PDF Celebrating 200 Years at the Forefront of Medicine

Celebrating 200 Years at the Forefront of Medicine

a special collection of review and perspective articles published in 2012 to commemorate the nejm 200th a nniversary.

Celebrating 200 Years at the Forefront of Medicine

A special collection of review and perspective articles published in 2012 to commemorate the nejm 200th anniversary

Selections from the new england journal of medicine

Copyright ? 2013 Massachusetts Medical Society. All rights reserved. Printed in the United States of America.

Except as permitted under the United States Copyright Act of 1976, no part of this work may be reproduced, displayed, transmitted, or distributed in any form or by any means or stored in a data base or retrieval system, without prior written permission of the publisher from the Rights and Permissions Department, Massachusetts Medical Society, 860 Winter Street, Waltham, MA 02451. This book is provided for informational purposes only, to complement other sources.

dear colleague:

In 2012, the New England Journal of Medicine celebrated 200 years of publishing practice-changing medical advances. Throughout the anniversary year, we published special content to commemorate this landmark event. The content that was published in print, a series of Review and Perspective articles that each explore a story of progress, is now collected in this book.

We hope that this collection continues to provide value and interest. The 200th anniversary celebrated the NEJM community -- from researcher to clinician reader -- that works together to bring discovery to practice every day. Thank you to all of those who contribute to this mission.

Jeffrey M. Drazen, M.D. Editor-in-Chief The New England Journal of Medicine

celebrating 200 years ii

the new england journal of medicine

contents

1 NEJM@200 -- Two Centuries at the Journal

3 A Reader's Guide to 200 Years of the New England Journal of Medicine Allan M. Brandt, Ph.D.

10 A Tale of Coronary Artery Disease and Myocardial Infarction Elizabeth G. Nabel, M.D., and Eugene Braunwald, M.D.

20 The Perpetual Challenge of Infectious Diseases Anthony S. Fauci, M.D., and David M. Morens, M.D.

29 Patients and Doctors -- The Evolution of a Relationship Robert D. Truog, M.D.

35 A Patient with Asthma Seeks Medical Advice in 1828, 1928, and 2012 Erika von Mutius, M.D., and Jeffrey M. Drazen, M.D.

43 Major Trends in the U.S. Health Economy since 1950 Victor R. Fuchs, Ph.D.

48 What We Don't See Margaret Kendrick Hostetter, M.D.

55 The Evolving Roles of the Medical Journal Scott H. Podolsky, M.D., Jeremy A. Greene, M.D., Ph.D., and David S. Jones, M.D., Ph.D.

60 Two Hundred Years of Surgery Atul Gawande, M.D., M.P.H.

69 The Evolving Primary Care Physician Susan Okie, M.D.

75 Two Hundred Years of Cancer Research Vincent T. DeVita, Jr., M.D., and Steven A. Rosenberg, M.D., Ph.D.

83 The Burden of Disease and the Changing Task of Medicine David S. Jones, M.D., Ph.D., Scott H. Podolsky, M.D., and Jeremy A. Greene, M.D., Ph.D.

89 Two Centuries of Assessing Drug Risks Jerry Avorn, M.D.

95 Doctors, Patients, and Lawyers -- Two Centuries of Health Law George J. Annas, J.D., M.P.H.

101 Unfinished Journey -- A Century of Health Care Reform in the United States Jonathan Oberlander, Ph.D.

107 Tuberculosis, Drug Resistance, and the History of Modern Medicine Salmaan Keshavjee, M.D., Ph.D., and Paul E. Farmer, M.D., Ph.D.

113 Therapeutic Evolution and the Challenge of Rational Medicine Jeremy A. Greene, M.D., Ph.D., David S. Jones, M.D., Ph.D., and Scott H. Podolsky, M.D.

119 The Past 200 Years in Diabetes Kenneth S. Polonsky, M.D.

128 Two Hundred Years of Progress in the Practice of Midwifery Michael F. Greene, M.D.

137 A Glimpse of the Next 100 Years in Medicine Isaac S. Kohane, M.D., Ph.D., Jeffrey M. Drazen, M.D., and Edward W. Campion, M.D.

139 200th Anniversary Special Edition Poster Illustrations

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