Diphenhydramine (Benadryl) Dosage Table
Diphenhydramine (Benadryl) Dosage Table
This handout contains child doses of an over-the-counter medicine. Use these instructions only with
guidance from your child¡¯s primary healthcare provider who prescribed this medicine.
Generic name: Diphenhydramine
Common brand name: Benadryl
Age limit
Do not give diphenhydramine to children less than 6 years of age unless
your health care provider tells you to.*
There are other medicines similar to diphenhydramine that will not make
your child sleepy (like loratadine, cetirizine, fexofenadine). These can be
bought without a prescription and are safer for young children.
Dosage
This medicine comes in different strengths and forms including liquid,
capsules, chewable tablets and tablets you swallow. To give the proper dose
to your child, look at milligrams (mg) strength on the bottle¡¯s label. Use the
measuring device that comes with the bottle. Do not use your kitchen
measuring spoons or silverware.
How often
Repeat every 6 to 8 hours as needed for up to 48 hours (2 days) unless
directed to take longer by your child¡¯s healthcare provider.
How to use the table
To give the proper dose of diphenhydramine, you must know your child¡¯s
current weight.
Child's weight in Pounds
Abbreviated = lbs
20 to 24 lbs
25 to 37 lbs
Liquid 12.5 mg/5 mL
4 mL
use oral syringe
5 mL
7.5 mL
10 mL
Give adult
use dosing cup use dosing cup use dosing cup dose
Chewable 12.5 mg tablets
Do not use
1 tablet
1? tablets
2 tablets
4 tablets
Capsules or tablets 25 mg
Do not use
Do not use
Do not use
1 tablet
2 tablets
Kilograms = kgs
9 to 11 kgs
12 to 16 kgs
38 to 49 lbs
17 to 22 kgs
50 to 99 lbs
23 to 45 kgs
100+ lbs
46+ kgs
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To Learn More
? Ask your child¡¯s healthcare provider
?
Free Interpreter Services
? In the hospital, ask your nurse.
? From outside the hospital, call the
toll-free Family Interpreting Line,
1-866-583-1527. Tell the interpreter
the name or extension you need.
Diphenhydramine (Benadryl) Dosage Table
Notes of Caution
? Consult healthcare provider if your child has underlying medical problems
(especially seizures, thyroid or urinary tract conditions). Consult
healthcare provider if your child has had adverse reactions to this or any
antihistamine medicines in the past.
? Adverse reactions are not common but can include excitability,
restlessness, dizziness.
? Side effects could be drowsiness, sedation, dry mouth. Use lowest dose to
minimize drowsiness.
? Keep this and all medicine out of reach of children. Call the Washington
Poison Center at 1-800-222-1222 if you suspect your child has overdosed
on a medicine.
Approved by Seattle Children¡¯s Pharmacy & Therapeutics Committee
5/16/2023
*Dosing recommendations align with FDA OTC labeling and AAP
Seattle Children¡¯s offers free interpreter services for patients, family members and legal representatives who are deaf or hard of
hearing or speak a language other than English. Seattle Children¡¯s will make this information available in alternate formats upon
request. Call the Family Resource Center at 206-987-2201. This handout has been reviewed by clinical staff at Seattle Children¡¯s.
However, your needs are unique. Before you act or rely upon this information, please talk with your healthcare provider.
5/23
PE1304
? 2023 Seattle Children¡¯s, Seattle, Washington. All rights reserved.
Patient and Family Education
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