Society of Toxicology



675005-7791451617348-598167NorCal SOT Fall Symposium 2019The Hematopoietic System: Therapeutics, Toxic Responses, and Strategies for 21st CenturyOctober 24th, 2019South San Francisco Conference Center, 255 South Airport Boulevard, South San Francisco, CA 94080 Morning Session7:30 am – 8:30 amRegistration & Breakfast8:30 am – 8:45 amOpening Message from The NorCal PresidentDinah Misner, PhD, DABT, DSP, Aligos Therapeutics8:45 am – 9:30 amPlenary Speaker: Toxicology or Exaggerated PharmacologyBrian Cathers, PhD, Global Blood Therapeutics9:30 am – 10:15 amFDA Guidance on Nonclinical Development of Pharmaceuticals for Severely Debilitating or LifeThreatening Hematologic DisordersJohn Leighton, PhD, Office of Hematology and Oncology Products, US Food and Drug Administration (remote)10:15 am – 10:45 amCoffee Break10:45 am – 11:30 amDe-Risking Hematopoietic Toxicity – The Need for More Complex In Vitro ToolsAaron Fullerton, PhD, Genentech11:30 pm – 1:00 pmLunch Break: Lunch with ExpertsAfternoon Session1:00 pm – 1:15 pmChapter Announcements and Acknowledgements1:15 am – 2:00 pmThe Hematologic Toxicity of Anilide Herbicides and Its Use in Characterizing the Human Health Risk of PropanilPeter Lohstroh, PhD, Department of Pesticide Regulation, California Environmental Protection Agency2:00 pm – 2:45 pmCholinesterase Inhibition by Pesticides and Determinants of Intra- and Inter-Individual VariabilityHeather Bolstad, PhD, Office of Environmental Health Hazard Assessment, California Environmental Protection Agency 2:45 pm – 3:00 pmCoffee Break3:00 pm – 3:45 pmMechanisms and Investigations into HematotoxicityNancy Everds, DVM, DACVP, Seattle Genetics3:45 pm – 4:30 pmSB-525, a Novel Gene Therapy for Treatment of Hemophilia AKathleen Meyer, MPH, PhD, DABT, Sangamo Therapeutics4:30 pm – 6:00 pmReception & Networking ................
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