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AppendixAppendix 1: ICD-10-CM diagnosis codes for wound complicationsCodeDescriptionCategoryT81.4XXAInfection following a procedure, initial encounterSSIT81.4XXDInfection following a procedure, subsequent encounterSSIT81.4XXSInfection following a procedure, sequelaSSIT81.40XAInfection following a procedure, unspecified, initial encounterSSIT81.40XDInfection following a procedure, unspecified, subsequent encounterSSIT81.40XSInfection following a procedure, unspecified, sequelaSSIT81.41XAInfection following a procedure, superficial incisional surgical site, initial encounterSSIT81.41XDInfection following a procedure, superficial incisional surgical site, subsequent encounterSSIT81.41XSInfection following a procedure, superficial incisional surgical site, sequelaSSIT81.42XAInfection following a procedure, deep incisional surgical site, initial encounterSSIT81.42XDInfection following a procedure, deep incisional surgical site, subsequent encounterSSIT81.42XSInfection following a procedure, deep incisional surgical site, sequelaSSIT81.43XAInfection following a procedure, organ and space surgical site, initial encounterSSIT81.43XDInfection following a procedure, organ and space surgical site, subsequent encounterSSIT81.43XSInfection following a procedure, organ and space surgical site, sequelaSSIT81.49XAInfection following a procedure, other surgical site, initial encounterSSIT81.49XDInfection following a procedure, other surgical site, subsequent encounterSSIT81.49XSInfection following a procedure, other surgical site, sequelaSSIT81.30XADisruption of wound, unspecified, initial encounterWound dehiscenceT81.30XDDisruption of wound, unspecified, subsequent encounterWound dehiscenceT81.30XSDisruption of wound, unspecified, sequelaWound dehiscenceT81.31XADisruption of external operation (surgical) wound, not elsewhere classified, initial encounterWound dehiscenceT81.31XDDisruption of external operation (surgical) wound, not elsewhere classified, subsequent encounterWound dehiscenceT81.31XSDisruption of external operation (surgical) wound, not elsewhere classified, sequelaWound dehiscenceT81.32XADisruption of internal operation (surgical) wound, not elsewhere classified, initial encounterWound dehiscenceT81.32XDDisruption of internal operation (surgical) wound, not elsewhere classified, subsequent encounterWound dehiscenceT81.32XSDisruption of internal operation (surgical) wound, not elsewhere classified, sequelaWound dehiscenceL02.212Cutaneous abscess of back [any part, except buttock]Cellulitis/abscessL02.219Cutaneous abscess of trunk, unspecifiedCellulitis/abscessL02.818Cutaneous abscess of other sitesCellulitis/abscessL02.91Cutaneous abscess, unspecifiedCellulitis/abscessL03.312Cellulitis of back [any part except buttock]Cellulitis/abscessL03.319Cellulitis of trunk, unspecifiedCellulitis/abscessL03.818Cellulitis of other sitesCellulitis/abscessL03.90Cellulitis, unspecifiedCellulitis/abscessT81.89XAOther complications of procedures, not elsewhere classified, initial encounter (granuloma)Other wound complicationT81.89XDOther complications of procedures, not elsewhere classified, subsequent encounter (granuloma)Other wound complicationT81.89XSOther complications of procedures, not elsewhere classified, sequela (granuloma)Other wound complicationAbbreviations: SSI, Surgical site infection.APPENDIXAppendix 2: All wound complication, surgical site infections, and wound dehiscence during index and follow-up time periods after open sigmoidectomy using SSPPWound complicationsOverallAdmission typeElectiveNon-electiveN%N%N%Wound complications at indexALL333100.022266.711133.3All wound complications103.062.743.6SSI92.752.343.6Wound dehiscence10.310.5-0.0Abscess/cellulitis/granuloma10.310.5-0.0Wound complications during index and 30-day follow-upALLa327100.021967.010833.0All wound complications206.1115.098.3SSI175.294.187.4Wound dehiscence30.920.910.9Abscess/cellulitis/granuloma20.610.510.9a Based on patients with an index admission to a hospital that continued to contribute data for at least 30 days after dischargeAbbreviations: SSI, Surgical site infection; SSPP, STRATAFIXTM Symmetric PDSTM Plus Knotless Tissue Control DeviceAPPENDIXAppendix 3: Economic and healthcare resource utilization outcomes of open sigmoidectomy using SSPPVariablesOverall(N = 333)Admission typeElective(N = 222)Non-elective(N = 111)Operating room time (mins)Mean (SD)191.2 (66.8)188.2 (64.9)199.3 (70.3)Median180.0180.0195.0Length of stay (days)Mean (SD)7.6 (13.9)4.0 (3.8)14.8 (21.9)Median4.03.011.0Operating room costMean (SD)$10,045 ($3,204)$10,094 ($2,606)$9,946 ($4,163)Median$10,040$10,047$9,847Supply costMean (SD)$3,602 ($1,704)$3,225 ($1,503)$3,406 ($2,019)Median$3,261$3,225$3,406Room and board costMean (SD)$9,9484 ($22,007)$4,654 ($5,090)$19,145 ($35,616)Median$4,644$3,311$11,639Total hospital costMean (SD)$30,868 ($47,071)$21,560 ($10,273)$49,483 ($77,141)Median$21,615$19,130$34,559All cause readmission, N (%)30-day readmissiona68 (11.8)33 (8.8)35 (17.2)60-day readmissionb95 (16.9)49 (13.4)46 (23.3)90-day readmissionc116 (21.1)58 (16.2)58 (30.1)a Based on 327 patients: 219 in elective group and 108 in non-elective groupb Based on 316 patients: 211 in elective group and 105 in non-elective groupc Based on 307 patients: 204 in elective group and 103 in non-elective groupAbbreviations: SD, Standard deviation; SSPP, STRATAFIXTM Symmetric PDSTM Plus Knotless Tissue Control DeviceAPPENDIXAppendix 4: Primary diagnoses and procedures for 30-day readmissions after open colorectal procedures using SSPPICD codeDescriptionOverall readmissionsElective readmissionsNonelective readmissionsN%N%N%ALL844143PRIMARY DIAGNOSESGastrointestinal and infection-related primary diagnosesK56.60Unspecified intestinal obstruction11.212.400K56.609Unspecified intestinal obstruction, unspecified as to partial versus complete obstruction22.424.900.0K56.69Other intestinal obstruction11.212.400.0K57.32Diverticulitis of large intestine without perforation or abscess without bleeding22.412.412.3K61.1Rectal abscess11.212.400.0K62.5Hemorrhage of anus and rectum11.200.012.3K63.0Abscess of intestine11.212.400.0K63.2Fistula of intestine11.212.400.0K65.1Peritoneal abscess22.412.412.3K68.11Postprocedural retroperitoneal abscess11.200.012.3K85.30Drug induced acute pancreatitis without necrosis or infection11.212.400.0K91.0Vomiting following gastrointestinal surgery11.212.400.0K91.3Postprocedural intestinal obstruction11.212.400.0K91.81Other intraoperative complications of digestive system11.212.400.0K91.870Postprocedural hematoma of a digestive system organ or structure following a digestive system procedure11.212.400.0K91.872Postprocedural seroma of a digestive system organ or structure following a digestive system procedure11.212.400.0K91.89Other postprocedural complications and disorders of digestive system22.412.412.3K92.2Gastrointestinal hemorrhage, unspecified11.200.012.3K94.13Enterostomy malfunction11.212.400.0K94.19Other complications of enterostomy11.212.400.0T81.31XADisruption of external operation (surgical) wound, not elsewhere classified, initial encounter11.200.012.3T81.43XAInfection following a procedure, organ and space surgical site, initial encounter11.200.012.3T81.49XAInfection following a procedure, other surgical site, initial encounter22.400.024.7T81.4XXAInfection following a procedure, initial encounter1315.5819.5511.6T81.89XAOther complications of procedures, not elsewhere classified, initial encounter11.200.012.3Other primary diagnosesA04.7Enterocolitis due to Clostridium difficile11.212.400.0A04.72Enterocolitis due to Clostridium difficile, not specified as recurrent67.137.337.0A41.51Sepsis due to Escherichia coli [E. coli]11.212.400.0A41.9Sepsis, unspecified organism78.324.9511.6C16.9Malignant neoplasm of stomach, unspecified11.200.012.3C18.7Malignant neoplasm of sigmoid colon11.200.012.3C78.7Secondary malignant neoplasm of liver and intrahepatic bile duct11.212.400.0C79.11Secondary malignant neoplasm of bladder11.200.012.3C83.39Diffuse large B-cell lymphoma, extranodal and solid organ sites11.200.012.3D64.9Anemia, unspecified11.200.012.3G89.18Other acute postprocedural pain11.200.012.3I21.4Non-ST elevation (NSTEMI) myocardial infarction11.212.400.0I46.9Cardiac arrest, cause unspecified11.200.012.3I48.0Paroxysmal atrial fibrillation11.200.012.3I81Portal vein thrombosis11.200.012.3I82.421Acute embolism and thrombosis of right iliac vein11.200.012.3J90Pleural effusion, not elsewhere classified11.200.012.3J96.22Acute and chronic respiratory failure with hypercapnia11.200.012.3N17.9Acute kidney failure, unspecified67.149.824.7N32.1Vesicointestinal fistula11.200.012.3R10.9Unspecified abdominal pain22.412.412.3R53.81Other malaise22.400.024.7T80.219AUnspecified infection due to central venous catheter, initial encounter11.200.012.3Z43.2Encounter for attention to ileostomy11.212.400.0PRIMARY PROCEDURES0D1B0Z4Bypass Ileum to Cutaneous, Open Approach11.212.400.00DB80ZZExcision of Small Intestine, Open Approach11.212.400.00DQ98ZZRepair Duodenum, Via Natural or Artificial Opening Endoscopic11.212.400.00TBB8ZZExcision of Bladder, Via Natural or Artificial Opening Endoscopic11.200.012.302H633ZInsertion of Infusion Device into Right Atrium, Percutaneous Approach11.212.400.002HV33ZInsertion of Infusion Device into Superior Vena Cava, Percutaneous Approach33.612.424.70FT10ZZResection of Right Lobe Liver, Open Approach11.212.400.00W993ZXDrainage of Right Pleural Cavity, Percutaneous Approach, Diagnostic11.200.012.30W9B3ZZDrainage of Left Pleural Cavity, Percutaneous Approach11.200.012.30W9G30ZDrainage of Peritoneal Cavity with Drainage Device, Percutaneous Approach56.037.324.70W9J30ZDrainage of Pelvic Cavity with Drainage Device, Percutaneous Approach22.412.412.30W9J3ZZDrainage of Pelvic Cavity, Percutaneous Approach11.212.400.00W9L30ZDrainage of Lower Back with Drainage Device, Percutaneous Approach11.212.400.00WJG3ZZInspection of Peritoneal Cavity, Percutaneous Approach11.212.400.00WJP0ZZInspection of Gastrointestinal Tract, Open Approach11.212.400.030233N1Transfusion of Nonautologous Red Blood Cells into Peripheral Vein, Percutaneous Approach44.800.049.33E10X8ZIrrigation of Skin and Mucous Membranes using Irrigating Substance11.212.400.05A09557Assistance with Respiratory Ventilation, Greater than 96 Consecutive Hours, Continuous Positive Airway Pressure11.200.012.35A1C60ZPerformance of Biliary Filtration, Multiple11.200.012.35A1D60ZPerformance of Urinary Filtration, Multiple11.212.400.0D0004ZZBeam Radiation of Brain using Heavy Particles (Protons, Ions)11.200.012.3F07M3ZZMotor Function Treatment of Musculoskeletal System - Whole Body11.200.012.3F07M6ZZTherapeutic Exercise Treatment of Musculoskeletal System - Whole Body11.200.012.3Abbreviations: SSPP, STRATAFIXTM Symmetric PDSTM Plus Knotless Tissue Control DeviceAPPENDIXAppendix 5: Multivariable-adjusted comparison of wound complications in elective vs. non-elective open colorectal procedures using SSPPaOutcomeAORb95% CIp-valuebAdjusted OutcomescElectivecNon-electivecDifference95% CIcAll wound complicationsaDuring index1.9(0.54, 6.48)0.3243.9%2.4%1.5%(-0.01%, 0.05%)During index and 30-day follow-up1.1(0.62, 1.87)0.7937.1%6.7%0.3%(-0.02%, 0.03%)Surgical site infectionsDuring index2.2(0.52, 9.31)0.2813.9%2.1%1.8%(-0.01%, 0.05%)During index and 30-day follow-up1.3(0.45, 3.86)0.6066.4%5.2%1.2%(-0.03%, 0.06%)Abbreviations: AOR, Adjusted odds ratio; CI, Confidence interval; SSPP, STRATAFIXTM Symmetric PDSTM Plus Knotless Tissue Control DeviceaComplications is a composite endpoint consisting of surgical site infections, wound dehiscence, and other wound complications (abscess/cellulitis/granuloma)bAdjusted for demographic, procedural, and hospital/provider characteristicscMultivariable-adjusted outcomes based on marginal standardization method ................
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