Pharmacology: Basics for RNs

Apr 16, 2016 · Clearance - The clearance of a drug (CL) is the theoretical volume of plasma from which the drug is entirely removed in a unit of time. It is calculated as: CL = Rate of Elimination (ROE) / C (concentration) For example, if a drug is 20 mcg/mL and the ROE is 100 mcg/min, the clearance will be: CL = 100mcg/min / 20mcg/mL = 5 mL/min ................
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