DRAFT Toluene HEAC Assessment and PEL Recommendation …
The median reduction in tumour volume was 20.6% in study B2402 at 24 weeks (n=46) and 29.9% at 48 weeks (n=29) and 24.5% in study B2401 at 24 weeks (n=91) and 36.2% at 48 weeks (n=84). The percentage change in tumour volume during the course of the investigation was assessed by MRI for the intent-to-treat population. ................
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