Cdn-links.lww.com



Supplementary DocumentsTable E1. ICD-9-CM codes used to define the cohort of elective procedures defined by the inclusion criteria.SurgeryICD-9-CM codeLumpectomy8520, 8521, 8522, 8523Mastectomy'8541' '8542' '8543' '8544' '8545' '8546' '8547' '8548'Coronary Artery Bypass Graft'3610' '3611' '3612' '3613' '3614' '3615' '3616' '3617' '3619' '362' '363' '3631' '3632' '3633' '3634' '3639'Caesarian section'740' '741' '742' '744' '7499'Cholecystectomy'5121' '5122' '5123' '5124' '5141' '5142' '5143' '5149' '5151' '5159'Colectomy'1731' '1732' '1733' '1734' '1735' '1736' '1739' '4571'4572' '4573' '4574' '4575' '4576' '4579' '458' '4581' '4582' '4583' '4840' '4841' '4842' '4843' '4849' '485' '4850' '4851' '4852' '4859' '4861' '4862' '4863' '4864' '4865' '4866' '4869'Total Hip Replacement'0070' '0071' '0072' '0073' '0074' '0075' '0076' '0077' '0085' '0086' '0087' '8151' '8152' '8153' '8169'Hysterectomy'683' '6831' '6839' '684' '6841' '6849' '685' '6851' '6859' '686' '6861' '6869' '687' '6871' '6879' '689'Hernia Repair'1711' '1712' '1713' '1721' '1722' '1723' '1724' '5300' '5301' '5302' '5303' '5304' '5305' '5310' '5311' '5312' '5313' '5314' '5315' '5316' '5317' '5321' '5329' '5331' '5339''1711' '1712' '1713' '1721' '1722' '1723' '1724' '5300' '5301' '5302' '5303' '5304' '5305' '5310' '5311' '5312' '5313' '5314' '5315' '5316' '5317' '5321' '5329' '5331' '5339'Total Knee Replacement'0080' '0081' '0082' '0083' '0084' '8141' '8142' '8143' '8144' '8146' '8147' '8154' '8155'Laminectomy'0302' '0309' '805' '8050' '8051' '8059' '8459' '8460' '8461' '8462' '8463' '8464' '8465' '8466' '8467' '8468' '8469' '8480' '8481' '8482' '8483' '8484' '8485'Elective Spine Surgeries'8100' '8101' '8102' '8103' '8104' '8105' '8106' '8107' '8108' '8109' '8130' '8131' '8132' '8133' '8134' '8135' '8136' '8137' '8138' '8139' '8161' '8162' '8163' '8164' '8451')Table E2. ICD-9-CM codes used to define the individual components of the composite outcome.Post-operative outcomeICD-9-CM codeAcute Kidney Injury"5845 "5846 " "5847 "5848 " "5849 ""586 " "9975Respiratory Failure"51851" "51853" "51881 "51884"9670" "9672 "9671" "9604Venous Thromboembolism"45111" "45119" "4512 "45181" "4519 "45340" "45341" "4538 "45394151 "41511" "41513" "41519"Sepsis"0380 "0381 "03810” "03811" "03812""03819" "0382 “ "0383 " "03840" "03841" "03842" "03843" "03844" "03849" "0388 " "0389 " "78552" "99591" "99592" "9980 "99802"Acute Myocardial Infarction‘41000’ ‘41001’ ‘41010’ ‘41011’ ‘41020’ ‘41021’ ‘41030’ ‘41031’ ‘41040’ ‘41041’ ‘41050’ ‘41051’ ‘41060’ ‘41061’ ‘41070’ ‘41071’ ‘41080’ ‘41081’ ‘41090’ ‘41091’Acute Cerebrovascular Accident430 ‘431’ ‘4320’ ‘4321’ ‘4329’ ‘43301’ ‘43311’ ‘43321’ ‘43331’ ‘43381’ ‘43391’ ‘43401’ ‘43411’ ‘43491’Table E3. ICD-9-CM and Clinical Classification Software codes used to define covariates.CovariateICD-9-CM CodeSubstance Use Disorders'2920 ' '29211' '29212' '2922 ' '29281' '29282' '29283' '29284' '29285' '29289' '2929 ' '30400' '30401' '30402' '30403' '30410' '30411' '30412' '30413' '30420' '30421' '30422' '30423' '30440' '30441' '30442' '30443' '30450' '30451' '30452' '30453' '30460' '30461' '30462' '30463' '30470' '30471' '30472' '30473' '30480' '30481' '30482' '30483' '30490' '30491''30492' '30493' '30530' '30531' '30532' '30533' '30540' '30541' '30542' '30543' '30550' '30551' '30552' '30553' '30560' '30561' '30562' '30563' '30570' '30571' '30572' '30573' '30580' '30581' '30582' '30583' '30590' '30591' '30592' '30593' '64830' '64831' '64832' '64833' '64834' '96500' '96501' '96502' '96509' 'V6542Smoking'V1582 ' '3051Chronic Pain'3380 ' '33821' '33822' '33828' '33829' '3384Obesity'27800' '27801' '27802' '27803COPDCCS 127Liver DiseaseCCS 151 16, 6Alcohol UseCCS 660Mood DisorderCCS 657Solid TumourCCS '11' '12' '13''14' '15' '16' '17' '18' '19' '20' '21''24' '25' '26' '27' '28' '29' '30' '31' '32' '33' '34' '35' '36' '41' '43' '44')Hematologic MalignancyCCS '37' '38' '39' '40' '41'Metastatic CancerCCS 42DiabetesCCS 49, 50Coronary Artery DiseaseCCS 101Renal DiseaseCCS 158AsthmaCCS 202History of Stroke or TIACCS 113Rheumatoid ArthiritisCCS 202History of Congestive Heart FailureCCS 108Personality DisorderCCS 658Schizophrenic DisorderCCS 659Abbreviations: CCS, Clinical Classification SoftwareTable E4. Analysis Examining the Association Between Patients with active Cannabis Use Disorder and the Primary and Secondary Outcomes in the un-matched cohort with the use of survey weights.Cannabis Use Disorder(N=67,828)No Cannabis Use Disorder(N=20,565,798)Odds Ratio or Estimated Difference (95% CI)(Cannabis Use Disorder vs. No Cannabis Use Disorder)P-valuePrimary Composite Outcome(%)1420 (2.1)469,819 (2.3)0.916 (0.817, 1.027)0.135Acute Myocardial Infarction(%)281 (0.4)45984 (0.2)1.856 (1.458, 2.364)<0.001Respiratory Failure(%)452 (0.7)167,544 (0.8)0.818 (0.681, 0.982)0.031Acute Kidney Injury(%)671 (1.0)238,442 (1.2)0.853 (0.725, 1.003)0.055VTE (%)140 (0.2)48,215 (0.2)0.880 (0.597, 1.298)0.519Sepsis (%)163 (0.2)59,624 (0.3)0.831 (0.611, 1.130)0.237CVA (%)60 (0.1)12604 (0.1)1.441 (0.882, 2.353)0.144Mortality (%)50 (0.1)17509 (0.1)0.872 (0.488, 1.558)0.643Length of Stay, Days (95% CI)3.16 (3.11, 3.21)3.29(3.24, 3.34)-0.13 (-0.19, -0.07)<0.001Total Cost (USD)(95% CI)12425 (12215, 12635)12492 (12282, 12702)-67 (-148, 144)0.534Abbreviations: VTE=Venous Thromboembolism, CVA=Cerebrovascular Accident, SD = Standard Deviation, USD=United States Dollars. Cell Sites </=10 cannot be published as per the data use agreement of the Nationwide Inpatient Sample. Significance defined as P<0.05 for the composite outcome and P<0.005 for the components of the composite outcome and secondary outcome. Results were obtained using regression models after adjusting for confounders ................
................

In order to avoid copyright disputes, this page is only a partial summary.

Google Online Preview   Download