M.Sc Life Sciences Animals and Plants.docx



Central University of Punjab, BathindaPh.D. Program in Biochemistry Session-2020Department of BiochemistryProgram OutcomeThe learners of this programme will be able to:have research aptitude and desired skills to undertake challenging and new opportunities in academia and industry with reference to translational fields. Solve problems in health, agriculture and environment related to biochemistry. Generate new knowledge in basic as well as applied biochemistry leading to translational output for societal welfare.Course Structure of the ProgramCourse CodeCourse TitleLPCrLBC.701Research Methodology and Computer Applications40?4LBC.702Advanced Biochemistry40?4 XXXAny other Life Sciences PhD Course40?4LBC.751Research and Publication Ethics20?2Total Credits14 L: Lectures; P: Practical; Cr: CreditsIn addition to the course work, 80 research credits are required for the award of PhD degree. Details of syllabusLTPCr4004Course Code: LBC.701Course Title: Research Methodology and Computer Applications Total Hours: 60 Learning outcome is to:Demonstrate general principles of research, technical writing, good lab practice, research ethics and bioinformatics.Apply and effectively communicate scientific reasoning and data analysis in both written and oral forums related to research methodology and computer applications in research.Describe and correlate various principles of research and ethics.Unit I 20 HoursGeneral Principles of Research: Meaning and importance of research, Critical thinking, Formulating hypothesis and development of research plan, Review of literature, Interpretation of results and discussion. Bibliographic index and?research?quality parameters: citation index, impact factor,?h?index, i10 index, etc.?Research?engines such as google scholar, Scopus, web of science, etc. Technical Writing: Scientific writing, Writing synopsis, Research paper, Poster preparation, oral presentations and Dissertations. Reference Management using various softwares such as Endnote, reference manager, Refworks, etc. Communication skills: defining communication; type of communication; techniques of communication, etc. Library:?Classification systems, e-Library, Reference management, Web-based literature search engines.Unit II 20 HoursIntroduction and Principles of Good Lab Practices: Good laboratory practices, Biosafety for human health and environment. Biosafety issues for using cloned genes in medicine, agriculture, industry, and eco-protection, Biological containment and physical containment, CDC Biosafety levels, Biosafety in Clinical laboratories and biohazard management, Physical, Chemical & Biological hazards.Research Ethics: Ethical theories, Ethical considerations during research, data manipulations, subject consent, Animal testing. Animal rights, Perspectives and methodology & Ethical issues of the human genome project. Intellectual property protection (IPP) and intellectual property rights (IPR), WTO (World Trade Organization), WIPO (World Intellectual Property Organization), GATT (General Agreement on Tariff and Trade), TRIPs (Trade Related Intellectual Property Rights), TRIMS (Trade Related Investment Measures) and GATS (General Agreement on Trades in Services). Patents, Technology Development/Transfer Commercialization Related Aspects, Ethics.Plagiarism:??Plagiarism, definition, Search engines, regulations, policies and documents/thesis/manuscripts checking through softwares, Knowing and Avoiding Plagiarism during documents/thesis/manuscripts/scientific writing.Unit III 10 HoursComputer Application Software: Spreadsheet applications, Word-processing applications, Presentation applications, Internet browsers, Reference Management, and Image processing applications. World wide web: Origin and concepts, Overview of internet and its application for quality literature collection and secondary data related to research work. Exploring various websites and search engines. Computer applications to statistical packages. In silico approaches for drug designing.Unit IV 10 HoursBioinformatics: Organization, management and analysis of biological data, use of computers in data analysis, biological databases - DNA sequence databases and protein sequence databases, BLAST, FASTA, multiple sequence alignment, primers in biology (design and types of primers) genome projects (human, Arabidopsis and other genome projects), NCBI, UCSC and other database searches.Suggested Readings:Gupta, S. (2008). Research Methodology and statistical techniques. Deep & Deep Publications (P) Limited, New Delhi.Kothari, C. R. (2014). Research methodology (s). New Age International (p) Limited. New Delhi.Sahay, Vinaya and Pradumna Singh (2009). Encyclopedia of Research Methodology in life sciences. Anmol Publications. New Delhi.Kauda J. (2012). Research Methodology: A Project Guide for University Students. Samfunds literature Publications.Dharmapalan B. (2012). Scientific Research Methodology. Narosa PublishingNorman, G. and Streiner, D. (2008). Biostatistics: The Bare Essentials.3/e (with SPSS). Decker Inc. USA.Rao, P. P., S. Sundar and Richard, J. (2009). Introduction to Biostatistics and Research Methods. PHI learning.Christensen, L. (2007). Experimental Methodology. Boston: Allyn & Bacon.Fleming, D. O. and Hunt, D.L. (2006). Biological Safety: Principles and Practices. American Society for Microbiology, USA.Rockman, H. B. (2004). Intellectual Property Law for Engineers and Scientists. Wiley-IEEE Press, USA.Shannon, T. A. (2009). An Introduction to Bioethics. Paulist Press, USA.Vaughn, L. (2009). Bioethics: Principles, Issues, and Cases. Oxford University Press, UK.LTPCr4004Course Code: LBC.702 Course Title: Advanced Biochemistry Total Hours: 60 Learning outcome is to:Demonstrate advanced biochemistry including metabolism and stress biology.Apply and effectively communicate scientific reasoning and data analysis in both written and oral forums related to advanced biochemistry.Describe and correlate various aspects of metabolism and related advanced techniques.Unit I 15 HoursMetabolism: Recent advances in amino acid, carbohydrate, lipid and nucleotide metabolism.Unit II 15 HoursXenobiotic Metabolism: Chemical nature of xenobiotic; Transport of xenobiotic within the body; Fate of metabolism; Biotransformation; Detoxification; Examples of xenobiotic metabolismUnit III 15 HoursStress Biology: The stress response; Biomarkers of chronic stress and their role in diagnosis and therapy; Metabolic and neuroendocrine biomarkers; Exocytosis and ER Stress: Role of disruptive function of glycosylation/inter- and intra-molecular disulfide bond formation.Unit IV 15 HoursAdvanced Techniques and Applications: Metabolomics, Proteomics, protein-protein interactions, protein-metabolite interactions; Applications in Agriculture and Human Health.Suggested Reading: Research papers and reviews published in peer-reviewed international journals in the above areas.LTPCr2002Course Code: LBC.751Course Title: Research and Publication Ethics Total Hours: 30Unit I Philosophy and Ethics 3 hoursIntroduction to Philosophy : definition, nature and scope, content, branchesEthics : definition, moral philosophy, nature of moral judgements and reactions Unit II Scientific Conduct 5 hoursEthics with respect to science and researchIntellectual honesty and research integrityScientific misconducts : Falsification, Fabrication, and Plagiarism (FFP)Redundant publications : duplicate and overlapping publications, salami slicingSelective reporting and misrepresentation of data Unit III: Publication ethics 7 hours Publication ethics : definition, introduction and importance Best practices/ standards setting initiatives and guidelines: COPE, WAME, etc.Conflicts of interestPublication misconduct : definition, concept, problems that lead to unethical behaviour and vice versa, typesViolation of publication ethics, authorship and contributor shipIdentification of publication misconduct, complaints and appealsPredatory publishers and journals Unit IV Open Access Publishing 4 hoursOpen access publications and initiatives SHERPA/RoMEO online resource to check publisher copyright & self-archiving policiesSoftware tool to identify predatory publication developed by SPPUJournal finder/journal suggestion tools viz. JANE, Elsevier Journal Finder, Springer Journal Suggester, etc.Unit V Publication Misconduct 4 hoursGroup Discussions: Subject specific ethical issues, FFP, authorship; conflicts of interest; complaints and appeals: examples and fraud from India and abroadSoftware tools: Use of plagiarism software like Turnitin Urkund and other open source software toolsUnit IV Databases and Research Metrics 7 hoursDatabases: Indexing databases; Citation database: Web of Science, Scopus etc. Research Metrics: Impact Factor of journal as per Journal Citation Report, SNIP, SJR, IPP, Cite Score; Metrics : h-index, g-index, i10 index, almetrics ................
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