Centers for Disease Control and Prevention
Ecallantide is a recombinant protein produced in Pichia pastoris (P pastoris) yeast cells. It is a selective, reversible inhibitor of plasma kallikrein that binds to kallikrein, decreasing the conversion of HMW kininogen to bradykinin, reducing the symptoms of acute HAE.1 . Pharmacokinetic Parameters AUC (ng*hr/mL) Cmax (ng/mL) Tmax (hrs) CL ................
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