Karyotyping Activity
VIRTUAL LAB: University of Arizona Karyotyping Activity
In this activity, you will use a computer model to look at chromosomes and prepare a karyotype. You will diagnose patients for abnormalities and learn the correct notation for characterizing karyotypes.
How to turn in your completed assignment:
1. You can type your work on this existing word document.
2. Save your word document on your desktop with your name (first and last) and period. For example John Doe- Period 5
3. Then you can send it to me either through your email as an attachment or by sharing it on Google doc.
My email address is dplama@cps.edu
SITE 1 Go to: biology.arizona.edu - click on Karyotyping under human biology
OR
Click on Patient Histories. You will be completing a karyotype for Patient A, B & C
Patient A (Click on the link to "Complete Patient A's Karyotype")
*Match the chromosome to its homolog. After all the matches are complete you'll analyze your patient. (Scroll down to view your completed karyotype).
1. What is patient A's history (summarize)
2. How many total chromosomes are in your karyotype - count them _________
(The last set of chromosomes is the sex chromosomes, if you have two large chromosomes, your patient is XX (female), one large and one small indicates and XY (male).
3. What sex chromosomes does your patient have ________
4. Which chromosome set has an extra + _______
5. What diagnosis would you give this patient (what disease)? ______________
Patient B - click on the link to go to Patient B and repeat the above process.
6. What is Patient B's history (summarize)
7. How many total chromosomes are in your karyotype - count them _________
8. What sex chromosomes does your patient have ________
9. Which chromosome set has an extra + _______
10. Finish the notation for this patient's karyotype : 47 X _____
11. What is the diagnosis? __________________________________
Patient C - click on the link to go to Patient C and repeat the above process.
12. What is patient C's history (summarize)? _________________________________
13. How many total chromosomes are in your karyotype - count them _________
14. What sex chromosomes does your patient have ________
15. Which chromosome set has an extra + _______
16. Write out the correct notation for this karyotype. ________
17. What is the diagnosis? _________________________________________
SITE 2:
Go to Making a Karyotype - Try it yourself
Create your own karyotype - turning on hints is okay.
18. What did you find difficult about matching the chromosomes? ____________________
19. Show your teacher and get initials when complete on the computer or with hard copy._________
SITE 3: Go to -Using Karyotypes to Predict Genetic Disorders
20. What is trisomy? ______________________________________
21. What is monosomy? ____________________________________
22. What is a terminal deletion? ______________________________
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