Engineered nanomaterials: A review of the toxicology and ...

Intratracheal instillation of particulates at loading of more than about 100 – 200 µg per rat lung has the potential to cause effects associated with particulate overload of the lung. Exposing mice by nasopharyngeal aspiration provides better particle dispersion in the lower lung and is not as susceptible to lung overload issues as is ... ................
................