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-hydrolyzed to an acid and excreted in urine. Normeperidine E ½ x = 15 hrs *Seizure Activity* E ½ x of Meperidine = 3-5 hrs. 60% Protein Bound. Use Cautiously in Elderly and Renal Disease. Extensively Metabolized by: N-demethylation. Inactive metabolite = norfentanyl. Excreted by kidneys. Detected in urine 72 hrs after single dose. Rapidly ... ................
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