Possible Side Effects of Erlotinib, Gemcitabine



Possible Side Effects of Erlotinib, Gemcitabine (Table Version Date: October 8, 2013)

|COMMON, SOME MAY BE SERIOUS |

|In 100 people receiving Erlotinib, Gemcitabine, more than 20 and up to 100 may have: |

|Rash |

|Diarrhea, vomiting, nausea, weight loss, loss of appetite |

|Tiredness |

|Cough, shortness of breath |

|Fever |

|Sores in mouth which may cause difficulty swallowing |

|Swelling of the body |

|Flu-like symptoms of muscle pain, fever, headache, chills and fatigue |

|Hair loss |

|Infection, especially when white blood cell count is low |

|Bruising, bleeding |

|Anemia which may require a blood transfusion |

|Muscle weakness |

|Muscle ache |

|Blood in urine |

|Feeling of "pins and needles" in arms and legs |

|Numbness and tingling of the arms and legs |

|Difficulty sleeping |

|Hearing loss |

|OCCASIONAL, SOME MAY BE SERIOUS |

|In 100 people receiving Erlotinib, Gemcitabine, from 4 to 20 may have: |

|Heart attack |

|Severe skin rash with blisters and peeling which can involve inside of mouth and other parts of the body |

|Itching |

|Passing gas, heartburn |

|Internal bleeding which may cause black tarry stool, blood in vomit |

|Liver damage which may cause yellowing of eyes and skin |

|Swelling, redness, dryness or sores of the eye |

|Worry, depression |

|Constipation |

|Fluid in the organs which may cause low blood pressure, shortness of breath, swelling of ankles |

|Brain damage, Reversible Posterior Leukoencephalopathy Syndrome, which may cause headache, seizure, blindness |

|RARE, AND SERIOUS |

|In 100 people receiving Erlotinib, Gemcitabine, 3 or fewer may have: |

|A tear or hole in the stomach that may require surgery |

|Kidney and liver damage which may require dialysis |

|A tear or hole in the eye which may cause blindness |

|Scarring of the lungs |

|Fluid around lungs |

|Blockage of the airway |

|Damage to organs which may cause shortness of breath |

|Stroke which may cause paralysis, weakness |

|Blood clot which may cause swelling, pain, shortness of breath |

|Abnormal heartbeat |

|Heart failure which may cause shortness of breath, swelling of ankles, and tiredness |

|Blisters on the skin |

|Sores on the skin |

|Allergic reaction which may cause rash, low blood pressure, wheezing, shortness of breath, swelling of the face or throat |

|Kidney damage which may require dialysis |

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