Events.cancer.gov
The PD-1/PD-L1 pathway plays a critical role in tumor evasion and is an attractive target for therapeutic intervention in HL. High frequency of expression of PD-L1 by immunohistochemistry and flow cytometry has been demonstrated in cHL. A recent integrated analysis reveals selective 9p24.1 amplification, which includes the PD-L1 and PD-L2 loci, increased PD-L1 and PD-L2 expression, and further ... ................
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