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Apple Genomics Crossword

DIRECTIONS: Using the clues on the other side of this worksheet and the list of vocabulary words from the Apple Genomics website, fill in the crossword below. As an added challenge, you may try identifying the vocabulary word that goes with each clue before looking at the crossword puzzle.

Across

2. The portion of a plant that contains seeds.

4. One of four nucleic acids; complements guanine.

5. A discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA.

9. A small ring of DNA separate from the chromosome(s), found in prokaryotes and yeast.

10. An organic acid containing a carboxyl (-COOH) group and an amino (-NH2) group.

12. A large set of cloned DNA molecules spotted onto a solid matrix (such as a microscope slide) for use in probing a biological sample to determine gene expression, marker pattern or nucleotide sequence of DNA or RNA.

13. A structure within the nucleus of a eukaryotic cell where ribosomal RNA is made and assembled with proteins to make ribosomal subunits.

17. An enzyme that is essential for DNA replication and that catalyzes the covalent bonding of adjacent DNA nucleotides; used in genetic engineering to paste a specific piece of into a vector.

19. A cooperative unit of many similar cells that perform a specific function within a multi-cellular organism.

20. A protein that serves as a biological catalyst, changing the rate of a chemical reaction without itself being changed into a different molecule in the process.

Down

1. A discipline that uses knowledge of hereditary biochemistry to alter the genetic makeup of living things.

3. To form base pairs between complementary regions of two strands of DNA that were not originally paired.

6. In eukaryotes, a non-expressed (non-coding) portion of a gene that is excised from RNA.

7. The synthesis of a polypeptide using the genetic information encoded in an mRNA molecule.

8. Enzyme that catalyzes the synthesis of nucleic acids on preexisting nucleic acid templates, assembling RNA from ribonucleotides or DNA from deoxyribonucleotides.

11. An apparatus consisting essentially of a compartment spun about a central axis to separate colloidal particles suspended in a liquid.

14. A cell organelle consisting of RNA and protein organized into two subunits and functioning as the site of protein synthesis in the cytoplasm.

15. A disease-causing organism.

16. A piece of DNA, usually a bacterial plasmid or a viral genome, that is used to move genes from one cell to another.

18. Single-celled prokaryotes with a single chromosome, multiple plasmids, and no cellular organelles.

Apple Genomics Crossword KEY

Across

2. Fruit

4. Cytosine

5. Gene

9. Plasmid

10. Amino

12. Microarray

13. Nucleolus

17. Ligase

19. Tissue

20. Enzyme

Down

1. Biotechnology

3. Hybridize

6. Intron

7. Translation

8. Polymerase

11. Centrifuge

14. Ribosome

15. Pathogen

16. Vector

18. Bacteria

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