Lippincott Williams & Wilkins
Supplemental ContentAppendix Figure 1 : Sample Creation DiagramAppendix Table 1. ICD-9 Codes Used to Identify TKA ReadmissionsCMS-defined Diagnosis*ICD-9-CM CodeAcute myocardial infarction410.x0, 410.x1 Pneumonia480.x, 481, 482.0-482.2, 482.3x, 482.4x, 482.8x, 482.9, 483.0, 483.1, 483.8, 485, 486, 487.0, 488.11, 507.0, 997.32Sepsis/septicemia/shock038.0x, 038.1x-038.4x, 038.8, 038.9, 785.52, 785.59, 790.7, 995.91, 995.92, 998.0xSurgical site bleeding719.10, 719.16, 719.17, 998.11, 998.12, 998.13 AND 1 of the following procedure codes: 39.98, 86.04Pulmonary embolism415.11, 415.13, 415.19DeathMechanical complications996.40, 996.41, 996.42, 996.44, 996.47, 996.49Periprosthetic joint infection/wound infection996.66, 996.67, 998.3x, 998.5x, 998.6, 998.83 AND 1 of the following procedure codes: 00.70-00.73, 00.80-00.84, 78.65-78.67, 80.05, 80.06, 80.09, 81.53, 81.55, 81.59, 86.04, 86.22, 86.28*Eight diagnoses designated by the CMS as TKA-specific complications ()Appendix Table 2. List of drugs and drug classesBenzodiazepenesAlprazolam, chlordiazepoxide, clonazepam, clorazepate, diazepam, estazolam, flurazepam, halazepam, lorazepam, midazolam, oxazepam, prazepam, quazepam, temazepam, triazolamAntidepressants SSRICitalopram, escitalopram, paroxetine, fluoxetine, fluvoxamine, sertraline SNRIDesvenlafaxine, duloxetine, levomilnacipran, milnacipran, tofenacin, venlafaxine SMSVilazodone, vortioxetine SARIEtoperidone, trazodone, nefazodone NRIReboxetine, viloxazine TCAsAmitriptyline, butriptyline, clomipramine, desipramine, dosulepin, imipramine, iprindole, lofepramine, melitracen, nortriptyline, protriptyline, trimipramine, opipramol, tianeptine TeCAsAmoxapine, maprotiline, mianserin, mirtazapine, setiptiline MAOIsIsocarboxazid, phenelzine, tranylcypromine, selegiline, metralindole, moclobemide, pirlindole, toloxatoneAntipsychotics typicalChlorpromazine, thioridazine, mesoridazine, levomepromazine, loxapine, molindone, perphenazine, thiothixene, trifluoperazine, haloperidol, fluphenazine, droperidol, zuclopenthixol, prochlorperazine atypicalAmisulpride, aripiprazole, asenapine, blonanserine, clotiapine, clozapine, iloperidone, lurasidone,mosapramine, olanzapine, paliperidone, perospirone, quetiapine, remoxipride, risperidone, sertindole,sulpiride, ziprasidone, zotepineKey: SSRI=selective serotonin reuptake inhibitor; SNRI=serotonin/norepinephrine reuptake inhibitor; SMS=serotonin modulator/stimulator; SARI=serotonin antagonist/reuptake inhibitor; NRI=norepinephrine reuptake inhibitor; TCA=tricyclic antidepressant; TeCA=tetracyclic antidepressant; MAOI=monamine oxidase inhibitor ................
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