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Comparing Cell Structures and Organelles

Supplemental Materials

1. Assessing Prior Knowledge: Students entering 9th grade Biology are expected to have a foundational knowledge for the structure and function of cell structures and organelles. The following activities are designed to help teachers assess how students have retained this foundational content learned in 7th grade life science. Students should be encouraged to refer to these materials throughout the remaining investigations for comparing cell structures and organelles.

a. Cell Structures and Functions Magna Cell Worksheet

b. Cell Structures and Functions Matching

c. Cell Structures and Functions Bingo (Use statements from Cell Structures and Functions Matching Sheet to call out definitions for Bingo terms)

2. Cell Case Studies: Cell Case Studies have been included in this kit to help make student learning relevant. Seven case studies are included as the elaborate portion of this ASIM Lab. Students will become doctors for a day. They will be given a case history and will use this information to make a diagnosis based on the understanding of how cell structures and organelles interact. The case study activity was designed by Rebeca Balkcom of Auburn Junior High School and presented at ASTA 2016. Session Title: “STEMing the Standards Through Case Studies.”

Comparing Cell Structures and Organelles Magna Cell Worksheet Name: ______________________

Date: ______________________

| | |

| |Cell Type: _____________________________________ |

| |Justification: _____________________________________ |

| | |

| |[pic] |

| | |

| |Cell Type: _____________________________________ |

|[pic] |Justification: _____________________________________ |

| |[pic] |

Comparing Cell Structures and Organelles Magna Cell Worksheet KEY

Record the number of each organelle in its correct location(s)

|Label cell types, differentiate prokaryotic cells from eukaryotic cells and provide| |

|justification. The following cell structures and organelles can be found in one or|Cell Type: Bacteria Cell, (Prokaryote) |

|more of the cell types on this sheet. Match the letter of each organelle or |Justification: No nucleus |

|structure to its correct location(s). | |

| |[pic] |

| | |

| |Cell Type: Animal Cell, Eukaryote |

| |Justification: Contains a nucleus and membrane bound organelles |

|[pic] |[pic] |

Comparing Cell Structures and Organelles Review Name: ______________________

For each statement, choose the best match from the list below: Date: ______________________

A. centrioles

B. lysosomes

C. cell membrane

D. mitochondria

E. cell wall

F. nucleoid

G. nucleus

H. plasmid

I. chloroplasts

J. ribosomes

K. chromatin

L. rough ER

M. smooth ER

N. cilia and flagella

O. pilli

P. nucleolus

Q. vacuoles

R. golgi bodies

S. plastids

T. capsule

U. cytoplasm

V. prokaryotes

W. eukaryotes

X. microtubules

Y. microfilaments

1. Powerhouse of the cell; site of ATP production (glucose converted to ATP) _____

2. Supports the shape of an entire cell _____

3. Semi-permeable phospholipid bilayer; membrane found in bacteria, Protista, fungi, plant, and

animal cells _____

4. Bags of enzymes used to digest particles and bacteria; they work in conjunction with vacuoles _____

5. Control center of eukaryotic cells, contains nucleolus and DNA _____

6. Membranous structure that synthesizes lipids(fats) _____

7. Storage sacs; plant cells have a single large one; animal cells have many small ones _____

8. Sites for photosynthesis; found only in plant cells; contain chlorophyll _____

9. Locomotive structures found in prokaryotes and eukaryotes; made of microtubules _____

10. Made mostly of cellulose in plant cells; encases or surrounds plant cells to provide a characteristic

shape; also found in bacteria and fungi cells but composed of different substances _____

11. Watery substance that fills the interior of cells and suspends structures and or organelles;

contains factors for signaling cell processes _____

12. Membranous structure that synthesizes and transports proteins; studded with ribosomes _____

13. Uncoiled DNA; coils into chromosomes during cell division _____

14. Only found in animal cells; form spindle fibers during cell division _____

15. Location in eukaryotic cells where ribosomes are formed _____

16. Cells that contain a nucleus and membrane bound organelles _____

17. Site of protein synthesis; found on rough ER and in cytoplasm _____

18. Single cells that do not contain a nucleus _____

19. Processes, packages, and stores the lipids(fats) and proteins produced by the ER _____

20. Small circular DNA molecule that is separated from the nucleoid in bacteria cells _____

21. Nucleus-like region in prokaryotes; containS most genetic information; not bound by a membrane _____

22. Structure in prokaryotes that lies outside of the cell wall; provides protection and support _____

23. Hair like structures on the surface of prokaryotes(bacteria); transfer DNA during conjugation _____

24. Structures found only in plant cells; chloroplasts are one type _____

25. Involved in muscle contraction in larger organisms

Comparing Cell Structures and Organelles Review - KEY

1. D

2. X

3. C

4. B

5. G

6. M

7. Q

8. I

9. N

10. E

11. U

12. L

13. K

14. A

15. P

16. W

17. J

18. V

19. R

20. H

21. F

22. T

23. O

24. S

25. Y

CELL BINGO CARD AND WORD LIST

| | | | | |

| | | | | |

| | | | | |

| | |Free | | |

| | |Space | | |

| | | | | |

| | | | | |

Cell Bingo Instructions:

Using a pen, write in 24 of the words from the list below in random order. The Teacher will read meanings for each term. Place a bingo chip on the terms that match descriptions read by teacher. Bingo occurs with 5 down, 5 across, or 5 on a diagonal. Full card bingo can also be played.

centrioles

lysosomes

cell membrane

mitochondria

cell wall

nucleoid

nucleus

plasmid

chloroplasts

ribosomes

chromatin

rough ER

smooth ER

cilia and flagella

pilli

nucleolus

vacuoles

golgi bodies

plastids

capsule

cytoplasm

prokaryotes

eukaryotes

microtubules

microfilaments

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #1

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• Seven year-old male

• Experiencing fatigue for the past 2 weeks

• Muscle weakness at recess and P.E.

• Low endurance

• Loss of coordination

• Progressive difficult walking

Physical Examination:

• Difficulty breathing

o Patient is only receiving 60% of air needed

• Awkward gait (the way the patient walked into the room)

• Muscle loss by 10% - most noticeable in quads & biceps

o Deformity of muscles

Laboratory Results

• Cells have abnormal shape

• Cell division is abnormal

• Impaired intracellular movement of materials

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle?

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #2

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 16-month-old male

• Slower to start crawling

• Cannot walk on his own yet

• Continuously falling down when he does walk

Physical Examination:

• Enlarged calves

• Muscle loss by 10% - most noticeable in quads & biceps

o Deformity of muscles

• Waddling gait

Laboratory Results

• High levels of an enzyme released into blood when muscles are being destroyed

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #3

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 2-day-old male

• Low birth-weight

o 4 pds. & 5 oz.

• Difficulty suckling/swallowing

• Seizures

• Gastrointestinal bleeding

Physical Examination:

• Enlarged liver

• Low muscle tone/inability to move

• Glaucoma

• Facial deformities

• Impaired hearing

• Jaundiced skin

o Yellowing of the skin

Laboratory Results

• High levels of hydrogen peroxide in cells

• High levels of fats and amino acids in cells

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #4

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 55 year-old female

• Excellent health to date

• Psychological stress

• Recently won lottery

• Marital stress

• Recent onset of:

o Fatigue

o Headaches

o Excessive salivation

o Nausea

o Vomiting

o Diarrhea

o Vertigo

o Abdominal pain

o Weight loss

Physical Examination:

• Swelling of eyelids

• Partial limb paralysis

• Hyperkeratosis (increased pigmentation) of skin on palms & soles

• White banding on fingernails

• Muscle weakness

Laboratory Results

• Low levels of ATP production

• Unusually high levels of arsenic

• Abnormal levels of cell death

o Not due to apoptosis (programmed cell death)

▪ Rather cell death appears to be due to lack of energy to maintain homeostasis due to low ATP levels

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic,

bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you precribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #5

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 42 year-old male

• No major health issue to date

• Notable increase in weight over past month – gain of 17 pounds

• Recent lethargy

• Patient is on a new eating regimen

•

Physical Examination:

• Enlarged liver

• Muscle weakness

Laboratory Results

• Negative for hepatitis

• Excessive glycogen granules in liver

• High levels of fat in liver – abnormal fat metabolism

• Low testosterone levels

• Abnormal cell calcium balance

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #6

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 40-year-old female

• Experienced tremors all her life in her left hand

o Sometimes carried up her arm

• Recently she has noticed that the tremors have spread to the other side of her body

o Tongue, chin, and lips have been shaking

Physical Examination:

o Tremor in both hands when held out in front of her

o Stiffness in both legs and forearms

o Slow gait coming into the office

o Slurring of words

Laboratory Results

• Increase in hydrogen peroxide in blood

• Abnormal high amount of thyroid levels

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Cell Case Studies

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #7

Hello interns! Presented to you here is a “case study”; in this folder is a compilation of documents concerning a patient experiencing some symptoms. It is your job to use what you know and give the best diagnosis of the patient! These folders contain confidential information concerning the patient’s medical histories, so for their privacy – names were removed.

Patient’s History:

• 22-year-old male

• Normal health

• College student

o Lack of sleep

o In dorm – lives with many other students

• Began to feel fatigue 2 days ago

Physical Examination:

• High fever of 102.3

• Cough

• Sore throat

• Running nose

• Body aches

• Headache

• Chills

Laboratory Results

• Blood work

o High number of white blood cells

• Swab of throat

o Negative for Strep Throat

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease?

2. What is the malfunctioning organelle? (There may be more than 1!!)

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Studies Key

Rebeca Balkcom, Auburn Jr. High, ASTA 2016, Grades 9-12,“STEMing the Standards through Case Studies”

Case Study #1 - Key

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Genetic Disease Sickle Cell

2. What is the malfunctioning organelle? Ribosomes, mitochondria, cytoskeleton

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 2

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Muscular dystrophy

2. What is the malfunctioning organelle? (There may be more than 1!!) Ribosomes, Rough ER

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 3

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Fetal Alcohol syndrome

2. What is the malfunctioning organelle? (There may be more than 1!!) peroxisomes, ribosomes, smooth ER

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 4

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Arsenic poisoning

2. What is the malfunctioning organelle? (There may be more than 1!!) mitochondria, ribosomes

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 5

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Eating too much fast food

2. What is the malfunctioning organelle? (There may be more than 1!!) smooth ER, rough ER, mitochondria

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 6

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Parkinson's Disease

2. What is the malfunctioning organelle? (There may be more than 1!!) Cell membrane, peroxisomes

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

Case Study # 7

Diagnosis: (on a separate sheet of paper, answer the following questions)

1. Given his symptoms and current condition, what do you think is affecting his body? Is it a genetic, bacterial, or viral disease? Flu

2. What is the malfunctioning organelle? (There may be more than 1!!) mitochondria, cell membrane (homeostasis),

3. How would you help cure this patient? Would you prescribe medication or physical therapy?

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Label cell types, differentiate prokaryotic cells from eukaryotic cells and provide justification. The following cell structures and organelles can be found in one or more of the cell types on this sheet. Match the letter of each organelle or structure to its correct location(s).

A. centrioles M. smooth ER

B. lysosome N. flagella

C. cell membrane O. pilli

D. mitochondria P. nucleolus

E. cell wall Q. vacuole

F. nucleoid R. golgi bodies

G. nucleus S. capsule

H. plasmid T. cytoplasm

I. chloroplast U. microtubule(s)

J. ribosome V. large central vacuole

K. chromatin W. microfilament

L. rough ER

Cell Type: ___________________________________

Justification: ___________________________________

A. centrioles

B. lysosome

C. cell membrane

D. mitochondria

E. cell wall

F. nucleoid

G. nucleus

H. plasmid

I. chloroplast

J. ribosome(s)

K. chromatin

L. rough ER

M. smooth ER

N. flagella

O. pilli

P. nucleolus

Q. vacuole

R. golgi bodies

S. capsule

T. cytoplasm

U. microtubule(s)

V. large central vacuole

W. microfilament(s)

Cell Type: Plant Cell, Eukaryote

Justification: Contains chloroplasts, a nucleus, and membrane bound organelles

membrane bound organelles

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