Homepage - Kentucky Department of Education

A morphine-equivalent dose (MED) ≥20 mg per day. Switching to another opioid. Chronic pulmonary disease. Sleep apnea. Asthma. Chronic kidney and/or liver impairment. Use of CNS depressants, including benzodiazepines and alcohol. Use of certain medications for depression, including monoamine oxidase inhibitors (MAOIs) SIGNS AND SYMPTOMS OF ... ................
................