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SDF should not be administered to Rh negative or splenectomized patients as efficacy has not been demonstrated. Only 10% to 15% of the population is Rh negative. Rh status can be established by a simple blood test prior to therapy. An intravenous dose of 125 to 250 IU/kg (25 to 50 µg/kg) body weight is recommended for individuals with ITP ... ................
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