Events.cancer.gov
The PD-1/PD-L1 pathway is crucial for the development of immune tolerance, a process of negative selection of auto-reactive lymphocytes taking place in primary (central tolerance) and secondary lymphoid organs (peripheral tolerance).29 High PD-L1 expression is in fact demonstrated within the thymus and on dendritic cells, where the PD-L1/PD-1 ... ................
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