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Supplemental Digital Content 2. Most Common Signs and Symptoms of Head, Neck, and Oral Cancer Painless white or red patch in mouthHoarseness or change in voiceSore throat or mouth sore (does not heal)Painless lump in the mouth or neckDifficulty chewing, swallowing, or breathingFrequent nose bleed (particularly on one side)Hearing loss or ear pain, particularly in one) Blood in saliva or phlegmWeight lossFatigueHead and Neck Cancer Alliance, 2012. ................
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