionUNIT EXAM 813Mar 9-13Classical geneticsMendelian inheritance patternsExtensions of Mendelian geneticsPhysical basis of hereditary factors Chromosomal basis of sex1415Mar 16-20? xFPTCGenetic recombination and linkage analysisOrganelle genesMobile genetic elementsPedigree analysisGenetics of Corn and Chi-square Probability (Big Idea 3)15Mar 23-27Mechanisms of evolutionHardy-Weinberg theorem and microevolution Speciation and macroevolution Role of mass extinctionsHuman impact on biodiversity and the environmentUNIT EXAM 9Investigation 2: Mathematical Modeling- Hardy-Weinberg (Big Idea 1)23, 24, 25, 2156Mar 30 - Apr 3Molecular geneticsDNA is the hereditary materialDNA replication and maintenance of DNA integrityGene expression: From gene to proteinTranscriptionTranslation1617Apr 5-10xRFRegulation of gene expressionInducible and repressible operons in prokaryotesRegulation of gene expression in eukaryotesRole of gene expression in developmentConsequences of mutations that affect gene expression1847Apr 13-17xMTWRF SPRING RECESS Apr 9-17 (no classes)Apr 20-24Genetics of VirusesViral structure and functionViral reproductive cycles Genetics of ProkaryotesSurvey of Bacteria and ArchaeaTransformation, transduction, and conjugation1927Apr 27 - May 1BiotechnologyCloning and recombinant DNA technologyDNA fingerprintingInvestigation 8: Biotechnology- Bacterial Transformation (Big Idea 3)20May 4-8Genetically Modified OrganismsEthical considerationsUNIT EXAM 10Investigation 9: Biotechnology- Restriction Enzyme Analysis of DNA (Big Idea 3)May 11-15AP Exam WeekxM AP Bio Exam**AP BIOLOGY EXAM, MONDAY, MAY 11 AT 8:00 AM**Animal Physiology (systems not yet covered)Immune systemDigestive systemIntroduction of Final Exam Projects404341May 18-22Circulation and gas exchangeOsmoregulation and excretion ReproductionUNIT EXAM 11424446May 25-29xMMemorial DayAnatomy & PhysiologyFinal Exam Projects Fetal Pig DissectionJun 1-5xTRRegents ExamAnniversary Day Anatomy & PhysiologyFinal Exam ProjectsFetal Pig DissectionJun 8-12Anatomy & PhysiologyFinal Exam ProjectsFetal Pig DissectionJun 15-19xWRFLast day of classes, Tuesday, June 16Final Exam Project Presentations ................
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