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Acute pain is a hallmark of SCD. Many patients experience pain daily, but several studies have documented the undertreatment of sickle cell pain. The three classes of drugs used to treat SCD pain include NSAIDs, opioids (e.g., codeine, hydrocodone, morphine, oxycodone), and selective serotonin reuptake inhibitors (SSRIs; e.g. paroxetine ... ................
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