OPIOID CONVERSION GUIDE
OPIOID CONVERSION GUIDE
These conversions are a guide only. Patients may vary in their response to different opioids. After changing opioid, close assessment should follow and the dose altered as necessary.
Equianalgesic doses of oral opioids
Oral opioid
morphine hydromorphone oxycodone codeine tapentadol tramadol
Conversion factor (opioid dose x or ? by factor
= morphine dose)
x 5 x 1.5 ? 8 ? 3 ? 5
Practical equianalgesic
dose 10 mg
2 mg 5-7.5 mg* 75-90 mg*
50 mg* 50 mg
* dose guided by strength of medication available
Methadone conversions are complicated and prescribing should be restricted to medical
specialists with experience of methadone prescribing for pain management.
Subcutaneous route conversions
Opioid
morphine hydromorphone
Oral dose
30 mg 6 mg
Equianalgesic subcutaneous
dose 10 mg
2 mg
Conversion factor
(oral dose ? by factor = subcut dose)
? 3 ? 3
Transdermal preparation conversions
Opioid
buprenorphine fentanyl
Patch strength
5 microgram/hr 12 microgram/hr
Equianalgesic oral morphine dose 12 mg/24 hrs
30-45 mg/24 hrs
Sublingual preparation conversions
Opioid buprenorphine tablet fentanyl lozenge
Dose 200 microgram 200 microgram
Equianalgesic oral morphine dose for pain 8-16 mg
no direct conversion initiate 200 microgram lozenge
and titrate to effect
September 2015
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