Npac-aiipc.org



Urgent need to increase the rates of diagnosing, treating and controlling hypertension in older women. A call for all levels of government, health professional associations, health charities and clinicians to reengage and to take action.Supported by the Nurse Practitioner Association of Canada, Nurse Practitioner Association of Alberta, Canadian Nurses Association, Canadian Pharmacists Association, College of Family Physicians of Canada, Hypertension Canada, and the Heart and Stroke Foundation of Canada.Increased blood pressure is a leading reversible risk for death and disability in Canada and around the world ADDIN EN.CITE <EndNote><Cite><Author>Institute for Health Metrics and Evaluation</Author><Year>2020</Year><RecNum>6540</RecNum><DisplayText>(1)</DisplayText><record><rec-number>6540</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1504299360" guid="828450a5-0bd6-4bb1-b5d0-a0978ad08add">6540</key></foreign-keys><ref-type name="Web Page">12</ref-type><contributors><authors><author>Institute for Health Metrics and Evaluation,</author></authors></contributors><titles><title>Global Burden of Disease Study</title><short-title>Global Burden of Disease </short-title></titles><volume>2020</volume><number>March 25</number><reprint-edition>NOT IN FILE</reprint-edition><keywords><keyword>Disease</keyword><keyword>evaluation</keyword><keyword>Health</keyword></keywords><dates><year>2020</year></dates><label>6543</label><urls><related-urls><url> 10</custom2><access-date>2013/09/10/</access-date></record></Cite></EndNote>(1). About one half of cardiovascular disease is caused by increased blood pressure ADDIN EN.CITE <EndNote><Cite><Author>Campbell</Author><Year>2019</Year><RecNum>7626</RecNum><DisplayText>(2)</DisplayText><record><rec-number>7626</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1587566562" guid="a886f2c3-c7ba-4306-82c6-0c93d1861a28">7626</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Campbell, Norm R. C.</author><author>Schutte, Aletta E.</author><author>Varghese, Cherian V.</author><author>Ordunez, Pedro</author><author>Zhang, Xin-Hua</author><author>Khan, Taskeen</author><author>Sharman, James E.</author><author>Whelton, Paul K.</author><author>Parati, Gianfranco</author><author>Weber, Michael A.</author><author>Orías, Marcelo</author><author>Jaffe, Marc G.</author><author>Moran, Andrew E.</author><author>Liane Plavnik, Frida</author><author>Ram, Venkata S.</author><author>Brainin, Michael</author><author>Owolabi, Mayowa O.</author><author>Ramirez, Augstin J.</author><author>Barbosa, Eduardo</author><author>Bortolotto, Luiz Aparecido</author><author>Lackland, Daniel T.</author></authors></contributors><titles><title>S?o Paulo call to action for the prevention and control of high blood pressure: 2020</title><secondary-title>The Journal of Clinical Hypertension</secondary-title></titles><periodical><full-title>The Journal of Clinical Hypertension</full-title></periodical><pages>1744-1752</pages><volume>21</volume><number>12</number><dates><year>2019</year></dates><isbn>1524-6175</isbn><urls><related-urls><url>;(2). Reducing blood pressure with antihypertensive therapy is one of the most effective clinical interventions to prevent death and disability ADDIN EN.CITE <EndNote><Cite><Author>Campbell</Author><Year>2019</Year><RecNum>7626</RecNum><DisplayText>(2)</DisplayText><record><rec-number>7626</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1587566562" guid="a886f2c3-c7ba-4306-82c6-0c93d1861a28">7626</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Campbell, Norm R. C.</author><author>Schutte, Aletta E.</author><author>Varghese, Cherian V.</author><author>Ordunez, Pedro</author><author>Zhang, Xin-Hua</author><author>Khan, Taskeen</author><author>Sharman, James E.</author><author>Whelton, Paul K.</author><author>Parati, Gianfranco</author><author>Weber, Michael A.</author><author>Orías, Marcelo</author><author>Jaffe, Marc G.</author><author>Moran, Andrew E.</author><author>Liane Plavnik, Frida</author><author>Ram, Venkata S.</author><author>Brainin, Michael</author><author>Owolabi, Mayowa O.</author><author>Ramirez, Augstin J.</author><author>Barbosa, Eduardo</author><author>Bortolotto, Luiz Aparecido</author><author>Lackland, Daniel T.</author></authors></contributors><titles><title>S?o Paulo call to action for the prevention and control of high blood pressure: 2020</title><secondary-title>The Journal of Clinical Hypertension</secondary-title></titles><periodical><full-title>The Journal of Clinical Hypertension</full-title></periodical><pages>1744-1752</pages><volume>21</volume><number>12</number><dates><year>2019</year></dates><isbn>1524-6175</isbn><urls><related-urls><url>;(2). The risk from hypertension increases with other risk factors, the most prominent one being age, so particular care must be taken to control hypertension in the elderly.Between 2000 and 2010, Canada gained a reputation of having the highest national rate of controlling hypertension, with reductions in cardiovascular death strongly associated with the increased treatment of hypertensionPEVuZE5vdGU+PENpdGU+PEF1dGhvcj5DYW1wYmVsbDwvQXV0aG9yPjxZZWFyPjIwMDk8L1llYXI+

PFJlY051bT4yNTg0PC9SZWNOdW0+PERpc3BsYXlUZXh0PigzKTwvRGlzcGxheVRleHQ+PHJlY29y

ZD48cmVjLW51bWJlcj4yNTg0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVO

IiBkYi1pZD0idDBmemFwNXQwcDJ3cmNldjJlbDVmdHo1dnRwd3ZzZnM1MDB6IiB0aW1lc3RhbXA9

IjE1MDQyOTM5MTUiIGd1aWQ9ImVlMTU4Y2Y3LTk5NTItNGM1Mi1hMTM1LThmM2IyZTUxYjE0ZiI+

MjU4NDwva2V5PjxrZXkgYXBwPSJFTldlYiIgZGItaWQ9IiI+MDwva2V5PjwvZm9yZWlnbi1rZXlz

PjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29udHJpYnV0

b3JzPjxhdXRob3JzPjxhdXRob3I+Q2FtcGJlbGwsIE4uIFIuPC9hdXRob3I+PGF1dGhvcj5CcmFu

dCwgUi48L2F1dGhvcj48YXV0aG9yPkpvaGFuc2VuLCBILjwvYXV0aG9yPjxhdXRob3I+V2Fsa2Vy

LCBSLiBMLjwvYXV0aG9yPjxhdXRob3I+V2llbGdvc3osIEEuPC9hdXRob3I+PGF1dGhvcj5Pbnlz

a28sIEouPC9hdXRob3I+PGF1dGhvcj5HYW8sIFIuIE4uPC9hdXRob3I+PGF1dGhvcj5TYW1iZWxs

LCBDLjwvYXV0aG9yPjxhdXRob3I+UGhpbGxpcHMsIFMuPC9hdXRob3I+PGF1dGhvcj5NY0FsaXN0

ZXIsIEYuIEEuPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxl

PkluY3JlYXNlcyBpbiBhbnRpaHlwZXJ0ZW5zaXZlIHByZXNjcmlwdGlvbnMgYW5kIHJlZHVjdGlv

bnMgaW4gY2FyZGlvdmFzY3VsYXIgZXZlbnRzIGluIENhbmFkYTwvdGl0bGU+PHNlY29uZGFyeS10

aXRsZT5IeXBlcnRlbnNpb248L3NlY29uZGFyeS10aXRsZT48c2hvcnQtdGl0bGU+SW5jcmVhc2Vz

IGluIGFudGloeXBlcnRlbnNpdmUgcHJlc2NyaXB0aW9ucyBhbmQgcmVkdWN0aW9ucyBpbiBjYXJk

aW92YXNjdWxhciBldmVudHMgaW4gQ2FuYWRhPC9zaG9ydC10aXRsZT48L3RpdGxlcz48cGVyaW9k

aWNhbD48ZnVsbC10aXRsZT5IeXBlcnRlbnNpb248L2Z1bGwtdGl0bGU+PC9wZXJpb2RpY2FsPjxw

YWdlcz4xMjgtMTM0PC9wYWdlcz48dm9sdW1lPjUzPC92b2x1bWU+PG51bWJlcj4yPC9udW1iZXI+

PHJlcHJpbnQtZWRpdGlvbj5OT1QgSU4gRklMRTwvcmVwcmludC1lZGl0aW9uPjxrZXl3b3Jkcz48

a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29yZD5BZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPkFn

ZWQsODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QW5hbHlzaXM8L2tleXdvcmQ+PGtleXdv

cmQ+QW50aWh5cGVydGVuc2l2ZSBBZ2VudHM8L2tleXdvcmQ+PGtleXdvcmQ+YW50aWh5cGVydGVu

c2l2ZSB0aGVyYXB5PC9rZXl3b3JkPjxrZXl3b3JkPmFudGloeXBlcnRlbnNpdmU8L2tleXdvcmQ+

PGtleXdvcmQ+Q2FuYWRhPC9rZXl3b3JkPjxrZXl3b3JkPmNhcmRpb3Zhc2N1bGFyIGRpc2Vhc2U8

L2tleXdvcmQ+PGtleXdvcmQ+Q2FyZGlvdmFzY3VsYXIgRGlzZWFzZXM8L2tleXdvcmQ+PGtleXdv

cmQ+Y2FyZGlvdmFzY3VsYXIgZXZlbnRzPC9rZXl3b3JkPjxrZXl3b3JkPmNhcmRpb3Zhc2N1bGFy

PC9rZXl3b3JkPjxrZXl3b3JkPkNvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ZGVhdGg8

L2tleXdvcmQ+PGtleXdvcmQ+ZGlhZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPkRydWcgVGhlcmFw

eTwva2V5d29yZD48a2V5d29yZD5kcnVnPC9rZXl3b3JkPjxrZXl3b3JkPkRydWdzPC9rZXl3b3Jk

PjxrZXl3b3JkPmVkdWNhdGlvbjwva2V5d29yZD48a2V5d29yZD5lcGlkZW1pb2xvZ3k8L2tleXdv

cmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPmhlYWx0aCBjYXJlPC9rZXl3b3Jk

PjxrZXl3b3JkPkhlYWx0aCBTdXJ2ZXlzPC9rZXl3b3JkPjxrZXl3b3JkPkhlYWx0aDwva2V5d29y

ZD48a2V5d29yZD5oZWFydCBmYWlsdXJlPC9rZXl3b3JkPjxrZXl3b3JkPmhlYXJ0PC9rZXl3b3Jk

PjxrZXl3b3JkPkhvc3BpdGFsaXphdGlvbjwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8L2tleXdv

cmQ+PGtleXdvcmQ+aHlwZXJ0ZW5zaW9uPC9rZXl3b3JkPjxrZXl3b3JkPkluY2lkZW5jZTwva2V5

d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPm1hbmFnZW1lbnQgb2YgaHlwZXJ0

ZW5zaW9uPC9rZXl3b3JkPjxrZXl3b3JkPm1hbmFnZW1lbnQ8L2tleXdvcmQ+PGtleXdvcmQ+TWlk

ZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+TW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPk15

b2NhcmRpYWwgSW5mYXJjdGlvbjwva2V5d29yZD48a2V5d29yZD5uYXRpb25hbCBoZWFsdGggcHJv

Z3JhbXM8L2tleXdvcmQ+PGtleXdvcmQ+UGh5c2ljaWFuJmFwb3M7cyBQcmFjdGljZSBQYXR0ZXJu

czwva2V5d29yZD48a2V5d29yZD5wcmVzY3JpcHRpb24gZHJ1Z3M8L2tleXdvcmQ+PGtleXdvcmQ+

cHJlc2NyaXB0aW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZlbnRpb24gJmFtcDsgQ29udHJvbDwv

a2V5d29yZD48a2V5d29yZD5wdWJsaWMgaGVhbHRoPC9rZXl3b3JkPjxrZXl3b3JkPlJpc2sgRmFj

dG9yczwva2V5d29yZD48a2V5d29yZD5TdGF0aXN0aWNzICZhbXA7IE51bWVyaWNhbCBEYXRhPC9r

ZXl3b3JkPjxrZXl3b3JkPnN0cm9rZTwva2V5d29yZD48a2V5d29yZD5UaGVyYXBldXRpYyBVc2U8

L2tleXdvcmQ+PGtleXdvcmQ+VGhlcmFweTwva2V5d29yZD48a2V5d29yZD50cmVhdG1lbnQ8L2tl

eXdvcmQ+PGtleXdvcmQ+dHJlbmRzPC9rZXl3b3JkPjxrZXl3b3JkPldvcmxkIEhlYWx0aCBPcmdh

bml6YXRpb248L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAwOTwveWVhcj48L2Rh

dGVzPjx1cmxzPjwvdXJscz48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB=

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5DYW1wYmVsbDwvQXV0aG9yPjxZZWFyPjIwMDk8L1llYXI+

PFJlY051bT4yNTg0PC9SZWNOdW0+PERpc3BsYXlUZXh0PigzKTwvRGlzcGxheVRleHQ+PHJlY29y

ZD48cmVjLW51bWJlcj4yNTg0PC9yZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVO

IiBkYi1pZD0idDBmemFwNXQwcDJ3cmNldjJlbDVmdHo1dnRwd3ZzZnM1MDB6IiB0aW1lc3RhbXA9

IjE1MDQyOTM5MTUiIGd1aWQ9ImVlMTU4Y2Y3LTk5NTItNGM1Mi1hMTM1LThmM2IyZTUxYjE0ZiI+

MjU4NDwva2V5PjxrZXkgYXBwPSJFTldlYiIgZGItaWQ9IiI+MDwva2V5PjwvZm9yZWlnbi1rZXlz

PjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29udHJpYnV0

b3JzPjxhdXRob3JzPjxhdXRob3I+Q2FtcGJlbGwsIE4uIFIuPC9hdXRob3I+PGF1dGhvcj5CcmFu

dCwgUi48L2F1dGhvcj48YXV0aG9yPkpvaGFuc2VuLCBILjwvYXV0aG9yPjxhdXRob3I+V2Fsa2Vy

LCBSLiBMLjwvYXV0aG9yPjxhdXRob3I+V2llbGdvc3osIEEuPC9hdXRob3I+PGF1dGhvcj5Pbnlz

a28sIEouPC9hdXRob3I+PGF1dGhvcj5HYW8sIFIuIE4uPC9hdXRob3I+PGF1dGhvcj5TYW1iZWxs

LCBDLjwvYXV0aG9yPjxhdXRob3I+UGhpbGxpcHMsIFMuPC9hdXRob3I+PGF1dGhvcj5NY0FsaXN0

ZXIsIEYuIEEuPC9hdXRob3I+PC9hdXRob3JzPjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxl

PkluY3JlYXNlcyBpbiBhbnRpaHlwZXJ0ZW5zaXZlIHByZXNjcmlwdGlvbnMgYW5kIHJlZHVjdGlv

bnMgaW4gY2FyZGlvdmFzY3VsYXIgZXZlbnRzIGluIENhbmFkYTwvdGl0bGU+PHNlY29uZGFyeS10

aXRsZT5IeXBlcnRlbnNpb248L3NlY29uZGFyeS10aXRsZT48c2hvcnQtdGl0bGU+SW5jcmVhc2Vz

IGluIGFudGloeXBlcnRlbnNpdmUgcHJlc2NyaXB0aW9ucyBhbmQgcmVkdWN0aW9ucyBpbiBjYXJk

aW92YXNjdWxhciBldmVudHMgaW4gQ2FuYWRhPC9zaG9ydC10aXRsZT48L3RpdGxlcz48cGVyaW9k

aWNhbD48ZnVsbC10aXRsZT5IeXBlcnRlbnNpb248L2Z1bGwtdGl0bGU+PC9wZXJpb2RpY2FsPjxw

YWdlcz4xMjgtMTM0PC9wYWdlcz48dm9sdW1lPjUzPC92b2x1bWU+PG51bWJlcj4yPC9udW1iZXI+

PHJlcHJpbnQtZWRpdGlvbj5OT1QgSU4gRklMRTwvcmVwcmludC1lZGl0aW9uPjxrZXl3b3Jkcz48

a2V5d29yZD5BZHVsdDwva2V5d29yZD48a2V5d29yZD5BZ2VkPC9rZXl3b3JkPjxrZXl3b3JkPkFn

ZWQsODAgYW5kIG92ZXI8L2tleXdvcmQ+PGtleXdvcmQ+QW5hbHlzaXM8L2tleXdvcmQ+PGtleXdv

cmQ+QW50aWh5cGVydGVuc2l2ZSBBZ2VudHM8L2tleXdvcmQ+PGtleXdvcmQ+YW50aWh5cGVydGVu

c2l2ZSB0aGVyYXB5PC9rZXl3b3JkPjxrZXl3b3JkPmFudGloeXBlcnRlbnNpdmU8L2tleXdvcmQ+

PGtleXdvcmQ+Q2FuYWRhPC9rZXl3b3JkPjxrZXl3b3JkPmNhcmRpb3Zhc2N1bGFyIGRpc2Vhc2U8

L2tleXdvcmQ+PGtleXdvcmQ+Q2FyZGlvdmFzY3VsYXIgRGlzZWFzZXM8L2tleXdvcmQ+PGtleXdv

cmQ+Y2FyZGlvdmFzY3VsYXIgZXZlbnRzPC9rZXl3b3JkPjxrZXl3b3JkPmNhcmRpb3Zhc2N1bGFy

PC9rZXl3b3JkPjxrZXl3b3JkPkNvbXBsaWNhdGlvbnM8L2tleXdvcmQ+PGtleXdvcmQ+ZGVhdGg8

L2tleXdvcmQ+PGtleXdvcmQ+ZGlhZ25vc2lzPC9rZXl3b3JkPjxrZXl3b3JkPkRydWcgVGhlcmFw

eTwva2V5d29yZD48a2V5d29yZD5kcnVnPC9rZXl3b3JkPjxrZXl3b3JkPkRydWdzPC9rZXl3b3Jk

PjxrZXl3b3JkPmVkdWNhdGlvbjwva2V5d29yZD48a2V5d29yZD5lcGlkZW1pb2xvZ3k8L2tleXdv

cmQ+PGtleXdvcmQ+RmVtYWxlPC9rZXl3b3JkPjxrZXl3b3JkPmhlYWx0aCBjYXJlPC9rZXl3b3Jk

PjxrZXl3b3JkPkhlYWx0aCBTdXJ2ZXlzPC9rZXl3b3JkPjxrZXl3b3JkPkhlYWx0aDwva2V5d29y

ZD48a2V5d29yZD5oZWFydCBmYWlsdXJlPC9rZXl3b3JkPjxrZXl3b3JkPmhlYXJ0PC9rZXl3b3Jk

PjxrZXl3b3JkPkhvc3BpdGFsaXphdGlvbjwva2V5d29yZD48a2V5d29yZD5IdW1hbnM8L2tleXdv

cmQ+PGtleXdvcmQ+aHlwZXJ0ZW5zaW9uPC9rZXl3b3JkPjxrZXl3b3JkPkluY2lkZW5jZTwva2V5

d29yZD48a2V5d29yZD5NYWxlPC9rZXl3b3JkPjxrZXl3b3JkPm1hbmFnZW1lbnQgb2YgaHlwZXJ0

ZW5zaW9uPC9rZXl3b3JkPjxrZXl3b3JkPm1hbmFnZW1lbnQ8L2tleXdvcmQ+PGtleXdvcmQ+TWlk

ZGxlIEFnZWQ8L2tleXdvcmQ+PGtleXdvcmQ+TW9ydGFsaXR5PC9rZXl3b3JkPjxrZXl3b3JkPk15

b2NhcmRpYWwgSW5mYXJjdGlvbjwva2V5d29yZD48a2V5d29yZD5uYXRpb25hbCBoZWFsdGggcHJv

Z3JhbXM8L2tleXdvcmQ+PGtleXdvcmQ+UGh5c2ljaWFuJmFwb3M7cyBQcmFjdGljZSBQYXR0ZXJu

czwva2V5d29yZD48a2V5d29yZD5wcmVzY3JpcHRpb24gZHJ1Z3M8L2tleXdvcmQ+PGtleXdvcmQ+

cHJlc2NyaXB0aW9uPC9rZXl3b3JkPjxrZXl3b3JkPlByZXZlbnRpb24gJmFtcDsgQ29udHJvbDwv

a2V5d29yZD48a2V5d29yZD5wdWJsaWMgaGVhbHRoPC9rZXl3b3JkPjxrZXl3b3JkPlJpc2sgRmFj

dG9yczwva2V5d29yZD48a2V5d29yZD5TdGF0aXN0aWNzICZhbXA7IE51bWVyaWNhbCBEYXRhPC9r

ZXl3b3JkPjxrZXl3b3JkPnN0cm9rZTwva2V5d29yZD48a2V5d29yZD5UaGVyYXBldXRpYyBVc2U8

L2tleXdvcmQ+PGtleXdvcmQ+VGhlcmFweTwva2V5d29yZD48a2V5d29yZD50cmVhdG1lbnQ8L2tl

eXdvcmQ+PGtleXdvcmQ+dHJlbmRzPC9rZXl3b3JkPjxrZXl3b3JkPldvcmxkIEhlYWx0aCBPcmdh

bml6YXRpb248L2tleXdvcmQ+PC9rZXl3b3Jkcz48ZGF0ZXM+PHllYXI+MjAwOTwveWVhcj48L2Rh

dGVzPjx1cmxzPjwvdXJscz48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPgB=

ADDIN EN.CITE.DATA (3). In the last decade, the rates of diagnosing, treating and controlling hypertension in older women (age > 60 years) have been decreasing, while hypertension control in men remained high and stable (Figure 1) ADDIN EN.CITE <EndNote><Cite><Author>Leung</Author><RecNum>7624</RecNum><DisplayText>(4)</DisplayText><record><rec-number>7624</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1586890772" guid="186b4b5d-4e42-48e4-bdd0-714631eda64d">7624</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Leung, Alexander A.</author><author>Williams, Jeanne V. A.</author><author>McAlister, Finlay A.</author><author>Campbell, Norman R. C.</author><author>Padwal, Raj S.</author><author>Tran, Karen</author><author>Tsuyuki, Ross</author><author>McAlister, Finlay A.</author><author>Campbell, Norman R. C.</author><author>Khan, Nadia</author><author>Padwal, Raj</author><author>Quan, Hude</author><author>Leung, Alexander A.</author></authors></contributors><titles><title>Worsening Hypertension Awareness, Treatment, and Control Rates in Canadian Women Between 2007 and 2017</title><secondary-title>Canadian Journal of Cardiology</secondary-title></titles><periodical><full-title>Canadian Journal of Cardiology</full-title></periodical><dates></dates><publisher>Elsevier</publisher><isbn>0828-282X</isbn><urls><related-urls><url>;(4). Several countries now have higher rates of hypertension control in women than Canada PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFJlY051bT43NTYzPC9SZWNOdW0+

PERpc3BsYXlUZXh0Pig1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVjLW51bWJlcj43NTYzPC9y

ZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1pZD0idDBmemFwNXQwcDJ3

cmNldjJlbDVmdHo1dnRwd3ZzZnM1MDB6IiB0aW1lc3RhbXA9IjE1NjQyNzgxMzAiIGd1aWQ9IjZm

OTViN2FmLTQ5OTEtNDRiNS1hMzUzLTQzMTc3NzIzMjZlYSI+NzU2Mzwva2V5PjwvZm9yZWlnbi1r

ZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29udHJp

YnV0b3JzPjxhdXRob3JzPjxhdXRob3I+WmhvdSwgQmluPC9hdXRob3I+PGF1dGhvcj5EYW5hZWks

IEdvb2Rhcno8L2F1dGhvcj48YXV0aG9yPlN0ZXZlbnMsIEdyZXRjaGVuIEEuPC9hdXRob3I+PGF1

dGhvcj5CaXhieSwgSG9ub3I8L2F1dGhvcj48YXV0aG9yPlRhZGRlaSwgQ3Jpc3RpbmE8L2F1dGhv

cj48YXV0aG9yPkNhcnJpbGxvLUxhcmNvLCBSb2RyaWdvIE0uPC9hdXRob3I+PGF1dGhvcj5Tb2xv

bW9uLCBCZXRobGVoZW08L2F1dGhvcj48YXV0aG9yPlJpbGV5LCBMZWFubmUgTS48L2F1dGhvcj48

YXV0aG9yPkRpIENlc2FyZSwgTWFyaWFjaGlhcmE8L2F1dGhvcj48YXV0aG9yPkl1cmlsbGksIE1h

cmlhIExhdXJhIENhbWluaWE8L2F1dGhvcj48YXV0aG9yPlJvZHJpZ3Vlei1NYXJ0aW5leiwgQW5k

cmVhPC9hdXRob3I+PGF1dGhvcj5aaHUsIEF1YnJpYW5uYTwvYXV0aG9yPjxhdXRob3I+SGFqaWZh

dGhhbGlhbiwgS2F2ZWg8L2F1dGhvcj48YXV0aG9yPkFtdXp1LCBBbnRvaW5ldHRlPC9hdXRob3I+

PGF1dGhvcj5CYW5lZ2FzLCBKb3PDqSBSLjwvYXV0aG9yPjxhdXRob3I+QmVubmV0dCwgSmFtZXMg

RS48L2F1dGhvcj48YXV0aG9yPkNhbWVyb24sIENocmlzdGluZTwvYXV0aG9yPjxhdXRob3I+Q2hv

LCBZdW1pPC9hdXRob3I+PGF1dGhvcj5DbGFya2UsIEphbmluZTwvYXV0aG9yPjxhdXRob3I+Q3Jh

aWcsIENvcmEgTC48L2F1dGhvcj48YXV0aG9yPkNydXosIEp1YW4gSi48L2F1dGhvcj48YXV0aG9y

PkdhdGVzLCBMb3Vpc2U8L2F1dGhvcj48YXV0aG9yPkdpYW1wYW9saSwgU2ltb25hPC9hdXRob3I+

PGF1dGhvcj5HcmVnZywgRWR3YXJkIFcuPC9hdXRob3I+PGF1dGhvcj5IYXJkeSwgUmViZWNjYTwv

YXV0aG9yPjxhdXRob3I+SGF5ZXMsIEFsaXNvbiBKLjwvYXV0aG9yPjxhdXRob3I+SWtlZGEsIE5h

eXU8L2F1dGhvcj48YXV0aG9yPkphY2tzb24sIFJvZCBULjwvYXV0aG9yPjxhdXRob3I+SmVubmlu

Z3MsIEdhcnJ5PC9hdXRob3I+PGF1dGhvcj5Kb2ZmcmVzLCBNaWNoZWw8L2F1dGhvcj48YXV0aG9y

PktoYW5nLCBZb3VuZy1IbzwvYXV0aG9yPjxhdXRob3I+S29za2luZW4sIFNlcHBvPC9hdXRob3I+

PGF1dGhvcj5LdWgsIERpYW5hPC9hdXRob3I+PGF1dGhvcj5LdWphbGEsIFVyaG8gTS48L2F1dGhv

cj48YXV0aG9yPkxhYXRpa2FpbmVuLCBUaWluYTwvYXV0aG9yPjxhdXRob3I+TGVodGltw6RraSwg

VGVyaG88L2F1dGhvcj48YXV0aG9yPkxvcGV6LUdhcmNpYSwgRXN0aGVyPC9hdXRob3I+PGF1dGhv

cj5MdW5kcXZpc3QsIEFubmFtYXJpPC9hdXRob3I+PGF1dGhvcj5NYWdnaSwgU3RlZmFuaWE8L2F1

dGhvcj48YXV0aG9yPk1hZ2xpYW5vLCBEaWFubmEgSi48L2F1dGhvcj48YXV0aG9yPk1hbm4sIEpp

bSBJLjwvYXV0aG9yPjxhdXRob3I+TWNMZWFuLCBSYWNoYWVsIE0uPC9hdXRob3I+PGF1dGhvcj5N

Y0xlYW4sIFNjb3R0IEIuPC9hdXRob3I+PGF1dGhvcj5NaWxsZXIsIEpvZHkgQy48L2F1dGhvcj48

YXV0aG9yPk1vcmdhbiwgS2FyZW48L2F1dGhvcj48YXV0aG9yPk5ldWhhdXNlciwgSGFubmVsb3Jl

IEsuPC9hdXRob3I+PGF1dGhvcj5OaWlyYW5lbiwgVGVlbXUgSi48L2F1dGhvcj48YXV0aG9yPk5v

YWxlLCBNYXJpYW5uYTwvYXV0aG9yPjxhdXRob3I+T2gsIEt5dW5nd29uPC9hdXRob3I+PGF1dGhv

cj5QYWxtaWVyaSwgTHVpZ2k8L2F1dGhvcj48YXV0aG9yPlBhbnphLCBGcmFuY2VzY288L2F1dGhv

cj48YXV0aG9yPlBhcm5lbGwsIFdpbnNvbWUgUi48L2F1dGhvcj48YXV0aG9yPlBlbHRvbmVuLCBN

YXJra3U8L2F1dGhvcj48YXV0aG9yPlJhaXRha2FyaSwgT2xsaTwvYXV0aG9yPjxhdXRob3I+Um9k

csOtZ3Vlei1BcnRhbGVqbywgRmVybmFuZG88L2F1dGhvcj48YXV0aG9yPlJveSwgSm9lbCBHLiBS

LjwvYXV0aG9yPjxhdXRob3I+U2Fsb21hYSwgVmVpa2tvPC9hdXRob3I+PGF1dGhvcj5TYXJnYW5h

cywgR2lzZWxsZTwvYXV0aG9yPjxhdXRob3I+U2VydmFpcywgSmVubmlmZXI8L2F1dGhvcj48YXV0

aG9yPlNoYXcsIEpvbmF0aGFuIEUuPC9hdXRob3I+PGF1dGhvcj5TaGlidXlhLCBLZW5qaTwvYXV0

aG9yPjxhdXRob3I+U29sZnJpenppLCBWaW5jZW56bzwvYXV0aG9yPjxhdXRob3I+U3RhdnJlc2tp

LCBCaWxsPC9hdXRob3I+PGF1dGhvcj5UYW4sIEVuZyBKb288L2F1dGhvcj48YXV0aG9yPlR1cmxl

eSwgTWFyaWEgTC48L2F1dGhvcj48YXV0aG9yPlZhbnV6em8sIERpZWdvPC9hdXRob3I+PGF1dGhv

cj5WaWlrYXJpLUp1bnR1cmEsIEVpcmE8L2F1dGhvcj48YXV0aG9yPldlZXJhc2VrZXJhLCBEZWVw

YTwvYXV0aG9yPjxhdXRob3I+RXp6YXRpLCBNYWppZDwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRy

aWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5Mb25nLXRlcm0gYW5kIHJlY2VudCB0cmVuZHMgaW4gaHlw

ZXJ0ZW5zaW9uIGF3YXJlbmVzcywgdHJlYXRtZW50LCBhbmQgY29udHJvbCBpbiAxMiBoaWdoLWlu

Y29tZSBjb3VudHJpZXM6IGFuIGFuYWx5c2lzIG9mIDEyMyBuYXRpb25hbGx5IHJlcHJlc2VudGF0

aXZlIHN1cnZleXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+VGhlIExhbmNldDwvc2Vjb25kYXJ5

LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlRoZSBMYW5jZXQ8L2Z1bGwt

dGl0bGU+PC9wZXJpb2RpY2FsPjxkYXRlcz48L2RhdGVzPjxwdWJsaXNoZXI+RWxzZXZpZXI8L3B1

Ymxpc2hlcj48aXNibj4wMTQwLTY3MzY8L2lzYm4+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0

dHBzOi8vZG9pLm9yZy8xMC4xMDE2L1MwMTQwLTY3MzYoMTkpMzExNDUtNjwvdXJsPjwvcmVsYXRl

ZC11cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9TMDE0MC02NzM2

KDE5KTMxMTQ1LTY8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDE5LzA3

LzI3PC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn==

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5aaG91PC9BdXRob3I+PFJlY051bT43NTYzPC9SZWNOdW0+

PERpc3BsYXlUZXh0Pig1KTwvRGlzcGxheVRleHQ+PHJlY29yZD48cmVjLW51bWJlcj43NTYzPC9y

ZWMtbnVtYmVyPjxmb3JlaWduLWtleXM+PGtleSBhcHA9IkVOIiBkYi1pZD0idDBmemFwNXQwcDJ3

cmNldjJlbDVmdHo1dnRwd3ZzZnM1MDB6IiB0aW1lc3RhbXA9IjE1NjQyNzgxMzAiIGd1aWQ9IjZm

OTViN2FmLTQ5OTEtNDRiNS1hMzUzLTQzMTc3NzIzMjZlYSI+NzU2Mzwva2V5PjwvZm9yZWlnbi1r

ZXlzPjxyZWYtdHlwZSBuYW1lPSJKb3VybmFsIEFydGljbGUiPjE3PC9yZWYtdHlwZT48Y29udHJp

YnV0b3JzPjxhdXRob3JzPjxhdXRob3I+WmhvdSwgQmluPC9hdXRob3I+PGF1dGhvcj5EYW5hZWks

IEdvb2Rhcno8L2F1dGhvcj48YXV0aG9yPlN0ZXZlbnMsIEdyZXRjaGVuIEEuPC9hdXRob3I+PGF1

dGhvcj5CaXhieSwgSG9ub3I8L2F1dGhvcj48YXV0aG9yPlRhZGRlaSwgQ3Jpc3RpbmE8L2F1dGhv

cj48YXV0aG9yPkNhcnJpbGxvLUxhcmNvLCBSb2RyaWdvIE0uPC9hdXRob3I+PGF1dGhvcj5Tb2xv

bW9uLCBCZXRobGVoZW08L2F1dGhvcj48YXV0aG9yPlJpbGV5LCBMZWFubmUgTS48L2F1dGhvcj48

YXV0aG9yPkRpIENlc2FyZSwgTWFyaWFjaGlhcmE8L2F1dGhvcj48YXV0aG9yPkl1cmlsbGksIE1h

cmlhIExhdXJhIENhbWluaWE8L2F1dGhvcj48YXV0aG9yPlJvZHJpZ3Vlei1NYXJ0aW5leiwgQW5k

cmVhPC9hdXRob3I+PGF1dGhvcj5aaHUsIEF1YnJpYW5uYTwvYXV0aG9yPjxhdXRob3I+SGFqaWZh

dGhhbGlhbiwgS2F2ZWg8L2F1dGhvcj48YXV0aG9yPkFtdXp1LCBBbnRvaW5ldHRlPC9hdXRob3I+

PGF1dGhvcj5CYW5lZ2FzLCBKb3PDqSBSLjwvYXV0aG9yPjxhdXRob3I+QmVubmV0dCwgSmFtZXMg

RS48L2F1dGhvcj48YXV0aG9yPkNhbWVyb24sIENocmlzdGluZTwvYXV0aG9yPjxhdXRob3I+Q2hv

LCBZdW1pPC9hdXRob3I+PGF1dGhvcj5DbGFya2UsIEphbmluZTwvYXV0aG9yPjxhdXRob3I+Q3Jh

aWcsIENvcmEgTC48L2F1dGhvcj48YXV0aG9yPkNydXosIEp1YW4gSi48L2F1dGhvcj48YXV0aG9y

PkdhdGVzLCBMb3Vpc2U8L2F1dGhvcj48YXV0aG9yPkdpYW1wYW9saSwgU2ltb25hPC9hdXRob3I+

PGF1dGhvcj5HcmVnZywgRWR3YXJkIFcuPC9hdXRob3I+PGF1dGhvcj5IYXJkeSwgUmViZWNjYTwv

YXV0aG9yPjxhdXRob3I+SGF5ZXMsIEFsaXNvbiBKLjwvYXV0aG9yPjxhdXRob3I+SWtlZGEsIE5h

eXU8L2F1dGhvcj48YXV0aG9yPkphY2tzb24sIFJvZCBULjwvYXV0aG9yPjxhdXRob3I+SmVubmlu

Z3MsIEdhcnJ5PC9hdXRob3I+PGF1dGhvcj5Kb2ZmcmVzLCBNaWNoZWw8L2F1dGhvcj48YXV0aG9y

PktoYW5nLCBZb3VuZy1IbzwvYXV0aG9yPjxhdXRob3I+S29za2luZW4sIFNlcHBvPC9hdXRob3I+

PGF1dGhvcj5LdWgsIERpYW5hPC9hdXRob3I+PGF1dGhvcj5LdWphbGEsIFVyaG8gTS48L2F1dGhv

cj48YXV0aG9yPkxhYXRpa2FpbmVuLCBUaWluYTwvYXV0aG9yPjxhdXRob3I+TGVodGltw6RraSwg

VGVyaG88L2F1dGhvcj48YXV0aG9yPkxvcGV6LUdhcmNpYSwgRXN0aGVyPC9hdXRob3I+PGF1dGhv

cj5MdW5kcXZpc3QsIEFubmFtYXJpPC9hdXRob3I+PGF1dGhvcj5NYWdnaSwgU3RlZmFuaWE8L2F1

dGhvcj48YXV0aG9yPk1hZ2xpYW5vLCBEaWFubmEgSi48L2F1dGhvcj48YXV0aG9yPk1hbm4sIEpp

bSBJLjwvYXV0aG9yPjxhdXRob3I+TWNMZWFuLCBSYWNoYWVsIE0uPC9hdXRob3I+PGF1dGhvcj5N

Y0xlYW4sIFNjb3R0IEIuPC9hdXRob3I+PGF1dGhvcj5NaWxsZXIsIEpvZHkgQy48L2F1dGhvcj48

YXV0aG9yPk1vcmdhbiwgS2FyZW48L2F1dGhvcj48YXV0aG9yPk5ldWhhdXNlciwgSGFubmVsb3Jl

IEsuPC9hdXRob3I+PGF1dGhvcj5OaWlyYW5lbiwgVGVlbXUgSi48L2F1dGhvcj48YXV0aG9yPk5v

YWxlLCBNYXJpYW5uYTwvYXV0aG9yPjxhdXRob3I+T2gsIEt5dW5nd29uPC9hdXRob3I+PGF1dGhv

cj5QYWxtaWVyaSwgTHVpZ2k8L2F1dGhvcj48YXV0aG9yPlBhbnphLCBGcmFuY2VzY288L2F1dGhv

cj48YXV0aG9yPlBhcm5lbGwsIFdpbnNvbWUgUi48L2F1dGhvcj48YXV0aG9yPlBlbHRvbmVuLCBN

YXJra3U8L2F1dGhvcj48YXV0aG9yPlJhaXRha2FyaSwgT2xsaTwvYXV0aG9yPjxhdXRob3I+Um9k

csOtZ3Vlei1BcnRhbGVqbywgRmVybmFuZG88L2F1dGhvcj48YXV0aG9yPlJveSwgSm9lbCBHLiBS

LjwvYXV0aG9yPjxhdXRob3I+U2Fsb21hYSwgVmVpa2tvPC9hdXRob3I+PGF1dGhvcj5TYXJnYW5h

cywgR2lzZWxsZTwvYXV0aG9yPjxhdXRob3I+U2VydmFpcywgSmVubmlmZXI8L2F1dGhvcj48YXV0

aG9yPlNoYXcsIEpvbmF0aGFuIEUuPC9hdXRob3I+PGF1dGhvcj5TaGlidXlhLCBLZW5qaTwvYXV0

aG9yPjxhdXRob3I+U29sZnJpenppLCBWaW5jZW56bzwvYXV0aG9yPjxhdXRob3I+U3RhdnJlc2tp

LCBCaWxsPC9hdXRob3I+PGF1dGhvcj5UYW4sIEVuZyBKb288L2F1dGhvcj48YXV0aG9yPlR1cmxl

eSwgTWFyaWEgTC48L2F1dGhvcj48YXV0aG9yPlZhbnV6em8sIERpZWdvPC9hdXRob3I+PGF1dGhv

cj5WaWlrYXJpLUp1bnR1cmEsIEVpcmE8L2F1dGhvcj48YXV0aG9yPldlZXJhc2VrZXJhLCBEZWVw

YTwvYXV0aG9yPjxhdXRob3I+RXp6YXRpLCBNYWppZDwvYXV0aG9yPjwvYXV0aG9ycz48L2NvbnRy

aWJ1dG9ycz48dGl0bGVzPjx0aXRsZT5Mb25nLXRlcm0gYW5kIHJlY2VudCB0cmVuZHMgaW4gaHlw

ZXJ0ZW5zaW9uIGF3YXJlbmVzcywgdHJlYXRtZW50LCBhbmQgY29udHJvbCBpbiAxMiBoaWdoLWlu

Y29tZSBjb3VudHJpZXM6IGFuIGFuYWx5c2lzIG9mIDEyMyBuYXRpb25hbGx5IHJlcHJlc2VudGF0

aXZlIHN1cnZleXM8L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+VGhlIExhbmNldDwvc2Vjb25kYXJ5

LXRpdGxlPjwvdGl0bGVzPjxwZXJpb2RpY2FsPjxmdWxsLXRpdGxlPlRoZSBMYW5jZXQ8L2Z1bGwt

dGl0bGU+PC9wZXJpb2RpY2FsPjxkYXRlcz48L2RhdGVzPjxwdWJsaXNoZXI+RWxzZXZpZXI8L3B1

Ymxpc2hlcj48aXNibj4wMTQwLTY3MzY8L2lzYm4+PHVybHM+PHJlbGF0ZWQtdXJscz48dXJsPmh0

dHBzOi8vZG9pLm9yZy8xMC4xMDE2L1MwMTQwLTY3MzYoMTkpMzExNDUtNjwvdXJsPjwvcmVsYXRl

ZC11cmxzPjwvdXJscz48ZWxlY3Ryb25pYy1yZXNvdXJjZS1udW0+MTAuMTAxNi9TMDE0MC02NzM2

KDE5KTMxMTQ1LTY8L2VsZWN0cm9uaWMtcmVzb3VyY2UtbnVtPjxhY2Nlc3MtZGF0ZT4yMDE5LzA3

LzI3PC9hY2Nlc3MtZGF0ZT48L3JlY29yZD48L0NpdGU+PC9FbmROb3RlPn==

ADDIN EN.CITE.DATA (5). In 90% of Canadian women with uncontrolled blood pressure, the systolic blood pressure is high ADDIN EN.CITE <EndNote><Cite><Author>Wilkins</Author><Year>2012</Year><RecNum>7627</RecNum><DisplayText>(6)</DisplayText><record><rec-number>7627</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1587568474" guid="02fe33c0-2de1-42bb-8087-d63a2e65b862">7627</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Wilkins, K. </author><author>Gee, M. </author><author>Campbell, NRC.</author></authors></contributors><titles><title>The difference in hypertension control between older men and women</title><secondary-title>Health Reports</secondary-title></titles><periodical><full-title>Health Reports</full-title></periodical><pages>3-10</pages><volume>23</volume><dates><year>2012</year></dates><urls></urls></record></Cite></EndNote>(6). Unfortunately, rates of cardiovascular disease in Canada have also started to increase since about 2010, after more than a half century of consistent reductions (figure 2a). Age standardizing the data (figure 2b) show some of the increases in cardiovascular deaths are related to increasing age of the population. The rest of the increase in cardiovascular disease deaths is undoubtedly attributable to the well established, mostly modifiable causes of cardiovascular disease not being effectively prevented and controlled in Canadians (hypertension, dyslipidemia, high glucose, diet, tobacco, lack of physical activity and obesity). Figure 2c shows the trends in disability adjusted life years (DALYS) from cardiovascular disease. The marked increases in DALYS after 2010 are particularly concerning as it reflects largely preventable declines in the quality of life for large numbers of Canadians. Declining rates of hypertension control in older women are likely an explanation for some of the increase in cardiovascular deaths and DALYS but the death rate and DALYS is also increasing in men, highlighting the need to control hypertension and other vascular risk factors (diet, lack of activity, smoking, high blood glucose, high risk alcohol consumption, lipids etc.) in both sexes . Older women are often at moderate to high risk from cardiovascular disease and should at a minimum have blood pressure assessed at all routine clinical visits and those with hypertension (BP> 140/90 mmHg) should be treated and controlled as a core standard of care (table) PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE.DATA (7)*. Many if not most people with hypertension will require two or more drugsPEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE.DATA (7). In those at high cardiovascular risk (e.g., Framingham risk score of > 15%, or aged 75 years or higher), to optimize reduction in death and disability, consider initiating treatment at a systolic blood pressure of > 130 mmHg and lowering the systolic blood pressure to < 120 mm HgPEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE.DATA (7). Persons with diabetes should have a blood pressure treatment threshold of 130/80 mmHg and a target of < 130/80 mm HgPEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE PEVuZE5vdGU+PENpdGU+PEF1dGhvcj5OZXJlbmJlcmc8L0F1dGhvcj48WWVhcj4yMDE4PC9ZZWFy

PjxSZWNOdW0+NzU2NjwvUmVjTnVtPjxEaXNwbGF5VGV4dD4oNyk8L0Rpc3BsYXlUZXh0PjxyZWNv

cmQ+PHJlYy1udW1iZXI+NzU2NjwvcmVjLW51bWJlcj48Zm9yZWlnbi1rZXlzPjxrZXkgYXBwPSJF

TiIgZGItaWQ9InQwZnphcDV0MHAyd3JjZXYyZWw1ZnR6NXZ0cHd2c2ZzNTAweiIgdGltZXN0YW1w

PSIxNTY0MzQwNzA5IiBndWlkPSI3M2ZiNjkxMi02YmE0LTQ1MmYtOWYyOC1iNmRjYmQxYWE2Yjki

Pjc1NjY8L2tleT48L2ZvcmVpZ24ta2V5cz48cmVmLXR5cGUgbmFtZT0iSm91cm5hbCBBcnRpY2xl

Ij4xNzwvcmVmLXR5cGU+PGNvbnRyaWJ1dG9ycz48YXV0aG9ycz48YXV0aG9yPk5lcmVuYmVyZywg

S2FyYSBBLjwvYXV0aG9yPjxhdXRob3I+WmFybmtlLCBLZWxseSBCLjwvYXV0aG9yPjxhdXRob3I+

TGV1bmcsIEFsZXhhbmRlciBBLjwvYXV0aG9yPjxhdXRob3I+RGFzZ3VwdGEsIEthYmVyaTwvYXV0

aG9yPjxhdXRob3I+QnV0YWxpYSwgU29uaWE8L2F1dGhvcj48YXV0aG9yPk1jQnJpZW4sIEtlcnJ5

PC9hdXRob3I+PGF1dGhvcj5IYXJyaXMsIEtldmluIEMuPC9hdXRob3I+PGF1dGhvcj5OYWtobGEs

IE1lcmFuZGE8L2F1dGhvcj48YXV0aG9yPkNsb3V0aWVyLCBMeW5lPC9hdXRob3I+PGF1dGhvcj5H

ZWxmZXIsIE1hcms8L2F1dGhvcj48YXV0aG9yPkxhbWFycmUtQ2xpY2hlLCBNYXhpbWU8L2F1dGhv

cj48YXV0aG9yPk1pbG90LCBBbGFpbjwvYXV0aG9yPjxhdXRob3I+Qm9sbGksIFBldGVyPC9hdXRo

b3I+PGF1dGhvcj5UcmVtYmxheSwgR3V5PC9hdXRob3I+PGF1dGhvcj5NY0xlYW4sIERvbm5hPC9h

dXRob3I+PGF1dGhvcj5QYWR3YWwsIFJhaiBTLjwvYXV0aG9yPjxhdXRob3I+VHJhbiwgS2FyZW4g

Qy48L2F1dGhvcj48YXV0aG9yPkdyb3ZlciwgU3RldmVuPC9hdXRob3I+PGF1dGhvcj5SYWJraW4s

IFNpbW9uIFcuPC9hdXRob3I+PGF1dGhvcj5Nb2UsIEdvcmRvbiBXLjwvYXV0aG9yPjxhdXRob3I+

SG93bGV0dCwgSm9uYXRoYW4gRy48L2F1dGhvcj48YXV0aG9yPkxpbmRzYXksIFBhdHJpY2U8L2F1

dGhvcj48YXV0aG9yPkhpbGwsIE1pY2hhZWwgRC48L2F1dGhvcj48YXV0aG9yPlNoYXJtYSwgTWlr

ZTwvYXV0aG9yPjxhdXRob3I+RmllbGQsIFRoYWxpYTwvYXV0aG9yPjxhdXRob3I+V2VpbiwgVGhl

b2RvcmUgSC48L2F1dGhvcj48YXV0aG9yPlNob2FtYW5lc2gsIEFzaGthbjwvYXV0aG9yPjxhdXRo

b3I+RHJlc3NlciwgR2VvcmdlIEsuPC9hdXRob3I+PGF1dGhvcj5IYW1ldCwgUGF2ZWw8L2F1dGhv

cj48YXV0aG9yPkhlcm1hbiwgUm9iZXJ0IEouPC9hdXRob3I+PGF1dGhvcj5CdXJnZXNzLCBFbGxl

bjwvYXV0aG9yPjxhdXRob3I+R3J5biwgU3RldmVuIEUuPC9hdXRob3I+PGF1dGhvcj5HcsOpZ29p

cmUsIEplYW4gQy48L2F1dGhvcj48YXV0aG9yPkxld2FuY3p1aywgUmljaGFyZDwvYXV0aG9yPjxh

dXRob3I+UG9pcmllciwgTHVjPC9hdXRob3I+PGF1dGhvcj5DYW1wYmVsbCwgVGF2aXMgUy48L2F1

dGhvcj48YXV0aG9yPkZlbGRtYW4sIFJvc3MgRC48L2F1dGhvcj48YXV0aG9yPkxhdm9pZSwgS2lt

IEwuPC9hdXRob3I+PGF1dGhvcj5Uc3V5dWtpLCBSb3NzIFQuPC9hdXRob3I+PGF1dGhvcj5Ib25v

cywgR2VvcmdlPC9hdXRob3I+PGF1dGhvcj5QcmVidGFuaSwgQWxseSBQLiBILjwvYXV0aG9yPjxh

dXRob3I+S2xpbmUsIEdyZWdvcnk8L2F1dGhvcj48YXV0aG9yPlNjaGlmZnJpbiwgRXJuZXN0byBM

LjwvYXV0aG9yPjxhdXRob3I+RG9uLVdhdWNob3BlLCBBbmRyZXc8L2F1dGhvcj48YXV0aG9yPlRv

YmUsIFNoZWxkb24gVy48L2F1dGhvcj48YXV0aG9yPkdpbGJlcnQsIFJpY2hhcmQgRS48L2F1dGhv

cj48YXV0aG9yPkxlaXRlciwgTGF3cmVuY2UgQS48L2F1dGhvcj48YXV0aG9yPkpvbmVzLCBDaGFy

bG90dGU8L2F1dGhvcj48YXV0aG9yPldvbywgVmluY2VudDwvYXV0aG9yPjxhdXRob3I+SGVnZWxl

LCBSb2JlcnQgQS48L2F1dGhvcj48YXV0aG9yPlNlbGJ5LCBQZXRlcjwvYXV0aG9yPjxhdXRob3I+

UGlwZSwgQW5kcmV3PC9hdXRob3I+PGF1dGhvcj5NY0ZhcmxhbmUsIFBoaWxpcCBBLjwvYXV0aG9y

PjxhdXRob3I+T2gsIFBhdWw8L2F1dGhvcj48YXV0aG9yPkd1cHRhLCBNaWxhbjwvYXV0aG9yPjxh

dXRob3I+QmFjb24sIFNpbW9uIEwuPC9hdXRob3I+PGF1dGhvcj5LYWN6b3Jvd3NraSwgSmFudXN6

PC9hdXRob3I+PGF1dGhvcj5UcnVkZWF1LCBMdWM8L2F1dGhvcj48YXV0aG9yPkNhbXBiZWxsLCBO

b3JtYW4gUi4gQy48L2F1dGhvcj48YXV0aG9yPkhpcmVtYXRoLCBTd2FwbmlsPC9hdXRob3I+PGF1

dGhvcj5Sb2VyZWNrZSwgTWljaGFlbDwvYXV0aG9yPjxhdXRob3I+QXJjYW5kLCBKb2FubmU8L2F1

dGhvcj48YXV0aG9yPlJ1emlja2EsIE1hcmNlbDwvYXV0aG9yPjxhdXRob3I+UHJhc2FkLCBHLiBW

LiBSYW1lc2g8L2F1dGhvcj48YXV0aG9yPlZhbGzDqWUsIE1pY2hlbDwvYXV0aG9yPjxhdXRob3I+

RWR3YXJkcywgQ2VkcmljPC9hdXRob3I+PGF1dGhvcj5TaXZhcGFsYW4sIFByYXZlZW5hPC9hdXRo

b3I+PGF1dGhvcj5QZW5uZXIsIFMuIEJyaWFuPC9hdXRob3I+PGF1dGhvcj5Gb3VybmllciwgQW5u

ZTwvYXV0aG9yPjxhdXRob3I+QmVub2l0LCBHZW5ldmnDqHZlPC9hdXRob3I+PGF1dGhvcj5GZWJl

ciwgSmFudXN6PC9hdXRob3I+PGF1dGhvcj5EaW9ubmUsIEphbmlzPC9hdXRob3I+PGF1dGhvcj5N

YWdlZSwgTGF1cmEgQS48L2F1dGhvcj48YXV0aG9yPkxvZ2FuLCBBbGV4YW5kZXIgRy48L2F1dGhv

cj48YXV0aG9yPkPDtHTDqSwgQW5uZS1NYXJpZTwvYXV0aG9yPjxhdXRob3I+UmV5LCBFdmVseW5l

PC9hdXRob3I+PGF1dGhvcj5GaXJveiwgVGFiYXNzdW08L2F1dGhvcj48YXV0aG9yPkt1eXBlciwg

TGF1cmEgTS48L2F1dGhvcj48YXV0aG9yPkdhYm9yLCBKb25hdGhhbiBZLjwvYXV0aG9yPjxhdXRo

b3I+VG93bnNlbmQsIFJheW1vbmQgUi48L2F1dGhvcj48YXV0aG9yPlJhYmksIERvcmVlbiBNLjwv

YXV0aG9yPjxhdXRob3I+RGFza2Fsb3BvdWxvdSwgU3RlbGxhIFMuPC9hdXRob3I+PC9hdXRob3Jz

PjwvY29udHJpYnV0b3JzPjx0aXRsZXM+PHRpdGxlPkh5cGVydGVuc2lvbiBDYW5hZGEmYXBvcztz

IDIwMTggR3VpZGVsaW5lcyBmb3IgRGlhZ25vc2lzLCBSaXNrIEFzc2Vzc21lbnQsIFByZXZlbnRp

b24sIGFuZCBUcmVhdG1lbnQgb2YgSHlwZXJ0ZW5zaW9uIGluIEFkdWx0cyBhbmQgQ2hpbGRyZW48

L3RpdGxlPjxzZWNvbmRhcnktdGl0bGU+Q2FuYWRpYW4gSm91cm5hbCBvZiBDYXJkaW9sb2d5PC9z

ZWNvbmRhcnktdGl0bGU+PC90aXRsZXM+PHBlcmlvZGljYWw+PGZ1bGwtdGl0bGU+Q2FuYWRpYW4g

Sm91cm5hbCBvZiBDYXJkaW9sb2d5PC9mdWxsLXRpdGxlPjwvcGVyaW9kaWNhbD48cGFnZXM+NTA2

LTUyNTwvcGFnZXM+PHZvbHVtZT4zNDwvdm9sdW1lPjxudW1iZXI+NTwvbnVtYmVyPjxkYXRlcz48

eWVhcj4yMDE4PC95ZWFyPjwvZGF0ZXM+PHB1Ymxpc2hlcj5FbHNldmllcjwvcHVibGlzaGVyPjxp

c2JuPjA4MjgtMjgyWDwvaXNibj48dXJscz48cmVsYXRlZC11cmxzPjx1cmw+aHR0cHM6Ly9kb2ku

b3JnLzEwLjEwMTYvai5jamNhLjIwMTguMDIuMDIyPC91cmw+PC9yZWxhdGVkLXVybHM+PC91cmxz

PjxlbGVjdHJvbmljLXJlc291cmNlLW51bT4xMC4xMDE2L2ouY2pjYS4yMDE4LjAyLjAyMjwvZWxl

Y3Ryb25pYy1yZXNvdXJjZS1udW0+PGFjY2Vzcy1kYXRlPjIwMTkvMDcvMjg8L2FjY2Vzcy1kYXRl

PjwvcmVjb3JkPjwvQ2l0ZT48L0VuZE5vdGU+AG==

ADDIN EN.CITE.DATA (7). It is recognized that the lower blood pressure targets can be difficult to achieve, especially in older patients with complex comorbidity, and that therapeutic targets require individualization based on informed patient preferences. Some patients may not tolerate intensive management of blood pressure or decline treatment even with adequate education.? Efforts should be considered to find the most tolerable and preferred interventions to reduce risk, when possible. Using a simple diagnostic and treatment algorithm has been shown to achieve hypertension control rates as high as 90%, when paired with a hypertension registry with performance reporting ADDIN EN.CITE <EndNote><Cite><Author>Jaffe</Author><Year>2016</Year><RecNum>7329</RecNum><DisplayText>(8)</DisplayText><record><rec-number>7329</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1517951607" guid="bbb38195-01fb-4b72-ac7b-6d1c675471bd">7329</key><key app="ENWeb" db-id="">0</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Jaffe, M. G.</author><author>Young, J. D.</author></authors></contributors><auth-address>Department of Endocrinology, Kaiser Permanente South San Francisco Medical Center, South San Francisco, CA.&#xD;Department of Medicine, Kaiser Permanente Oakland Medical Center, Oakland, CA.</auth-address><titles><title>The Kaiser Permanente Northern California Story: Improving Hypertension Control From 44% to 90% in 13 Years (2000 to 2013)</title><secondary-title>J Clin Hypertens (Greenwich)</secondary-title><alt-title>Journal of clinical hypertension (Greenwich, Conn.)</alt-title></titles><periodical><full-title>J Clin Hypertens (Greenwich)</full-title></periodical><pages>260-1</pages><volume>18</volume><number>4</number><edition>2016/03/05</edition><keywords><keyword>California/epidemiology</keyword><keyword>Delivery of Health Care/*standards</keyword><keyword>Diagnostic Techniques, Cardiovascular/*standards</keyword><keyword>*Disease Management</keyword><keyword>Humans</keyword><keyword>*Hypertension/diagnosis/epidemiology/therapy</keyword><keyword>*Managed Care Programs/standards</keyword><keyword>Morbidity/trends</keyword><keyword>*Registries</keyword><keyword>Retrospective Studies</keyword></keywords><dates><year>2016</year><pub-dates><date>Apr</date></pub-dates></dates><isbn>1524-6175</isbn><accession-num>26939059</accession-num><label>7549</label><urls></urls><electronic-resource-num>10.1111/jch.12803</electronic-resource-num><remote-database-provider>NLM</remote-database-provider><language>eng</language></record></Cite></EndNote>(8)**. Using both a simple hypertension management algorithm and a registry with performance reporting have become an international standard of practice for hypertension management but has not yet become a common practice in Canada ADDIN EN.CITE <EndNote><Cite><Author>World Health Organization</Author><Year> 2018 (WHO/NMH/NVI/18.14). Licence: CC BY-NC-SA 3.0 IGO.</Year><RecNum>7453</RecNum><DisplayText>(9)</DisplayText><record><rec-number>7453</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1555942279" guid="18de8b53-bdff-47e9-affd-9530dac03beb">7453</key><key app="ENWeb" db-id="">0</key></foreign-keys><ref-type name="Report">27</ref-type><contributors><authors><author>World Health Organization,</author></authors><tertiary-authors><author>World Health Organization,</author></tertiary-authors></contributors><titles><title>HEARTS Technical package for cardiovascular disease management in primary health care: Implementation guide</title></titles><pages>1-30</pages><dates><year> 2018 (WHO/NMH/NVI/18.14). Licence: CC BY-NC-SA 3.0 IGO.</year></dates><pub-location>Geneva, Switzerland</pub-location><label>7673</label><urls></urls></record></Cite></EndNote>(9). Samples of simple algorithms and implementation resources can be found at in the resource section. A free stand-alone smart phone-based hypertension registry is also available in the resource section (). We also advocate for the use of electronic medical records that provide registry reporting functions**. It is critical for the federal, provincial and territorial governments to take a well planned strategic public health approach to the prevention and control of hypertension and to collaborate with the health and scientific sector on monitoring and evaluation and implementation. * A low proportion of women aged 60 and above will be at low cardiovascular risk (<10% risk of a cardiovascular event in 10 years) where lifestyle management would be a primary therapy.** regular performance reporting is recommended to include the number of people diagnosed with hypertension as a % of the number estimated to have hypertension in the clinical practice, the % treated with antihypertensive therapy and the % controlled. Other important features can include identification and recall for those missing appointments and those without a recent blood pressure assessment. Table: Critical steps to control hypertension.1. Correctly measure blood pressure routinely in all adults and especially older women.2. Treat people with hypertension with antihypertensive drugs to achieve control*. 3. Consider initiating treatment at a systolic blood pressure of > 130 mmHg and lowering the systolic blood pressure to < 120 mm Hg in those at high cardiovascular risk (e.g., Framingham risk score of > 15%, or men or women aged 75 years or higher), to optimize risk reduction. Persons with diabetes should have a blood pressure treatment threshold of 130/80 mm Hg and target of < 130/80 mm Hg.4. Use validated automated blood pressure devices, where feasible home blood pressure measurement and 24 hr ambulatory blood pressure measurement. For a systolic target <120 mmHg consider automated devices that operate without an observer present and that take and average multiple readings. 5. Use standardized treatment protocols 6. Use registries with performance reporting to enhances hypertension control**. RESOURCE SECTIONHypertension management algorithms guide for a hypertension control program a hypertension management algorithm Simple Hypertension registry ADDIN EN.REFLIST 1.Institute for Health Metrics and Evaluation 2020;Pages on March 25 2020.2.Campbell NRC, Schutte AE, Varghese CV, Ordunez P, Zhang X-H, Khan T, et al. S?o Paulo call to action for the prevention and control of high blood pressure: 2020. The Journal of Clinical Hypertension. 2019;21(12):1744-52.3.Campbell NR, Brant R, Johansen H, Walker RL, Wielgosz A, Onysko J, et al. Increases in antihypertensive prescriptions and reductions in cardiovascular events in Canada. Hypertension. 2009;53(2):128-34.4.Leung AA, Williams JVA, McAlister FA, Campbell NRC, Padwal RS, Tran K, et al. Worsening Hypertension Awareness, Treatment, and Control Rates in Canadian Women Between 2007 and 2017. Canadian Journal of Cardiology.5.Zhou B, Danaei G, Stevens GA, Bixby H, Taddei C, Carrillo-Larco RM, et al. Long-term and recent trends in hypertension awareness, treatment, and control in 12 high-income countries: an analysis of 123 nationally representative surveys. The Lancet.6.Wilkins K, Gee M, Campbell N. The difference in hypertension control between older men and women. Health Reports. 2012;23:3-10.7.Nerenberg KA, Zarnke KB, Leung AA, Dasgupta K, Butalia S, McBrien K, et al. Hypertension Canada's 2018 Guidelines for Diagnosis, Risk Assessment, Prevention, and Treatment of Hypertension in Adults and Children. Canadian Journal of Cardiology. 2018;34(5):506-25.8.Jaffe MG, Young JD. The Kaiser Permanente Northern California Story: Improving Hypertension Control From 44% to 90% in 13 Years (2000 to 2013). J Clin Hypertens (Greenwich). 2016;18(4):260-1.9.World Health Organization. HEARTS Technical package for cardiovascular disease management in primary health care: Implementation guide. Geneva, Switzerland; 2018 (WHO/NMH/NVI/18.14). Licence: CC BY-NC-SA 3.0 IGO.:1-30.Figure 1. Hypertension awareness, treatment and control rates in Canadian women from 2007 to 2017The data are from the Canadian Health Measures Surveys ADDIN EN.CITE <EndNote><Cite><Author>Leung</Author><RecNum>7624</RecNum><DisplayText>(4)</DisplayText><record><rec-number>7624</rec-number><foreign-keys><key app="EN" db-id="t0fzap5t0p2wrcev2el5ftz5vtpwvsfs500z" timestamp="1586890772" guid="186b4b5d-4e42-48e4-bdd0-714631eda64d">7624</key></foreign-keys><ref-type name="Journal Article">17</ref-type><contributors><authors><author>Leung, Alexander A.</author><author>Williams, Jeanne V. A.</author><author>McAlister, Finlay A.</author><author>Campbell, Norman R. C.</author><author>Padwal, Raj S.</author><author>Tran, Karen</author><author>Tsuyuki, Ross</author><author>McAlister, Finlay A.</author><author>Campbell, Norman R. C.</author><author>Khan, Nadia</author><author>Padwal, Raj</author><author>Quan, Hude</author><author>Leung, Alexander A.</author></authors></contributors><titles><title>Worsening Hypertension Awareness, Treatment, and Control Rates in Canadian Women Between 2007 and 2017</title><secondary-title>Canadian Journal of Cardiology</secondary-title></titles><periodical><full-title>Canadian Journal of Cardiology</full-title></periodical><dates></dates><publisher>Elsevier</publisher><isbn>0828-282X</isbn><urls><related-urls><url>;(4). Figure 2a: Cardiovascular (total, ischemic heart disease and stroke) death rate per 100,000 population in Canada 1990-2017.The data show changes in the rate of cardiovascular disease (total, ischemic heart disease and stroke) deaths per 100,000 in Canada from 1990 to 2017 using data from the Global Burden of Disease Study 2017. Global Burden of Disease Study 2017 (GBD 2017) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2018. Available from 2b: Age standardized cardiovascular (total, ischemic heart disease and stroke) death rate per 100,000 population in Canada 1990-2017 The data show changes in the rate of age-standardized cardiovascular disease (total, ischemic heart disease and stroke) deaths in Canada from 1990 to 2017 using data from the Global Burden of Disease Study 2017. Global Burden of Disease Study 2017 (GBD 2017) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2018. Available from 2c: Disability adjusted life years due to cardiovascular disease in Canada. The data show changes in disability adjusted life years (DALYS) due to cardiovascular disease in Canada from 1990 to 2017 using data from the Global Burden of Disease Study 2017. Global Burden of Disease Study 2017 (GBD 2017) Results. Seattle, United States: Institute for Health Metrics and Evaluation (IHME), 2018. Available from . ................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download