Bronchoconstriction due to Cold Weather in COPD: The Roles of Direct ...

Bronchoconstriction dueto Cold Weatherin COPD* TheRoles of Direct AirwayEffects andCutaneous Reflex Mechanisms Heikki O. Koskela, MD;AnnaKKoskela, MD;and Hannu O. Tukiainen, MD Toclarify howcold weathermayinduce bronchoconstriction in patients with COPD,a series of challenges wereperformedin 20patients with COPDin stable condition as well as in 13healthy subjects. Awhole-bodyexposureto-17 ... ................
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