NSAIDS

( CO2 production and O2 consumption. CV effects due to anemia only. GI effects: as mentioned before. Respiratory alkalosis later compensated by renal bicarb excretion. Later stages: pH falls, bicarb still low and CO2 is low or normal (I.e. uncompensated metabolic acidosis) Deranged carbohydrate metabolism accumulates pyruvic, lactic and ... ................
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