UNIVERSITY OF PENNSYLVANIA PERELMAN SCHOOL OF …

[Pages:22]UNIVERSITY OF PENNSYLVANIA PERELMAN SCHOOL OF MEDICINE CURRICULUM VITAE

Date: March 15, 2016

JEFFREY HOWARD SILBER, M.D., Ph.D.

Office Address:

The Children's Hospital of Philadelphia Center for Outcomes Research 3535 Market Street, Suite 1029 Philadelphia, PA 19104 Tel.: (215) 590-5635 Fax: (215) 590-2378 email: silber@email.chop.edu

Education:

1972-1976 1976-1980 1985-1990

1997

A.B. (summa) Washington University, Department of Economics,

St. Louis, Missouri

M.D.

Johns Hopkins Medical School, Baltimore, Maryland

Ph.D.

The University of Pennsylvania (Department of Health Care

Systems, The Graduate Group in Managerial Science and

Applied Economics), Philadelphia, PA

M.A.

Honorary Masters Degree, Philosophy, The University of

Pennsylvania, Philadelphia, PA

Postgraduate Training and Fellowship Appointments: 1980-1981 Intern in Pediatrics, Johns Hopkins Hospital, Baltimore, MD 1981-1982 Junior Resident in Pediatrics, Johns Hopkins Hospital, Baltimore, MD 1982-1983 Senior Resident in Pediatrics, Johns Hopkins Hospital, Baltimore, MD 1983-1985 Robert Wood Johnson Foundation Clinical Scholar, The University of Pennsylvania School of Medicine, Philadelphia, PA 1985-1988 Fellow, Pediatric Hematology-Oncology, The Children's Hospital of Philadelphia, Philadelphia, PA

Faculty Appointments: 1985-present 1988-1989 1989-1997 1992-present 1996-1997 1997-2004 1997-2004 1997-2004 2004-present

Senior Fellow, Leonard Davis Institute of Health Economics, The Wharton School, The University of Pennsylvania Instructor, Division of Pediatric Oncology, The Department of Pediatrics, The University of Pennsylvania School of Medicine Assistant Professor of Pediatrics, The University of Pennsylvania School of Medicine Associate Scholar, Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania Assistant Professor of Anesthesiology and Critical Care, The University of Pennsylvania School of Medicine Associate Professor of Anesthesiology and Critical Care, The University of Pennsylvania School of Medicine Associate Professor of Pediatrics, The University of Pennsylvania School of Medicine Associate Professor of Health Care Systems, The Wharton School, The University of Pennsylvania Professor of Pediatrics, The University of Pennsylvania School of Medicine

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2004-present 2004-present

Professor of Health Care Management (formerly Health Care Systems), The Wharton School, The University of Pennsylvania Professor of Anesthesiology and Critical Care, The University of Pennsylvania School of Medicine

Hospital and Administrative Appointments: 1989-present Attending, Pediatric Oncology Long Term Follow-Up Clinic, Division of Oncology, The Children's Hospital of Philadelphia 1993-2008 Faculty Member, Division of Biostatistics and Epidemiology, Department of Pediatrics, The University of Pennsylvania School of Medicine 1997-present Director, Center for Outcomes Research, The Children's Hospital of Philadelphia 2013-present Nancy Abramson Wolfson Professor of Health Services Research, The Children's Hospital of Philadelphia

Specialty Certification: 1985 1987

Board Certified, American Board of Pediatrics Board Certified, Pediatric Hematology and Oncology (subspecialty), American Board of Pediatrics

Licensure:

1983

Pennsylvania: MD 028141-E

Awards, Honors and Memberships in Honorary Societies:

1976

A.B. summa cum laude; John M. Olin Prize in Economics; Phi Beta

Kappa: Washington University

1978

Henry Strong Denison Research Award: Johns Hopkins Medical School

1986 & 1988 National Research Service Award

1988

The Health Services Improvement Fund, Inc. Doctoral Student Award

1989

National Institute of Health Research Career Development Award

1995

John Morgan Society

1996

National Institute of Health Insurers of America Finalist (top 3 papers)

1997

Ethel Brown Foerderer Fund for Excellence Award

2000

Samuel P. Martin Health Services Research Award

2003

AcademyHealth Article-of-the-Year Award

2003

The Hummeler Research Prize (Article-of-the-Year), Joseph Stokes, Jr.

Research Institute

2007

AcademyHealth Abstract-of-the-Year Award

2011

AcademyHealth Article-of-the-Year Award

2013-present Nancy Abramson Wolfson Professor of Health Services Research, The

Children's Hospital of Philadelphia

2015-present Fellow, The College of Physicians of Philadelphia

Memberships in Professional and Scientific Societies: National Societies: AcademyHealth American Economics Association American Federation for Medical Research American Medical Association American Society of Clinical Oncology International Biometric Society International Health Economic Association Society for Medical Decision Making Society for Clinical Trials Society for Pediatric Research

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Local Societies:

John Morgan Society (President, 2014-present; Treasurer, 2012-2014)

National Committees:

1992

Long-Term Follow Up (Late Effects), Children's Cancer Group (CCG)

1992

CCG Third-Party Payment Committee

1993

CCG Lymphoma Committee

1994

CCG Long Term Follow-up Committee

1995-1999 Committee on Health Services Research of the American Society of

Clinical Oncology (ASCO)

1996-1997 Committee on Guidelines for Use of Antiemetics (ASCO)

1998-2003 Oncology Measurement Advisory Panel of the National Committee for

Quality Assurance (NCQA)

2004-2008 Children's Asthma Care Core Measure Advisory Panel of the Joint

Commission on Accreditation of Healthcare Organizations (JCAHO)

2008-present Technical Expert Panel, Measures Support Work for Centers for Medicare

and Medicaid (CMS): Measuring Complications of Inpatient Care

2009-2010 Association of American Medical Colleges, Working Group for

Developing Process Measures

2011-present Chair, Pediatric Quality Measurement Program Working Group on Racial

Disparities (Agency for Healthcare Research and Quality)

2014-present Linking Cost and Quality Measures Expert Panel (National Quality

Forum)

Reviewer:

Anesthesiology Annals Internal Medicine Health Services Research Journal of the American Medical Association Journal of Clinical Oncology Journal of General Internal Medicine Medical Care New England Journal of Medicine Pediatrics

Editorial/Peer Review Positions:

1993

Special Reviewer, American Academy of Pediatrics in collaboration with

the Agency for Health Care Policy and Research. In: Clinical Practice and

Guidelines for Management of Otitis Media with Effusion in Children

1993

Special Reviewer, AHCPR, Technology Assessment Study Section

1994

Special Reviewer, British Columbia Health Research Foundation, 3/94

1996

Panelist, National Cancer Institute/American Society of Clinical Oncology

Economics Workshop "Economic Analysis in Clinical Trials,"

Washington, DC, 5/13-14/96 (To draft policy regarding the use of cost

benefit and effectiveness analysis in cancer clinical trials.)

1996

Panelist, National Cancer Institute "Unresolved Issues in Cancer

Survivorship, Economics Workgroup," Bethesda, MD, 11/4/96

1997

Agency for Health Care Policy Research: Study Section on Small Grants,

Rockville, MD, 8/13/97

2002

Reviewer, Special Emphasis Panel of the National Center for

Complementary and Alternative Medicine

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2004

2009

2011 2012

Reviewer, Behavioral and Social Science of Aging Review Committee, National Institute of Aging Reviewer, Robert Wood Johnson Foundation Interdisciplinary Nursing Quality Research Initiative Program Advisor, Medicare Payment Advisory Commission Panel, 11/18/11 Advisor, The Joint Commission's Development of Risk-Adjusted Outcome Measures in the Electronic Health Record Environment Invitational Conference, 3/13-14/12

Academic Committees at The Children's Hospital of Philadelphia: 1990-1991 Fellowship Committee 1991-1993 Departmental Computer Committee 1994-1995 General Clinical Research Center Committee 1996-1998 Pediatric Fellowship Committee 2008-2010 Search Committee, Division of Epidemiology and Biostatistics

Academic Committees at the University of Pennsylvania:

1992, 1993 Subcommittee on Health Care Organization, Law, and Financing Task

Force on Social, Preventive, and Community Medicine

1993

Chair, Committee on Technology Adoption and Global Budgets, The

Leonard Davis Institute of Health Economics

1997-1999 Greenwall Project, Center for Bioethics

1998-present Executive Committee, Leonard Davis Institute of Health Economics, The

Wharton School, The University of Pennsylvania

2001-2003 Research Committee, The University of Pennsylvania

2002-2004 Search Committee, Department of Anesthesia Chair

2005-2007 University Research Foundation Biomedical Committee

2005-present Center for Clinical Epidemiology and Biostatistics Admissions Committee

2008-2009 Search Committee, General Internal Medicine

Major Teaching Responsibilities at the University of Pennsylvania School of Medicine:

1993

Epidemiology Course for Medical Students, ME254

1994

Proseminar in Health Services Research, HCM 900

1997-present Center for Clinical Epidemiology and Biostatistics: Outcomes Research,

EPI 580 (fall semester)

1997-present Health Care Quality: Measurement and Management,

HCMG 212 (spring semester)

Lectures by Invitation (past 5 years): May 13, 2011

The President's Lecture: Large administrative database research: Medicare and beyond. Association of University Anesthesiologists Annual Meeting, Philadelphia, PA

June 12, 2011

Article of the Year Award Lecture: Aggressive treatment style and surgical outcomes. AcademyHealth Annual Meeting, Seattle, WA

October 17, 2011

Measuring quality of care in surgery and anesthesia. Foundation for Anesthesia Education and Research Invited Panel on Outcomes Research. American Society of Anesthesiologists Annual Meeting, Chicago, IL

November 1, 2011

Describing and understanding healthcare disparities in operative procedure length. American Public Health Association Annual Meeting, Washington, DC

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November 15, 2011 Do you get what you pay for ? Quality in healthcare? Critical Care Canada Forum, Toronto, Canada

November 18, 2011 Mistaken advice on AMI by Hospital Compare. Medicare Payment Advisory Commission Panel, Washington, DC

December 6, 2011

Examining perioperative care using multivariate matching. Division of Clinical and Translational Research Seminar Lecture, Department of Anesthesiology, Washington University, St. Louis, MO.

December 7, 2011

Public reporting of healthcare quality: Misleading advice from Medicare's Hospital Compare. Grand Rounds, Department of Anesthesiology, Washington University, St. Louis, MO

April 2, 2012

Challenges implementing a hierarchical model for use in public reporting: The case of Hospital Compare. Eastern North American Region (ENAR) of the International Biometric Society Annual Meeting, Washington, DC

May 1, 2012

Challenges in estimating continuous enrollment in Medicaid and CHIP. Pediatric Academic Societies Annual Meeting, Boston, MA

May 9, 2012

Using multivariate matching to identify and understand disparities. Pediatric Quality Measurement Program Working Group on Racial Disparities, AHRQ Webconference, Philadelphia, PA

May 30, 2012

The pediatric quality measurement project. Grand Rounds, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA

June 2, 2012

Racial disparities in breast cancer survival. American Society of Clinical Oncology Annual Meeting, Chicago, IL

June 14, 2012

Using multivariate matching to study racial disparities. 2nd Annual CMS Medicaid/CHIP Quality Conference: Improving Care and Proving It!, Baltimore, MD

June 23, 2012

Challenges in estimating continuous enrollment in Medicaid and CHIP. AcademyHealth Annual Meeting, Orlando, FL

October 16, 2012

Studies of cancer survival using multivariate matching: Examining treatment questions in ovarian and breast cancer. Grand Rounds, Department of Medicine, Jersey Shore University Medical Center, Neptune, NJ

January 7, 2014

Understanding racial disparities in breast and colon cancer survival using tapered multivariate matching. Center for Childhood Cancer Research Hematology/Oncology Seminar Series, The Children's Hospital of Philadelphia, Philadelphia, PA

January 10, 2014

Template matching for auditing hospital quality and cost. Center for Pediatric Clinical Effectiveness Research Faculty Seminar Series, The Children's Hospital of Philadelphia, Philadelphia, PA

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February 17, 2014

Misleading advice on AMI mortality from Hospital Compare. Pediatric Cardiology Research Lecture, The Children's Hospital of Philadelphia, Philadelphia, PA

April 29, 2014

Misleading advice on heart attack mortality: How Medicare's Hospital Compare misleads the public. The John Morgan Society, The University of Pennsylvania, Philadelphia, PA

September 8, 2014 Template matching to compare hospital resource utilization. The Children's Hospital Association, Washington, DC

September 23, 2014

Template matching to compare hospital resource utilization and quality of care. Department of Pediatrics, Quality and Patient Safety Champions Meeting, The Children's Hospital of Philadelphia, Philadelphia, PA

November 11, 2014 Misleading advice on heart attack mortality from Medicare's Hospital Compare random effects model. Department of Statistics and Operations Research, Tel Aviv University, Tel Aviv, Israel

February 13, 2015

Assessing hospital cost, quality, and comparative advantage using multivariate matching. Public Health Economics Seminar. Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

February 19, 2015

Comparing children's hospitals on resource utilization in asthma and complex chronic disease. PolicyLab, The Children's Hospital of Philadelphia, Philadelphia, PA

February 23, 2015

Matching methods to audit hospital cost, quality, and value. Center for Medicare & Medicaid Innovation and Centers for Medicare & Medicaid Services, Baltimore, MD

March 12, 2015

Using matching methods to compare hospital cost and quality. Pediatric Health Information System (PHIS) Spring Meeting, San Francisco, CA

March 30, 2015

Using multivariate matching to study racial disparities and hospital quality of care. Comprehensive Cancer Center Research Seminar, University of Alabama, Birmingham, AL

May 6, 2015

Template matching of children with complex chronic conditions hospitalized for surgical procedures. Defense Health Agency, Falls Church, VA

May 14, 2015

Using multivariate matching to compare hospital quality of care. Association of American Medical Colleges (AAMC), Washington, DC

May 28, 2015

Using matching methods to compare hospital cost and quality in PHIS. Pediatric Health Information System (PHIS), Webinar, Philadelphia, PA

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June 13, 2015

Comparing hospitals on resource use in medical admissions of children with complex chronic conditions. AcademyHealth Annual Meeting, Minneapolis, MN

June 13, 2015

New approaches for measuring quality, cost and value: Applications for studying nursing care. Keynote Speaker, Interdisciplinary Research Group on Nursing Issues (IRGNI) Meeting, AcademyHealth Annual Meeting, Minneapolis, MN

June 13, 2015

Template matching, hospital specific template matching and indirect standardization matching. The Anesthesiology and Surgery Interest Group, AcademyHealth Annual Meeting, Minneapolis, MN

June 14, 2015

New tools for studying racial disparities and hospital quality of care: Tapered matching, template matching and indirect standardization matching. AcademyHealth Annual Meeting, Minneapolis, MN

June 15, 2015

Practice style variation in pediatric inpatient asthma care. AcademyHealth Annual Meeting, Minneapolis, MN

June 15, 2015

Template matching of children with complex chronic conditions hospitalized for surgical procedures. AcademyHealth Annual Meeting, Minneapolis, MN

September 10, 2015 New methods for comparing hospital quality, cost and value. Ophthalmology Grand Rounds, Scheie Eye Institute, Philadelphia, PA

October 4, 2015

Improving Medicare's Hospital Compare Mortality Model. AHRQ Research Conference ? Producing Evidence and Engaging Partners to Improve Health Care, Arlington, VA

October 9, 2015

Enhancing the Hospital Compare mortality model using a Bayesian framework. International Conference on Health Policy Statistics, Providence, RI

November 17, 2015 Indirect standardization matching. Center for Childhood Cancer Research Seminar Series, The Children's Hospital of Philadelphia, Philadelphia, PA

January 13, 2016

Multivariate matching to assess hospital cost, quality, and value. Grand Rounds, Children's National Health System, Washington, DC

March 11, 2016

Auditing resource utilization in Medicaid and Non-Medicaid hospitalizations. Pediatric Health Information System (PHIS) Spring Meeting, New Orleans, LA

Bibliography: Research Publications, Peer Reviewed: 1. Silber JH, Kaizer H. Loss weighting and the human cost of experimentation. J Chron Dis 1985; 38:507-516. PMID: 4008591.

2. Meadows AT, Silber JH. Delayed consequences of therapy for childhood cancer. CA Cancer J Clin 1985; 35:271-286. PMID: 3930013.

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3. Peyster RG, Ginsberg F, Silber JH, Adler LP. Exophthalmos caused by excessive fat. CT volumetric analysis and differential diagnosis. Am J Radiol 1986; 146:459-464. PMID: 3484861.

4. Silber JH. Forecasting asthmatic wheezing using temperature velocity. Pediatr Emerg Care 1987; 3:13-17. PMID: 3562305.

5. Silber JH, Kaizer H. Marginal analysis applied to the dose-response curve. Med Pediatr Oncol 1988; 16:344-348. PMID: 3185363.

6. Silber JH, Littman PS, Meadows AT. Stature loss following skeletal irradiation for childhood cancer. J Clin Oncol 1990; 8:304-312. PMID: 2299373.

7. Silber JH, Evans AE, Fridman M. Models to predict outcome from childhood neuroblastoma: The role of serum ferritin and tumor histology. Cancer Res 1991; 51:1426-1433. PMID: 1997181.

8. Cohen AR, Martin MB, Silber JH, Kim HC, Ohene-Frempong K, Schwartz E. A modified transfusion program for prevention of stroke in sickle cell disease. Blood 1992; 79:1657-1661. PMID: 1558963.

9. Silber JH, Williams SV, Krakauer H, Schwartz JS: Hospital and patient characteristics associated with death after surgery. A study of adverse occurrence and failure to rescue. Med Care 1992; 30:615-629. PMID: 1614231.

10. Larsen R, Jakacki R, Vetter V, Silber JH, Barber G. Electrocardiographic changes and arrhythmias after cancer therapy in children and young adults. Am J Cardiol 1992; 70:73-77. PMID: 1615874.

11. Silber JH, Radcliffe J, Peckham V, Perilongo G, Kishnani P, Fridman M, Goldwein JW, Meadows AT. Whole brain irradiation and decline in intelligence: The influence of dose and age on IQ-score. J Clin Oncol 1992; 10:1390-1396. PMID: 1517781.

12. Wasserman R, Galili N, Ito Y, Silber JH, Reichard BA, Shane S, Womer RB, Lange B, Rovera G. Residual disease at the end of induction therapy as a predictor of relapse during therapy in childhood B-lineage acute lymphoblastic leukemia. J Clin Oncol 1992; 10:1879-1888. PMID: 1453203.

13. Jakacki RI, Goldwein JW, Larsen RL, Barber G, Silber JH. Cardiac dysfunction following spinal irradiation during childhood. J Clin Oncol 1993; 11:1033-1038. PMID: 8501489.

14. Rackoff WR, Kunkel N, Silber JH, Asakura T, Ohene-Frempong K. Pulse oximetry and factors associated with hemoglobin oxygen desaturation in children with sickle cell disease. Blood 1993; 81:3422-3427. PMID: 7685205.

15. Silber JH, Jakacki RI, Larsen RL, Goldwein JW, Barber G. Increased risk of cardiac dysfunction after anthracyclines in girls. Med Pediatr Oncol 1993; 21:477-479. PMID: 8341214.

16. Legorreta AP, Silber JH, Constantino GN, Kobylinski RW, Zatz SL. Increased cholecystectomy rate after the introduction of laparoscopic cholecystectomy. JAMA 1993; 270:1429-1432. PMID: 8371441.

17. Jakacki RI, Larsen RL, Barber G, Heyman S, Fridman M, Silber JH. Comparison of cardiac function tests after anthracycline therapy in childhood: Implications for screening. Cancer 1993; 72:27392745. PMID: 8402498.

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