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Unlike the Henschke study above, 66% of 1,520 patients age > 50 and tobacco use > 20 pack-years had one or more non-calcified nodules. One year after enrollment, 1.7% of enrolled patients were diagnosed with lung cancer (1.1% of all nodules were malignant) and 0.9% of participants were diagnosed with stage IA NSCLC. ................
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