Chemical Control of Grafted Human PSC-Derived Neurons in a ...
of dopamine (DA) neurons in the midbrain and insufficient DA release in the striatum, transplantation of human fetal ... Gi, and Gs). These receptors can be activated by pharma-cologically inert compounds such as clozapine-N-oxide (CNO), ... the graft-repaired circuit, and hence the therapeutic outcomes, ... ................
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