Ars.els-cdn.com
Supplementary materialSupplementary Figures ………………………………….. page 2-3Supplementary Tables ………………………………….. page 4-7Supplementary figuresFigure S1. Pointwise data along the corticospinal tract and the superior longitudinal fasciculusThe figure shows the raw FA scores mapped along CST and SLF(p) (left panel) and p-values resulting from significance tests of group differences in FA along CST and SLF(p). The long segment showing a significant group difference in SLF(p) is clearly in the crossing fiber region (corona radiata) where the SLF meets the CST. It is also clear on the left hand side of the figure that FA drops for both group in the CST in the region where the two pathways meet. Supplementary tablesTable S1. Mediator analysis: To what extent are cortical thickness group differences mediated by reduced FA?Cortical endpoint regionDirect effect of VLBW (NDE)Indirect effect of VLBW (NIE)Total effect of VLBWEstimate95% CIEstimate95%CIForceps major, left.063(.009, .114)-.001(-.015, .004).062Forceps major, right.081(.030, .131)-.002(-.017, .002).079Forceps minor, left.122(.056, .192).018*(.002, .050).140Forceps minor, right.081(-.024, .143).023*(.002, .058).104left UNC, frontal .026(-.049, .102).015(-.056, .101).041right UNC, frontal.089(.019, .159).026(-.004 , .071).115left UNC, temporal -.001(-.215, .199)-.031(-.232, .161)-.032right UNC, temporal.135(-.015, .278)-.040(-.148, .044).095left SLF(p), posterior-.072(-.121, -.022).00(-.026, .013)-.072right SLF(p), posterior-.068(-.125, -.016)-.007(-.035, .021)-.075left SLF(p), anterior.020 (-.032, .080).010(-.002, .034).030right SLF(p), anterior-.004(-.050, 057).005(-.011, .024).001left SLF(t), posterior-.024(-.082, .031).002(-.012, .025)-.022right SLF(t), posterior-.055(-.113, .008)-.017(-.057, .010)-.072left SLF(t), anterior.010(-.046, .069).002(-.008, .026).012right SLF(t), anterior. 315(-.015, .278)-.040(-.148,.044).355This table shows the natural direct (NDE) and indirect (NIE) effects on cortical thickness, of being born preterm with VLBW. The total effect of VLBW on cortical thickness is the sum of NDE and NIE. A positive total effect means that VLBW has thicker cortex than the control group. The NIE is the effect of VLBW on cortical thickness that is mediated by FA; * indicates statistically significant estimate of NIE. Bold NIE confidence intervals indicate significant mediation at the 0.05 level. Abbreviations: FA: fractional anisotropy; SLF(p/t): superior longitudinal fasciculus (parietal/temporal part), UNC: uncinate fasciculus; VLBW: Very Low Birth Weight. ................
................
In order to avoid copyright disputes, this page is only a partial summary.
To fulfill the demand for quickly locating and searching documents.
It is intelligent file search solution for home and business.