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WLC protocol was similar among included studies and applied on suspicious lesions. SSY and FPR could provide a measure of diagnostic value of PDD or NBI over WLC. When we excluded studies with high RoBs, it showed that NBI had a higher sensitivity (95.85%, IQR 88.80-99.60%) and FPR (25.01%, IQR 19.02-28.34%) than HAL or 5-ALA at lesion-level ... ................
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