Science Manuscript Template



BMEFResearch Article TemplateUse this template to speed the processing of your paper.We need to accurately record the title, authors, abstract, and other component parts of your paper so we can enrich it with reference links and an accurate layout.Please use the actual template starting on page 3, which includes more specific formatting instructions.When you are ready to submit, please delete this box with all its contents and the next page.Your manuscript should start on Page 1, Line 1.Submit your paper at HYPERLINK "" NOTES AND INSTRUCTIONSUse the line numbering formatting tool to ease in the review processUse paragraph spacing of 1.5 or 2 (double)Manuscripts should be no more than 5000 words (Introduction through Discussion, excluding the abstract, materials and methods, and references)Figures and Tables: Maximum of 6 figures and 3 tables (9 data elements total)Initial submission: Provide the figures and tables two ways:(1) Each figure and table should be submitted as a separate file. Acceptable file types are listed on Information for Authors <LINK: ;. These files will be used if the manuscript is accepted without revision. (2) Figures and tables should also be embedded within the Word file close to where they are mentioned in the text. This facilitates evaluation by the editors and reviewers. Figures should be called out within the text and numbered in the order that they are mentioned. Within the text, figure legends (also known as captions) should be listed immediately after each figure as it appears embedded in the text. All figure titles should be phrases or sentences; do not mix the two styles. Each legend should be a maximum of ~200 words. Nomenclature, abbreviations, symbols, and units used in a figure legend (and in the figure itself) should be consistent throughout the data elements (figures, tables, and supplementary materials). Any that are not used in the text should be defined in the legend. Individual figure panels are in boldface when first mentioned in a legend.Figure 1. Short title of the first figure. The title is an overall description of the figure, in boldface. It is followed by additional text. Each legend should be placed immediately after its corresponding figure. Indicate figure parts with bold capital letters at first mention: (A), (B), etc. Tables should supplement, not duplicate, the text or figures. They should be called out within the text and numbered in the order that they are called out. Within the text, the table title and legend should precede the body of the table where it appears embedded in the text. Format tables using the Word Table commands and structures. Do not use spaces or tabs to create tables. Every vertical column should have a heading, followed by a unit of measure (if any) in parentheses. Units should not change within a column. Centered headings of the body of the table can be used to break the entries into groups.Footnotes should appear beneath the last row of the table and should contain information relevant to specific cells of the table; use the following symbols in order, as needed: *, ?, ?, §, ||, ?, #, **, ??, etc. Do not use footnotes in column or row headings; include any such details in sentence form in the table legend.Table 1. Short title of the first table. Start table legends with a title (short description of the table). Describe information required to understand the column headings. Footnotes should only be used for information relevant to specific cells, not information relevant to an entire row or column.References: Maximum of 40 references.Number cited references consecutively in the order of their first mention, for example [1,2]. The numbered reference list may be provided in any format that includes complete author list, article title, journal title, volume and page (or DOI) and date of publication. DOI should be provided whenever possible. Front MatterTitle Provide a title for your paper. The title can be a maximum of 100 characters, including spaces. AuthorsAuthors should be listed in order of contribution to the paper, by first name, then middle initial (if any), followed by last name and separated by commas. The author list should be one single paragraph with no line breaks. Authors should be listed in the order in which they will appear in the published version if the manuscript is accepted. Author names should be complete and include initials or suffixes, because names as they appear on the manuscript file will be used for indexing if the manuscript is published.Affiliations Use superscript numbers (1, 2, 3) to designate author affiliations. Each affiliation should be preceded by superscript numbers corresponding to the author list, and each affiliation should end with a period.Each affiliation should be a separate paragraph.You can include group authors, but please include a list of the actual authors (the group members) in the Supplementary Materials.If all authors have the same affiliation, no superscript numbers are required.Use an asterisk (*) to identify the corresponding author, and be sure to include that person’s e-mail address. Use symbols (in this order: ?, ?, §, ||, ?, #, ??, ??, etc.) for author notes, such as present addresses, “These authors contributed equally to this work” notations, and similar information.Example all authors with same affiliation: Jianchao Sun, Yong Lu, Hao Yang, Mo Han, Lianyi Shao, and Jun Chen*Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), College of Chemistry, Nankai University, Tianjin, 300071 China.*Corresponding author. Email: chenabc@nankai.Example authors with multiple affiliations and author footnotes:Hao-xiang Li1?, María A. Rosendo-López2?, Yi-fan Zhu1, Xu-dong Fan1, Daniel J. Torrent, Sr.3, Bin Liang1*, Jian-chun Cheng1, and Johan Christensen2,3*1Key Laboratory of Modern Acoustics, MOE, Institute of Acoustics, Department of Physics, Collaborative Innovation Center of Advanced Microstructures, Nanjing University, Nanjing 210093, China2Department of Physics, Universidad Carlos III de Madrid, 28916 Leganés, Madrid, Spain3GROC, UJI, Institut de Noves Tecnologies de la Imatge (INIT), Universitat Jaume I, 12080 Castellè, SpainCorresponding authors: Bin Liang;liangbin@nju. and Johan Christensen; johan.christensen@uc3m.es??These authors contributed equally to this work.AbstractUse a Structured Abstract with the sections indicated below. Do not include citations or undefined abbreviations in the abstract. Any abbreviations that appear in the title should be defined in the abstract. The length should not exceed 250 words. The sections to include are: Objective: An opening sentence that states the objective of the researchImpact Statement: Brief description about the novelty and impact of the researchIntroduction: Enough background information to give context to the studyMethods: A brief statement of the primary methods used by the studyResults: A brief statement of primary resultsConclusion: A short concluding sentence of the main take-home point(s) of the studyKeywordsProvide 6-10 keywords for your manuscript. List these in alphabetical order in a separate paragraph after the abstract. Use words or phrases that people might use in searches. The main ones should also appear in the abstract; however, some keywords may be distinct from those already in the title and abstract. Consistent repetition of important terms and phrases in your title, abstract, and subheadings will aid search engine optimization, which means that other researchers will be able to find and cite your work.MAIN TEXTIntroductionThe manuscript should start with a brief introduction that lays out the problem addressed by the research and describes the paper’s importance. The scientific question being investigated should be described in detail. The Introduction should provide sufficient background information to make the article understandable to readers in other disciplines and provide enough context to ensure that the implications of the experimental findings are clear. Results The Results should describe the experiments performed and the findings observed. The Results section should be divided into subsections to delineate different experimental themes. Subheadings should either be all phrases or all complete sentences. All data must be shown either in the main text or in the Supplementary Materials. All data, both that in the main part of the manuscript and that in the Supplementary Materials, should be presented in the Results. No data should be presented for the first time in the Discussion. Data (such as from Western blots) should be appropriately quantified from multiple independent experiments. Inclusion of biological data from individual experiments that have not been repeated at least twice is generally not permitted.Subheadings must be either all complete sentences or all phrases. They should be brief, ideally less than 10 words. Subheadings should not end in a period. The Results section may have as many level 1 subheadings as are necessary.Figures and tables must be called out in numerical order. For example, the first mention of any panel of Figure 3 cannot precede the first mention of all panels of Figure 2. The supplementary figures (for example, Figure S1) and tables (Table S1) must also be called out in numerical order. All figures and tables should have a title and a legend.Display equations should be set on their own line. Number display equations a at the right — (1), (2), etc. Use MathType (recommended) or the legacy equation editor in Word (Insert menu; select insert object; select word equation). Equations entered in simple LaTeX should be checked to ensure that they will convert accurately (Word 2007 and higher can convert simple LaTeX equations). Do not use the native Word 2007, 2008, 2010, or 2011 equation editor. This can produce errors when converted to MathML, the online markup language used by the journal.Mathematical expressions within a sentence of text should be created with ordinary Word characters; if this is not possible, then use MathType (or the equivalent). Only use MathType when necessary — for example, characters with overbars or carets, with stacked superscripts and subscripts, or within square root symbols.Discussion Include a Discussion that summarizes (but does not merely repeat) the conclusions, compares or integrates the findings with previously published results, and elaborates on the implications or significance of the work. If applicable, there should be a paragraph outlining the limitations of the results and interpretation, as well as a discussion of the steps that need to be taken for the findings to be applied. Please avoid claims of priority. Materials and MethodsThe Materials and Methods section should provide sufficient information to allow replication of the results. Under exceptional circumstances, when a particularly lengthy description is required, a portion of the materials and methods can be included in the Supplementary Materials. Experimental and Technical DesignBegin the Materials and Methods with a subsection titled “Experimental and Technical Design” describing the objectives and design of the study. If applicable, include a diagram or flowchart of the entire experimental design to illustrate the most important elements, such as specific materials, treatments, measurements, data collection, and methods of data analysis. This will facilitate the ability of editors, reviewers, and readers to understand and follow the concept of the study, the study design, and the results.Subsection 1…nThe rest of the Material and Methods should be divided by short subheadings for each method or technique. When a particularly lengthy description is required, a portion of the materials and methods can be included in the Supplementary Materials. This option should be used only in exceptional circumstances.Animal and Human StudiesStudies involving animals or humans should include separate sections with the subheadings “Animals and Study Approval” or “Subjects and Study Approval,” as appropriate for animal or human research, respectively. All human studies must have been approved by the appropriate institutional review board(s). The Subjects and Study Approval subsection must include a specific declaration of such approval, including a statement indicating that written informed consent was received from participants prior to inclusion in the study.?For animal models, the Animals and Study Approval subsection must include the precise genotype, strain, source, number of backcrosses, sex, and age of animals. Additionally, all animal studies must have been approved by the appropriate institutional review board(s). This subsection must include a specific declaration of such approval.Statistical AnalysisThe final subsection of the Materials and Methods should be titled “Statistical Analysis.” This subsection describes the statistical methods with enough detail for verification of the results by a knowledgeable reader with access to the original data. Although this subsection describes the statistical methods used, the values for N, P, and the specific statistical test performed for each experiment should be included in the appropriate figure or table legend or main text. AcknowledgmentsAcknowledgments, when needed, should include the following information in the order listed below, starting with the word “Acknowledgments” in bold. Please use the subhead and boldface layout as shown below:General: Thank others for any contributions. Any person providing reagents or mentioned in the Materials and Methods should also be listed here.Author contributions: Describe the contributions of each author (use initials) to the paper. Funding: Include all funding sources, including grant numbers and funding agencies. Indicate with initials the authors who received the funding. Competing interests: Include any financial interests of the authors that could be perceived as being a conflict of interest. Also include any awarded or filed patents pertaining to the results presented in the paper. If there are no competing interests, please state so.Data availability: Submission of a manuscript to BMEF implies that the data are freely available upon request or have been deposited into an open database, like NCBI. If data can be obtained from an archive, include the accession number, if available, or a placeholder text for the accession number when it becomes available. Also, provide information about any materials that require a Material Transfer Agreement (MTA), specifying which materials and where to obtain the MTA. SUPPLEMENTARY MATERIALSInclude supporting text, figures, and tables at the end of the main manuscript file if possible. Alternatively, Supplementary Materials can be included as a separate Word file. Include titles and captions for additional file types that cannot be embedded into the Word file. Supplementary figures should be embedded in the Word file in the order in which they are mentioned in the text, with the legends directly below the figure. All should include a title in addition to a legend.Any references cited in the Supplementary Materials must already appear in the reference list; no separate supplementary reference list should be created.Supplementary Materials may include additional author notes — for example, a list of group authors.Supplementary Materials should be listed in the following order: supplementary text or materials and methods, supplementary figures, supplementary tables, other supplementary files (such as movies, data, interactive images, computer code, or database files), and references only cited in the supplementary materials. Be sure to submit all Supplementary Materials with the manuscript. Supplementary Materials should be named as follows: Supplementary textFigures S1 to S#Tables S1 to S#Movies S1 to S#Data files S1 to S#Computer code S1 to S#Audio files S1 to S#REFERENCESThere is only one reference list for all sources cited in the main text, figure and table legends, and Supplementary Materials. Do not include a second reference list in the Supplementary Materials section. References cited only in the Supplementary Materials section are not counted toward the limit of 40 references.In the text, references should be numbered consecutively in the order of their first citation. Citations of references in the text should be identified using numbers in square brackets e.g., “as discussed by Liu [9]”; “as discussed elsewhere [9, 10]”. All references should be cited within the text and uncited references will be removed.Authors may submit the reference section in any numbered style for journal articles, as long as the style includes all authors (initials and last name), article title, journal title (or abbreviation), volume, year of publication, and pages. For journals that do not use page numbers, include the article number. For journals that do not use volume numbers, include the date of publication and DOI. If available, include a DOI for each reference.List all authors by first initial(s) and last name. Do not use op. cit., ibid., 3-m dashes, en dashes, or et al. (in place of the complete list of authors’ names).For online resources that do not have a DOI, include full URL, title of the page, source of the information, and date of access.If accepted, BMEF will reformat the references in Chicago style. Authors are responsible for ensuring that the information in each reference is complete and accurate.Explanatory notes should be called out and cited separately and not be included as part of another cited reference. Manuscripts should not include footnotes; information should be integrated into the text. ................
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