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The in-vitro dissolution study was performed on the brands, according to FDA,USP dissolution profile in three different PH (1.2),(4.5), and (6.8) at37ºC ,using the USP apparatus II, then f1 ,f2 were determined for the time intervals of 10, 15, 30, 45 and 60 minutes, and dissolution efficiencies were calculated. ................
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