EMBRYOLOGY

Heart development. Starts as horseshoe tube cranial to the cranial neural folds, brought to thoracic cavity by cranial folding. BMPs (TGF-( family) plus WNT inhibition induces NKX 2-5, which establishes cardiogenic field. TBX5 (T Box transcription factor) regulates septation. Endocardium = lines heart cavity = same as blood vessels. ................
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