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Supplementary Appendix 1. LIBERTY 360 Participating InstitutionsLIBERTY 360 Participating InstitutionsMetro Health Hospital, Wyoming, MICoastal Vascular and Interventional, Pensacola, FLMid-Michigan Heart and Vascular Center, P.C., Mt. Pleasant, MIRex Hospital, Raleigh, NCSt. Luke's Medical Center, Phoenix, AZGotham Cardiovascular Research, PC, New York, NYMission Research Institute, New Braunfels, TXArkansas Heart Hospital Clinic, Little Rock, AREl Paso Cardiology Associates, El Paso, TXMercy Gilbert Medical Center, Chandler, AZFirst Coast Cardiovascular Institute, Jacksonville, FLSt. John Hospital and Medical Center, Detroit, MIDuke University Hospital, Lumberton, NCHouston Methodist Sugar Land Hospital, Sugar Land, TXKentuckyOne Health, Lexington, KY Premier Surgical Associates, Knoxville, TNSan Antonio Endovascular & Heart Institute, San Antonio, TXMidwest Cardiovascular Research Foundation, Davenport, IARiverside Methodist Hospital/Ohio Health, Columbus, OHCardiovascular Associates of East Texas, Tyler, TXMemorial Hospital of Carbondale, Carbondale, ILColorado Heart and Vascular, Lakewood, COUniversity Surgical Associates, Chattanooga, TNColumbia University Medical Center, New York, NYVA Eastern Colorado Health Care System-Denver VAMC, Denver, COMichigan Outpatient Vascular Institute, Dearborn, MICardiothoracic and Vascular Surgeons/CTVS, Austin, TXShady Grove Adventist Hospital, Rockville, MDLester E. Cox Medical Centers, Springfield, MOBaptist Memorial Hospital – DeSoto, Southaven, MSWellmont CVA Heart Institute, Kingsport, TNClearwater Cardiovascular & Interventional Consultants, Clearwater, FLBaptist Cardiac and Vascular Institute, Miami, FLProvidence Health Center, Waco, TXThe Heart Institute at Largo, Largo, FLHartford Hospital, Hartford, CTYale-New Haven Hospital, New Haven, CTSaint Luke's Hospital, Kansas City, MOSanford Research, Sioux Falls, SDMount Sinai Medical Center Heart Institute – Miami, Miami Beach, FLRadiology and Imaging Specialists of Lakeland, P.A., Lakeland, FLUniversity of Texas Medical Branch at Galveston, Galveston, TXFlorida Hospital Tampa, Pepin Heart Institute, Tampa, FLFlorida Hospital, Orlando, FLSt. John’s Hospital Springfield, Springfield, ILMetropolitan Heart Institute, Coon Rapids, MNHouston Methodist Hospital Research Institute, Houston, TXSt. John Health System, Tulsa, OKChicago Vascular Clinic, Schaumburg, ILPhoenix Heart Cardiovascular Lab, Glendale, AZCedars-Sinai Heart Institute, Los Angeles, CASupplementary Table 1. Procedural parameters and angiographic complications (Core Lab reported).Rutherford 5-6Lesion location within legN=558ATK only132 (23.7)ATK and BTK62 (11.1)BTK only363 (65.1)Unknown1 (0.2)Target lesion lengthN=524<40 mm141 (26.9)40 – 99 mm139 (26.5)≥100 mm244 (46.6)Chronic total occlusions233/547 (42.6) TASC lesion typeN=536A253 (47.2)B103 (19.2)C94 (17.5)D86 (16.0)Predominant calcified plaque morphology314/525 (59.8)PARC degree of calcificationN=282Focal35 (12.4)Mild39 (13.8)Moderate70 (24.8)Severe138 (48.9)Minimal lumen diameter (mm)Pre-procedure0.5 ± 0.7 0.3 [0.0, 0.9] (N=545)Post-procedure final 2.2 ± 1.2 2.0 [1.4, 3.0] (N=531)Target lesion % stenosisPre-procedure 83.5 ± 18.489.0 [70.0, 100.0] (N=547)Post-procedure final33.9 ± 21.0 31.0 [21.0, 42.0] (N=531)Lesion success 429/533 (80.5)<50% residual stenosis for target lesion 468/535 (87.5)Severe angiographic complications 51/552 (9.2)Severe dissection 16/557 (2.9)Perforation6/557 (1.1)Abrupt closure6/557 (1.1)Distal embolization25/552 (4.5)Data provided as mean ± standard deviation/median [IQR] or number (percentage) as appropriate.ATK = above-the-knee; BTK = below-the-knee; PARC = Peripheral Academic Research Consortium; TASC = Trans-Atlantic Inter-Society Consensus.Supplementary Figure 1. Change in Rutherford classification (RC) over time. Percentage of patients within each Rutherford classification over time as recorded at each follow-up visit. Patient number in parenthesis at each time point. ................
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