Laboratory Reference Values - BGU

The new england journal of medicine

case records of the massachusetts general hospital

Founded by Richard C. Cabot Nancy Lee Harris, m.d., Editor Jo-Anne O. Shepard, m.d., Associate Editor Sally H. Ebeling, Assistant Editor

Stacey M. Ellender, Assistant Editor Christine C. Peters, Assistant Editor

Laboratory Reference Values

Alexander Kratz, M.D., Ph.D., M.P.H., Maryjane Ferraro, Ph.D., M.P.H., Patrick M. Sluss, Ph.D., and Kent B. Lewandrowski, M.D.

From the Department of Pathology Clinical Hematology Laboratory (A.K.), Microbiology Laboratory (M.F.), and Immunodiagnostics Laboratory (P.M.S.) and the Department of Pathology (K.B.L.), Massachusetts General Hospital; and Harvard Medical School (A.K., M.F., P.M.S., K.B.L.).

N Engl J Med 2004;351:1548-63.

Copyright ? 2004 Massachusetts Medical Society.

The following is a table of reference values for adults for laboratory tests commonly ordered at the Massachusetts General Hospital (MGH) and recorded in the Case Records. The table revises the most recently published data (Normal Reference Laboratory Values. N Engl J Med 1998;339:1063-72). Laboratory values are expressed in the units used at the MGH and the units of the Syst?me International d'Unit?s (SI units). The table is not intended to provide a comprehensive review of reference values, since this information is widely available in standard textbooks. To avoid suggesting an endorsement of commercial products by the hospital or the Journal, information on specific methods and instruments is not provided. Reference values are affected by many variables, including the patient population and the laboratory methods used. The ranges used at the MGH may therefore not be appropriate for other institutions and may not be optimal in some situations.

1548

n engl j med 351;15 october 7, 2004

Downloaded from by A MARK B. CLARFIELD on October 7, 2005 . Copyright ? 2004 Massachusetts Medical Society. All rights reserved.

case records of the massachusetts general hospital

Hematology and Coagulation.

Analyte

Specimen*

Activated clotting time

WB

Activated protein C resistance (factor V Leiden)

P

Alpha 2 -antiplasmin

P

Antiphospholipid-antibody panel

Partial-thromboplastin time?lupus anticoagulant screen P

Platelet-neutralization procedure

P

Dilute viper-venom screen

P

Anticardiolipin antibody

S

IgG

IgM

Antithrombin III

P

Antigenic

Functional

Anti-Xa assay (heparin assay)

P

Unfractionated heparin

Low-molecular-weight heparin

Danaparoid

Bleeding time

Carboxyhemoglobin

WB

Nonsmoker

Smoker

Clot retraction

WB

Cryofibrinogen

P

d-Dimer

P

Differential blood count

WB

Neutrophils

Band forms

Lymphocytes

Monocytes

Eosinophils

Basophils

Erythrocyte count

WB

Male

Female

Erythrocyte lifespan

WB

Normal survival

Chromium labeled, half-life

Erythrocyte sedimentation rate

WB

Female

Male

Factor II, prothrombin

P

Factor V

P

Factor VII

P

Factor VIII

P

Factor IX

P

Units Used at MGH 70?180 sec Ratio >2.1 80?130%

Negative Negative Negative

0?15 GPL units 0?15 MPL units

22?39 mg/dl 80?130%

0.3?0.7 IU/ml 0.5?1.0 IU/ml 0.5?0.8 IU/ml 2.0?9.5 min

0?2.3% 2.1?4.2% 50?100%/2 hr Negative ................
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