PBHS

José M. Bermúdez et al, developed extended release tablets of 500 mg of Ciprofloxacin based on swellable drug polyelectrolyte matrices (SDPM). A set of complexes of carbomer, ciprofloxacin and sodium, (CB–Cip) 50Nax, having a molar ratio Cip/CB acid group of 0.5 and variable proportions of Na+ was used to prepare SDPM. ................
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