US Flu VE Network and US Hospitalized Adult Influenza Vaccine ...
National Center for Immunization & Respiratory Diseases
Influenza Vaccine Effectiveness, 2016-17
US Flu VE Network &
US Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN)
Jill Ferdinands, PhD
CDC Influenza Division Meeting of the Advisory Committee on Immunization Practices (ACIP) June 21, 2017
Objectives
Review end-of-season estimates of 2016-17 influenza vaccine effectiveness (VE) from US Flu VE Network (outpatient flu, all ages)
Introduce US Hospitalized Adult Influenza Vaccine Effectiveness Network (HAIVEN) (inpatient flu, adults) and present preliminary 2016-17 VE estimates
2
UUSUS Flu VE Network VE Estiates, 2016-17
OUTPATIENT ALL AGES
US Flu VE Networks 2016-2017 Outpatients All Ages
3
US Flu VE Network and principal investigators
Kaiser Permanente Washington Health Research Institute
Mike Jackson Lisa Jackson
Marshfield Clinic Research Institute
Ed Belongia Huong McLean University of Michigan
Arnold Monto
Emily Martin
Baylor Scott & White Health Manju Gaglani
University of Pittsburgh Rick Zimmerman Tricia Nowalk
CDC Brendan Flannery
Alicia Fry
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US Flu VE Network Methods
Enrollees: Outpatients aged 6 months with acute respiratory illness with cough 7 days duration Design: Test-negative case-control design Odds of PCR-confirmed influenza among vaccinated compared to unvaccinated
enrollees Vaccinated: at least one dose of 2016?17 flu vaccine according to medical
records, immunization registries, and/or self-report with date and location Analysis: VE = (1 ? adjusted OR) x 100% Adjusted for site, age, sex, race/ethnicity, self-rated general health status, days
from onset to enrollment, and calendar time of onset
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