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APPENDIX: STUDY INVESTIGATORSPhase 2b Study Investigators ( Identifier: NCT00168701)Phase 3 DEFINE Study Investigators ( Identifier: NCT00420212) – parent of the ENDORSE extension studyPhase 3 CONFIRM Study Investigators ( Identifier: NCT00451451) – parent of the ENDORSE extension studyPhase 2b ( Identifier: NCT00168701)COORDINATING INVESTIGATOR: Ludwig Kappos, Universit?tsspital Basel, Basel, SwitzerlandCO-INVESTIGATORSCzech RepublicZdeněk Ambler, Hospital Pilsen, Department of Neurology, Pilsen; Edvard Ehler, Oddeleni Neurologie, Krajska Nemocnice Parbudice, Kyjevská, Pardubice; Eva Havrdova, Vseobecni Fakultni Nemocnice Neurologicke Oddeleni, Prague; Eva Meluzinova, Fakultni nemocnice v Motole Neurologicka Klinika. Prague; Ivan Rektor, Fakultni Nemocnice U sv. Anny v Brne, Neurologicka Klinika, Brno; Radomir Talab, Faculty Hospital, Neurological Clinic, Hradec KraloveGermanyRalf Gold, Neurologische Poliklinik, Universit?tsklinikum G?ttingen, G?ttingen; Hans-Peter Hartung, Heinrich-Heine-Universitat, DusseldorfHungaryAttila Csanyi, Petz Aladár County Hospital, Department of Neurology, Vasvári Palu; László Csiba, University of Debrecen, Department of Neurology, Nagyerdei; Gábor Jakab, Uzsoki Hospital, Department of Neurology, BudapestNetherlandsR.Q. Hintzen, Erasmus Medical Centre Department of Neurology, Rotterdam; Chris Polman, VUMC, Receptie J De Boelelaan, AmsterdamPolandWieslaw Drozdowski, Klinika Chorob Nerwowych, Akademii Medycznej w Bialymstoku, Samodzielny Publiczny Szpital Kliniczny, Bialystok; Waldemar Fryze, Wojewodzki Szpital Specjalistyczny, Kopernika Oddzial Neurologiczny i Leczenia Udarow Mozgu, Gdansk; Jan Kochanowicz, Niepubliczny Zaklad Opieki Zdrowotnej, Przychodnia Internistyczno-Stomatologiczna “KENDRON” Bialystok; Hubert Kwiecinski, Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Katedra i Klinika Neurologii, Warszaw; Zdzislaw Maciejek, Wojskowy Szpital Kliniczny z Poliklinik?, Samodzielny Publiczny Zak?ad Opieki Zdrowotnej, Klinika Neurologii Ul. Powstańców Warszawy, Bydgoszcz; Sebastian Schimrigk, Neurologische Klinik der Ruhr Universit?t Bochum am St. Josef-Hospital, Bochum; Krzysztof Selmaj, Uniwersytecki Szpital Kliniczny nr 1 im. N. Barlickiego w Lodzi, Oddzial Kliniczny Neurologii, Lodz; Andrzej Szczudlik, Centrum Neurologii Klinicznej Fundacja Przyszlosc Neurologii, Krakow; Andrzej Wajgt, Katedra i Klinika Neurologii Slaskiej Akademii Medycznej Samodzielny Publiczny Centralny Szpital Kliniczny, KatowiceRussiaAnna Belova, City Hospital No. 33, Research Institute of Traumatology and Orthopedics, Nizhniy. Novgorod; Aleksey N Boiko, Department of Neurology and Neurosurgery, Russian State Medical University, Moscow; Alexander Elchaninov, Central Medical Sanitary Department № 122, Neurology Department, St. Petersburg; Vladimir Kozlov, Institute of Clinical Immunology RAMS (Siberian branch), Clinic of Immunopathology, Novosibirsk; Miroslav M Odinak, Military Medical Academy S.M. Kirov MoD of Russian Federation, Neurology Clinic, St. Petersburg; Sergey B Shvarkov, Clinical Hospital № 83 of Federal Board MoH of Russian Federation, Moscow; Alexander Skoromets, Pavlov State Medical University of St-Petersburg, Neurology Department; St. Petersburg; Igor Stolyarov, Institute of the Human Brain, Department of Multiple Sclerosis, St-Petersburg; Olga Vorobieva, State Institution Central Military Hospital of Federal Security Service of Russian Federation, Moscow; Igor A Zavalishin, Scientific Research Neurology Institute RAMS, MoscowSwedenJan Hillert, Karolinska University hospital, Huddinge, Department of Neurology, Stockholm; Jan Lycke, MS Centrum, Forskningsenhet, Gothenburg; Tomas Olsson, Karolinska University Hospital, Department of Medicine, Neuroimmunology unit, Stockholm; Ludwig Kappos, Universit?tsspital Basel, Neurology-Neurosurgical Policlinic, BaselTurkeyMefkure Eraksoy, University of Istanbul, Istanbul Faculty of Medicine, Department of Neurology, Capa, Istanbul; Rana Karabudak, Hacettepe University Medical Facility, Department of Neurology, Ankara; Aksel Siva, University of Istanbul, Cerrahpasa School of Medicine, Department of Neurology, IstanbulUnited KingdomGavin Giovannoni, Institute of Neurology, Queen Square House, London; Clive Hawkins, Dept of Neurology, University Hospital of North Staffordshire, Hartshill, Stoke-on-Trent; Mohammed Sharief, Multiple Sclerosis Research Clinic, Department of Clinical Neurosciences, Guy's Hospital, London; Dr. Basil Sharrack, Department of Neurology, Royal Hallamshire Hospital,SheffieldSafety Monitoring CommitteeC Confavreux, O Lyon-Caen, France; J Ware, G Burton Saibert, USA Phase 3 DEFINE Study Investigators ( Identifier: NCT00420212) – parent of the ENDORSE extension studyCO-INVESTIGATORSAustraliaMichael Barnett, MS Clinical Trials Research Unit, Camperdown, NSW; Mark Paine, Dept. of Clinical Neurosciences, Fitzroy, VIC; Jeannette Lechner-Scott, Dept. of Medicine and Neurology, John Hunter Hospital, New Lambton, NSW; Roy Beran, Chatswood, NSW; Caron Chapman, Neurosciences Dept., Geelong, VIC; Raymond Schwartz, Kogarah, NSW; Helmut Butzkueven, Melbourne, VIC; Reynolds Casse, Adelaide, SA; Richard Macdonell, N-CRESS Occupational Therapy Building, Heidelberg, VICAustriaThomas Berger, Innsbruck; Franz Fazekas, Styria; Gerhard Ransmayr, Abt. Neurologie und Psychiatrie, Linz; Karl Vass, W?hringer Gürtel, ViennaBelgiumShibeshih Belachew, Dept. of Neurology, Liège; Peter Paul De Deyn, Campus Middelheim, Antwerpen; Danny Decoo, West Vlaanderen; Bénédicte Dubois, Flemish Brabant; Robert Medaer, Universitaire Campus, Diepenbeek, Limburg; Pierrette Seeldrayers, Hainaut; Christian Sindic, Brussels; Luc Vande Gaer, Hechtel-Eksel; Ludo Vanopdenbosch, BruggeBosnia HerzegovinaSanja Grgic, Clinical Centre Banja Luka, Department of Neurology, Banja LukaCanadaAmit Bar-Or, Montreal, QC; Virender Bhan, Halifax, NS; Jean-Pierre Bouchard, Quebec, QC; Suzanne Christie, Ottawa, ON; Pierre Grammond, Lévis, QC; Fran?ois Jacques, Gatineau, QC; Felix Veloso, Regina, SK; Galina Vorobeychik, Burnaby, BCCroatiaVesna Brinar, Zagreb; Vida Demarin, Zagreb; Josip Rude?, Cambierieva, Primorje-Gorski Kotar; Silva Soldo-Butkovi?, Clinic of Neurology, Osijek-Baranja; Ranka Baraba Vurdelja, Dept. of Neurology, ZagrebCzech RepublicZdeněk Ambler, Plzeň; David Dole?il, Slezska Nemocnice v Opave, Neurologicke Oddeleni, Opava; Eva Havrdova, Karlovo námesti, Praha; Petr Kanovsky, I.P. Pavlova, Olomouc, Olomouck? Kraj; Eva Meluzinova, Praha; Ji?í Nova'k, Ostrava-Moravska, Ostrava; Ivan Rektor, Peka?ská, Jihocesky Kraj; Ondrej Skoda, P.O. Neurologické Oddelení, Jihlava; Marta Vachová Duchcovská, Severocesky KrajFranceWilliam Camu, H?pital Gui de Chauliac, Montpellier; Pierre Clavelou Antoanela, H?pital Gabriel Montpied, Service de Neurologie Clermont Ferrand, Dunant; Irène Coman, H?pital Avicenne, Service de Neurologie du Prof. Carpentier, Bobigny; Christian Confavreux, H?pital Neuro-cardiologique Pierre Wertheimer, Lyon; Gilles Edan, H?pital Pontchaillou, Rennes; Olivier Gout, Fondation Ophtalmologique Adolphe Rothschild, Paris; Christine Lebrun-Frenay, H?pital Pasteur, Nice; Anne-Caroline Papeix, H?pital Pitié-Salpêtrière, Paris; Patrick Vermersch, H?pital Roger Salengro, LilleGermanyKatrin Bachus-Banaschak, Berlin; Martin Berghoff, Hessen; Florian Bethke, Abteilung für Neurologie, Nordrhein-Westfalen; Hans-Jürgen Boldt, Berlin; Andrew Chan, Bochum, Nordrhein-Westfalen; Hans-Christoph Diener, Essen, Nordrhein-Westfalen; Ilonka Eisensehr, München, Bayern; Peter Emrich, Hamburg; Bernd Griewing, Bad Neustadt/Saale, Bayern; Judith Haas, Abt. für Neurologie, Berlin; Christoph Heesen, Hamburg; Frank Hoffmann, Klink für Neurologie, Halle, Sachsen-Anhalt; Andreas Hufnagel, Düsseldorf, Nordrhein-Westfalen; Fedor Heidenreich, Niedersachsen; Ingo Kleiter, Regensburg, Bayern; Wilfried Lüer, Berlin; Silke Marckmann-B?enke, Minden, Nordrhein-Westfalen; Martin Marziniak, Münster, Nordrhein-Westfalen; Martin Stangel, Hannover, Niedersachsen; Patrick Oschmann, Neurologische Klinik, Bayreuth, Bayern; Thorsten Rosenkranz, Hamburg; Hauke Schneider, Klinik und Poliklinik für Neurologie, Dresden, Sachsen; Veneta Siefjediers, Berlin; Joachim Springub, Westerstede, Niedersachsen; Martin Stangel; Florian St?gbauer, Niedersachsen; Florian Then Bergh, Konservatives Zentrum Neurologie, Leipzig; Klaus Tiel-Wilck, Neurologisches Facharztzentrum, Berlin; Konstanze Tinschert, Jena, ThuringenGreeceNikolaos Grigoriadis, Thessaloniki, Macedoni; Clementine Karageorgiou, Athens, Attica; Athanssios Kyritsis, University Campus, Ioannina; Alexandros Papadimitriou, Dept. of Neurology, Athens, Attica; Thomas Thomaides, Neurology Clinic, Athens, Attica; Nicholas Vlaikidis, Exochi-Asvestochori, Thessaloniki, MacedoniGuatemalaLuis Fernando Salguero Gonzalez, Edificio Multimedica, Guatemala City; David Yaxcal Chon, Clinica Las Americas, Oficina, Guatemala; Hugo Alfredo Ordo?ez Sarg, Hospital Itzamna, GuatemalaIndiaCS Agrawal, Sir Ganga Ram Hospital, Department of Neurology, New Delhi; Madhuri Behari, All India Institute of Medical Sciences, New Dehli; Velmurugendran Cu, Sri Ramachandra Medical and Research Institute Porur, Nadu; Shamsher Dwivedee, Vidhyasagar Institute of Mental Health and Neurosciences, Nehru Nagar, New Delhi; Sudhir Kothari, Poona Hospital and Research Center, Pune, Maharashtra; Rahul Kulkarni, Deenanath Mangeshkar Hospital and Research Centre, Erandawane, Dept. of Neurology, Pune, Maharashtra; Suman Kushwaha, Institute of Human Behaviour and Allied Science, Dilshad Garden, Shahdara , Delhi; AK Meena, Nizams Institute of Medical Sciences, Punjagutta, Andhra Pradesh; MM Mehndiratta, G B Pant Hospital, J L N Marg, Dept. of Neurology, New Delhi; Subhash Chandra Mukherjee, B.P. Poddar Hospital and Medical Research Limited, Kolkata. West Bengal; Lekha Pandit, K.S. Hegde Medical College and Hospital, Department of Neurology Deralakatte, Mangalore, Karnataka; Arun Shah, T N M C and B Y L Nair Charitable Hospital, Neurology Department, Mumbai, Maharashtra; Rakesh Shukla, CSM Medical University, Department of Neurology. Uttar Pradesh; K Vijayan, Kovai Medical Center and Hospitals Department of Neurology, Coimbatore, Tamil NaduIsraelAnat Achiron, Multiple Sclerosis Center Sheba Medical Center, Tel Hashomer; Shlomo Flechter, Multiple Sclerosis Clinical Research and Therapy Service, Assaf Harofeh Medical Centre, Zerifin Beer Yaakov; Ron Milo, Barzilai Medical Center, Ashkelon; Adi Vaknin-Dembinsky, Hadassah Medical Organization, Kiryat Hadassah Neurology Dept. JerusalemItalyCarlo Pozzilli, RomeMacedoniaVera Daskalovska, University clinic for neurology, SkopjeMexicoFreddy Guillermo Castro Farfan, Delegación Miguel Hidalgo, Distrito Federal; Ricardo Alberto Rangel Guerra, Colonial Obispado, Monterrey, Nuevo Leon; Ildefonso Rodriguez Leyva, Colonia Zona Universitaria, San Luis Potosi; José Luis Oropeza de Alba, Hospital N278, Torre de Especialidades, Guadalajara, Jalisco; Raúl Arcega Revilla, Colonia Gabriel Pastor, Puebla; Jose Flores Rivera, Colonia La Fama, Distrito FederalMoldovaMihail Gavriliuc, Institutul de Neurologie si Neurochirurgie, Chisinau; Stanislav Groppa, Centrul National Practico-Stiintific in Domeniul Medicinii de Urgenta, Chisinau; Olesea Odainic, Institutul de Neurologie si Neurochirurgie, Dep. Neurologie, ChisinauNetherlandsE.A.C.M. Sanders, Breda, Noord-Brabant; Raymond Hupperts, Sittard-Geleen, LimburgNew ZealandDeborah Mason, Christchurch; Paul Timmings, Anglesea Clinic, Hamilton; Ernest Willoughby, Grafton, AucklandPolandAnna Czlonkowska, Warszaw, Mazowieckie; Malgorzata Dorobek, Klinika Neurologii, Warszaw, Mazowieckie; Wieslaw Drozdowski, Bia?ystok, Podlaski; Waldemar Fryze, Gdańsk, Pomorskie; Hanka Hertmanowska, Fabianowska-OS. Pogodne, Wielkopolskie; Magdalena Kleczkowska, Gdańsk, Pomorskie; Jan Kochanowicz, Bialystok, Podlaskie; Hubert Kwieciński, Warszaw, Mazowieckie; Przemyslaw Nowacki, Szczecin, Zachodniopomorskie; Ryszard Podemski, Oddzial Kliniczny Neurologii, Wroc?aw, Dolnoslaskie; Andrzej Potemkowski, Szczecin, Zachodniopomorskie; Krzysztof Selmaj, Oddzial Kliniczny Neurologii, ?ód?, Lodzkie; Zbigniew Stelmasiak, Katedra i Klinika Neurologii Akademii Medycznej w Lublin, Lublin, Dolnoslaskie; Andrzej Wajgt, Katowice, Slaskie; Tomasz Zielinski, Katowice, SlaskieMacedoniaVera Daskalovska, Clinic for Neurology, Department of Multiple Sclerosis, SkopjeRomaniaAlexandru Ovidiu Bajenaru, Spitalul Universitar de Urgenta Bucuresti, Clinica de NeurologieBucuresti, BucurestI; Fior Dafin Muresanu, Spitalul Clinic Judetean de Urgenta Cluj-Napoca, Neurologie Cluj-Napoca, Cluj; Sanda Maria Nica, Spitalul Clinic Colentina, Dept. Neurologie, Bucuresti; Mihaela Adriana Simu, Spitalul Clinic Judetean de Urgenta Timisoara, Clinica de Neurologie, Timisoara, TimisSerbiaSvetlana Mileti? Drakuli?, Kragujevac; Congor Nadj, Novi Sad; Dragana Obradovic, Belgrade; Slobodan Vojinovic, NisSlovakiaPeter Tur?áni, Bratislava; Edita Kahancová, Kosice; Egon Kurca, ?ilina; L'ubomir Lis?, Bratislava; Viliam Krajnak, Ru?omberokSouth AfricaFrans Badenhorst, Parow, Western Cape; Judy Green, St Augustine's Medical Mews, Durban, KwaZulu-Natal; Jeannine Heckmann, Div. of Neurology, New Groote Schuur Hospital, Cape Town, Western Cape; Michael Isaacs, Medical and Dental Centre, Rosebank, GautengSwitzerlandLudwig Kappos, Universit?tsspital Basel, Neurology-Neurosurgical Policlinic, Basel; Michael Linnebank, Universit?tsspital Zürich, Neurologische Klinik, Zürich; Stefanie Müller, Kantonspital Sankt Gallen, Klinik für NeurologieSt. Gallen, St. GallenUkraineNataliya Buchakchyys'ka, Dept. of Neurology, Zaporozhye; Alla Goloborodko, Dept. of Neurosurgery Acad., Odessa; Tetyana Kobys, Kyiv; Volodymyr Lebedynets, Dept. of Neurology Kharkiv; Nataliya Lytvynenko, Dept. of Neurology and Neurosurgery, Poltava; Tetyana Nehrych, Lviv; Igor Pasyura, Neurology Dept, Kharkiv; Tatyana Ryabichenko, Kyiv; Nataliya Voloshina, KharkivUnited KingdomMartin Duddy, Royal Victoria Infirmary, Department of Neurology, Newcastle upon Tyne; Clive Hawkins, University Hospital of North Staffordshire, Hartshill, Stoke-on-Trent; Richard Nicholas, Charing Cross Hospital, London; Jacqueline Palace, John Radcliffe Hospital, Department of Clinical Neurology, Oxford; Basil Sharrack, Royal Hallamshire Hospital, Department of Neurology, Sheffield; Eli Silber, King's College Hospital, Department of Neurology, London; Ben Turner, Royal London Hospital, Department of Neurology, Whitechapel, LondonUnited StatesAnn Camac, Lahey Clinic, Lexington, MA; Warren Chumley, Associates in Neurology, PSC, Lexington, KY; Heidi Crayton, Multiple Sclerosis Center of Greater Washington, Vienna, VA; Shanker Dixit, Lovelace Scientific Resources, Inc., Henderson, NV; Keith Edwards, Empire Neurology, PC, Latham, NY; Jeffrey English, Multiple Sclerosis Center of Atlanta, Atlanta, GA; Steven Freedman, Raleigh Neurology Associates, Raleigh, NC; Norman Gordon, CNS Research, Inc., East Providence, RI; Suzanne Gazda, Integra Clinical Research, LLC, 4242 Medical Drive, Building 6, Suite 6100, San Antonio, TX; Lawrence Goldstick, Neurology Specialists, Inc., Dayton, OH; P. Christopher Gottschalk, Yale University School of Medicine/Yale Center for Multiple Sclerosis Treatment, New Haven, CT; Erica Grazioli, Hamot Center for Clinical Research, Erie, PA; William Grainger, Clinical Research Advantage/Neurological Physicians of Arizona, Gilbert, AZ; Barbara Green, Saint John's Mercy Medical Center, Div. of Neurology, Saint Louis, MO; Bart Grelinger, Neurology Consultants of Kansas, LLC, Wichita, KS; Mark Gudesblatt, South Shore Neurology Associates, Inc., Patchogue, NY; Ajay Gupta, Fort Wayne Neurological Center, Fort Wayne, IN; Ghazala Hayat, St. Louis University, Dept. of Neurology and Psychiatry, Saint Louis, MO; Barry Hendin, Phoenix Neurological Associates, Ltd, Phoenix, AZ; Lily Jung Henson, Swedish Neuroscience Institute, Seattle, WA; Afif Hentati, North Shore University Health System, Evanston, IL; Craig Herrman, Josephson Wallack Munshower Neurology, PC, Indianapolis, IN; Arthur Itkin, Neurologic Associates, Ltd., Palos Heights, IL; Todd Janus, Iowa Health Des Moines, Des Moines, IA; Lloyd Kasper, Dartmouth Hitchcock Medical Center, Dept. of Neurology, Lebanon, NH; Ellen Lathi. Saint Elizabeth's Medical Center of Boston, Boston, MA; Ellen Mowry, University of California at San Francisco, MS Center, San Francisco; Gareth Parry, University of Minnesota, Minneapolis, MN; Allan Perel, Alpha Neurology, Staten Island, NY; T. Hemanth Rao, Neurological Institute, PA, Charlotte, NC; Peter Riskind, University of Massachusetts Memorial Health Care, Worcester, MA; Syed Rizvi, Rhode Island Hospital, Providence, RI; Howard Rossman, Michigan Institute for Neurological Disorders, Farmington Hills, MI; Thomas Scott, Allegheny Neurological Associates, Pittsburgh, PA; S. James Shafer, Vero Beach Neurology, Vero Beach, FL; James Storey, Jr., Upstate Clinical Research, LLC, Albany, NY; Ben Thrower, Shepherd Center, Inc., Atlanta, GA; Michael Rossen, Springfield Neurology Associates, LLC, Springfield, MA, Carlo Tornatore, Georgetown University Hospital, Dept of Neurology, Washington, DC; William Tosches, Neurology Associates, 54 Hopedale Street, Hopedale, MA; Lori Trefts, Hampton Roads Neurology, Newport News, VA; Anthony Turel, Jr., Penn State Hershey Neuroscience Clinics, Hershey, PA; Bianca Weinstock-Guttman, Buffalo General Hospital, Jacobs Neurological Institute, Buffalo, NYAdvisory CommitteeRalf Gold, (Coordinating Investigator and Chairperson), Dept. of Neurology, St. Josef Hospital/Ruhr-University Bochum, Bochum, Germany; Ludwig Kappos, Universit?tsspital Basel, Neurology-Neurosurgical Policlinic, Basel, Switzerland; Douglas Arnold, NeuroRx Research, Montreal, Quebec, Canada; Amit Bar-Or, Montreal Neurological Institute and Hospital, Montreal, Quebec, Canada; Gavin Giovannoni, Department of Neurology, Barts and The London NHS Trust, Royal London Hospital, Whitechapel, London, United Kingdom; Krzysztof Selmaj, Department of Neurology, Medical University of Lodz, Lodz, Poland; Katherine T Dawson, Senior Medical Director, Biogen Idec, Cambridge, MA; Phillip Gallacher, Clinical Program Lead, Biogen Idec, Cambridge, MA; Carole Milla, Clinical Trial Manager, Biogen Idec, Cambridge, MA; Minhua Yang, Project Statistician, Biogen Idec, Cambridge, MAData Safety Monitoring CommitteeJack Antel, (Chairperson), Neurology; Montreal Neurological Hospital, Montreal, Quebec, Canada; George Bakris, Nephrology; University of Chicago, Pritzker School of Medicine, Chicago, IL; Raymond Chung, Hepatology; Massachusetts General Hospital, Boston, MA; Peter R Kowey, Cardiology, Jefferson Medical College, Wynnewood, Pennsylvania; Chris Polman, Neurology; VU Medical Center, Amsterdam, The Netherlands; John Richert (thru February 2010), Neurology, National Multiple Sclerosis Society, New York, NY; Burt Seibert, Independent Biostatistician; Statistical Services Network, Plaistow, NH; James Ware, Statistics, Harvard School of Public Health, Boston, MAIndependent Neurology Evaluation CommitteeDavid Brandes, Northridge Multiple Sclerosis Center, Northridge, CA; David Brassat, INSERM U.563, H?pital Purpan, Toulouse, France; Bruce Cohen, Fineberg School of Medicine, Chicago, IL; Ricarda Diem, University of the Saarland, Homburg/Saar, Germany; Myla Goldman, University of Virginia, Charlottesville, VA; Robert Herndon, University of Mississippi Medical Center, Jackson, MS; Aaron Miller, Mount Sinai Medical Center, New York, NY; Hayrettin Tumani, University of Ulm, Ulm, GermanyPhase 3 CONFIRM Study Investigators ( Identifier: NCT00451451) – parent of the ENDORSE extension studyCO-INVESTIGATORSAustraliaChristopher Kneebone, North Terrace Emergency Block, AdelaideBelarusAliaksandr Fedulau, Minsk; Sergey Likhachev, Minsk; Elena Mikhailova, General and Clinical Pharmacology, Gomel, Homyelrskaya; Halina Naumova, Vitebsk, VitsyebskayaBelgiumDanny Decoo, West-Vlaanderen; Christian Sindic, Brussels; Luc Vande Gaer, Hechtel-EkselBosnia HerzegovinaSanja Grgic, Clinic for Neurology, Clinical Center, Banja Luka; Osman Sinanovic, University Clinical Center Tuzla, Department of Neurology, Tuzla; Enra Mehmedika Suljic, Clinic of Neurology, Clinical University Centre Sarajevo, SarajevoBulgariaNadezhda Deleva, First Neurology Clinic, Multiprofiled Hospital for Active Treatment “Sveti Marina”, Varna; Dimitar Georgiev, University Specialized Hospital for Active Treatment in Neurology and Psychiatry “St Naum”, Sofia; Lyubomir Haralanov, Clinic of Neurology, Specialized Hospital for Active Treatment in Cardiovascular Diseases, Sofia; Sonyia Ivanova, University Specialized Hospital for Active Treatment in Neurology and Psychiatry “Sveti Naum”, Sofia; Ivan Manchev, Clinic of Neurology, Multiprofiled Hospital for Treatment, Stara Zagora; Dimitar Minchev, Second Neurology Clinic, Multiprofiled Hospital for Active Treatment “Sveta Marina”, Varna; Paraskeva Stamenova, MHAT “Tsaritsa Yoanna”, Sofia; Ivailo Tournev, University Multiprofiled Hospital for Active Treatment “Alexandrovska” Sofia; Elena Vacheva, First Neurology Ward, Multiprofiled Hospital for Active Treatment, Rousse; Zahari Zahariev, MHAT “Sveti Georgi”, PlovdivCosta RicaRoberto Vargas Howell, Barrio Los Yoses, San Pedro Montes de Oca, San José; Alexander Parajeles Vindas, Del Bar La Deportiva, San Francisco, HerediaCanadaAmit Bar-Or, Montreal, QC; Gregg Blevins, Edmonton, AB; Marcelo Kremenchutzky, London, ON; Felix Veloso, Regina, SK; Norbert Witt, Northwest, Edmonton, ABCroatiaMario Habek, Zagreb; Josip Rude?, Cambierieva, Primorje-Gorski Kotar; Silva Soldo-Butkovi?Clinic of Neurology, Josipa Huttlera 4, Osijek, Osijek-Baranja; Ranka Baraba VurdeljaDept. of Neurology, ZagrebCzech RepublicDavid Dole?il, Praha; Eva Havrdova, Praha; Dr. Ji?í Nova'k, Ostrava; Daniel Vaclavik, North MoraviaEstoniaKatrin Antsov, Parnu; Katrin Gross-Paju, Tallinn; Sulev Haldre, Tartu; Alla Palu, Kuressaare; Toomas Toomsoo, TallinnFranceAbdullatif Al Khedr, Service Neurologie, Amiens, Picardie; William Camu, Montepellier; Jér?me De Seze, Strasbourg, Alsace; Marc Debouverie, Nancy, Lorraine; Gilles Defer, Caen, Basse Normandie; Pierre Labauge, N?mes, Provence Alpes Cote D'Azur; Thibault Moreau, Dijon, Bourgogne; Lucien Rumbach, Besancon, Franche-ComteGermanyKlemens Angnstwurm, Regensburg, Bayern; Heike Benes, Schwerin, Mecklenburg-Vorpommern; Achim Berthele, München, Bayern; Hans-Jürgen Boldt, Berlin; Angelika Christopher, Berlin; Tobias Derfu?, Neurologische Klinik, Erlangen, Bayern; Ilonka Eisensehr, München, Bayern; Peter Emrich, Hamburg; Wolfgang Feneberg, Berg, Starnberger See, Bayern; Frank Hoffmann, Klink für Neurologie, Halle, Sachsen-Anhalt; Reinhard Hohlfeld, Klinische für Neuroimmunologie, Müchen; Reinhard Hüntemann, Bochum, Nordrhein-Westfalen; Boris-Alexander Kallmann, Bamberg, Bayern; Bernd Kieseier, Düsseldorf, Nordrhein-Westfalen; Ingo Kleiter, Regensburg, Bayern; Harald Landefeld, Essen, Nordrhein-Westfalen; Wilfried Lüer, Berlin; Sabine Masri, Berlin-Tempelhof, Berlin; Mathias M?urer, Neurologische Klinik, Erlangen, Bayern; Gereon Nelles, K?ln; Patrick Oschmann, Neurologische Klinik, Bayreuth, Bayern; Christine Paschen, Schwerin, Mecklenburg-Vorpommern; Gerd Reifschneider, Erbach; Michael Sailer, Magdeburg, Sachsen-Anhalt; Sebastian Schimrigk, Neurologische Klinik, Lüdenscheid; Mechthild Spiegel-Meixensberger, Johannisplatz 1, Leipzig, Sachsen; Andreas Steinbrecher, Regensburg, Bayern; Brigitte Storch-Hagenlocher, Heidelberg, Baden-Wuerttemberg; Bj?rn Tackenberg, AG Klinische Neuroimmunologie, Marburg, Hessen; Klaus Tiel-Wilck, Neurologisches Facharztzentrum, BerlinGreeceClementine Karageorgiou, Athens, Attica; Panagiotis Papathanasopoulos, Rion, Patras; Thomas Thomaides, Neurology Clinic, Athens, Attica; Nicholas Vlaikidis, Exochi-Asvestochori, Thessaloniki, MacedoniIndiaDeepak Arjundas, Vijaya Health Centre, Vadapalani, Chennai; Madhuri Behari, All India Institute of Medical Sciences, Ansari Nagar, New Delhi; Shalin Dipinkumar Shah, Neurology Clinic, Ellisbridge, Ahmedabad, Gujarat; Amitabha Ghosh, Apollo Gleneagles Hospitals, Kolkata, West Bengal; Pahari Ghosh, Sri Aurobindo Seva Kendra, Jodhpur Park, Kolkata; Nasli Rustom Ichaporia, Jehangir Clinical Development Centre Pvt. Ltd, Pune; Dheeraj Khurana, Post Graduate Institute of Medical Education & Research, Department of Neurology, Chandigarh, Punjab; Rahul Vitthal Kulkarni, Deenanath Mangeshkar Hospital and Research Centre, Department of Neurology, Erandawane, Pune, Maharashtra; Man Mohan Mehndiratta, G.B. Pant Hospital, Department of Neurology, New Delhi; Neeta Abhay Mehta, Neeta Mehta Clinic Rizvi Nagar, Santacrus, Mumbai; Usha Kant Misra, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Department. of Neurology, Lucknow; Joy Dev Mukherji, Max Super Speciality Hospital, Saket, New Delhi; Shankara Nellikunja, Mallikatta Neuro Center, Kadri, Mangalore, Karnataka; Suresh Kumar Radhakrishnan, Amrita Institute of Medical Sciences and Research Centre, Ponekkara, Elamakkara, Kochi; Abdu Salem, Baby Memorial Hospital, Calicut, Kerala; Prahlad Kumar Sethi, Sir Ganga Ram Hospital, Department of Neurology, Old Rajinder Nagar, New Delhi; Gagandeep Singh, DMC Hero Heart Institute, Department of Neurology, Tagore Nagar; Civil Lines, Ludhiana, Punjab; Maneesh Kumar Singh, Avadh Hospital & Heart Centre, Singar Nagar, Lucknow; Yash Pal Singh, Christian Medical College & Hospital, Department of Neurology, Ludhiana; Rangasetty Srinivasa, M.S. Ramaiah Memorial Hospital, Gokula Metropolis Clinical Research Centre, Bangalore; Krishnan Vijayan, Kovai Medical Center and Hospital, Department of Neurology, CoimbatoreIrelandMichael Hutchinson, St. Vincent’s University Hospital, Elm Park, Donnybrook, Dublin; Bernard Sweeney. Cork University Hospital, CorkIsraelRonit Gilad, E. Wolfson Medical Center, Tel Giborim, Holon; Radi Shahien, Rebecca Ziv Hospital, SafedLatviaMaija Metra, Riga; Anita Paegle, RigaMacedoniaVera Daskalovska, Clinic for Neurology, Department for Multiple Sclerosis, SkopjeMexicoCesar Delgado, Unidad de Investigacion en Salud de Chihuahua SC, Chihuahua; Juan Escamilla, Hospital Universitario Jose Eleuterio Gonzalez, Monterrey, Nuevo Leon; Bruno Esta?ol, Instituto, Nacional de Ciencias Medicas y Nutricion Salvador Zubiran (INCMNSZ), Tlalpan City; Neyla Lopez, Hospital General de Mexico, Doctores City; Miguel Angel Macias, Fundacion Mexicana para le Esclerosis Multiple AC, Guadalaraja, Jalisco; Guillermo Punzo, Clinica Neurologica de Morelia, Morelia, Michoacan; Sandra Qui?ones, Hospital Obregon, Cuauhtemoc City; Mariela Renteria, Hospital Angeles Ciudad Juarez de Chihuahua SC, Unidad de Investigacion en Salud, Ciudad Juarez; Chihuahua’ Jose Santos, Medica SUR CIF-BIOTEC, Tlalpan CityMoldovaMihail Gavriliuc, Institutul de Neurologie si Neurochirurgie, Dep. Neurologie, Chisinau; Stanislav Groppa, Centrul National Practico-Stiintific in Domeniul Medicinii de Urgenta, Chisinau; Olesea Odainic, Institutul de Neurologie si Neurochirurgie, Dep. Neurologie, ChisinauNew ZealandPaul Timmings, HamiltonPolandAnna Czlonkowska, Mazowieckie, MRI - Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Warszawa; Malgorzata Dorobek, Jaros?aw Pniewski, Klinika Neurologii, Warszawa, Mazowieckie; Wieslaw Drozdowski, Bia?ystok, Podlaskie, Centrum Medyczne Diagnostyka, Bialystok; Waldemar Fryze, Oddzia? Neurologiczny i Oddzia? Udarowy, MRI - Akademickie Centrum Kliniczne AM w Gdansku, Gdansk; Hanka Hertmanowska, Fabianowska-OS. Plewiska K/Poznania, Wielkopolskie, Poznan; Anna Kaminska, Klinika Neurologii, MRI-Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Warszawa; Magdalena Kapelusiak-Pielok, Poznań, Wielkopolskie; Magdalena Kleczkowska, Gdańsk, Pomorskie, Pomorskie Centrum Medyczne, ul. Polanki, Gdansk; Jan Kochanowicz, Bialystok, Podlaskie; Hubert Kwieciński, Klinika Neurologii, MRI-Samodzielny Publiczny Centralny Szpital Kliniczny w Warszawie, Warszawa; Jacek Losy, Katedra Neurologii, Zak?ad Neuroimmunologii Klinicznej, Poznań, Wielkopolskie; Przemyslaw Nowacki, Katedra i Klinika Neurologii z Pododdzia?em Udarowym, Szczecin, Zachodniopomorskie; Walenty Nyka, Klinika Neurologii Doros?ych, Gdańsk, Pomorskie; Krystyna Pierzchala, Zabrze, Slaskie; Ryszard Podemski, Klinika Neurologii, Wroc?aw, Dolnoslaskie, MRI-Zaklad Radiologii Ogolnej, Zabiegowej i Neuroradiologii, Akademicki Szpital Kliniczny we Wroclawiu, Wroclaw; Andrzej Potemkowski, Szczecin, Zachodniopomorskie; Krzysztof Selmaj, Oddzial Kliniczny Neurologii, Lodzkie, MRI-Zak?ad Radiologii, Samodzielny Publiczny Szpital Kliniczny, Uniwersytecki Szpital Kliniczny, Lodz; Zbigniew Stelmasiak, Klinika Neurologii z Pododdzia?em Udarowym i Wczesnej Rehabilitacji Poudarowej Lublin, Dolnoslaskie, MRI- Zaklad Opieki Zdowotnej MSWiA, Pracownia Tomografii Komputerowej i Rezonansu Magnetycznego, Lublin; Andrzej Szczudlik, Kraków, Malopolskie; Andrzej Tutaj, Olsztyn, Warminsko-Mazurskie; Andrzej Wajgt, I Katedra i Klinika Neurologii, Slaskie, Helimed Diagnostic Imaging, Katowice; Tomasz Zielinski, Katowice, SlaskiePuerto RicoAngel Chinea, Caribbean Center for Clinical Research, Centro Internacionale de Mercadeo, GuaynaboRomaniaRodica Balasa, T?rgu Mure?, Mures; Valentin Ionescu-Dimancea, Bucresti; Petru Mihancea, Oradea; Cristian Popescu, Iasi; Liviu Codrut Protosevici, BucurestiSerbiaSvetlana Mileti? Drakuli?, Kragujevac; Congor Nadj, Novi Sad; Ranko Raicevic, Belgrade; Slobodan Vojinovic, NisSlovakiaEdita Kahancová, Kosice; Egon Kurca, ?ilina; L'ubomir Lis?, Bratislava; Peter Tur?áni, BratislavaSpainRafael Arroyo, Ala Sur- Unidad de enfermedades desmielinizantes, Servicio Neurologia, calle Doctor Martín Lagos, Madrid; Oscar Fernández, Servicio de Neurología, Avenida Carlos Haya, Planta Málaga, Malaga; Cristina Guijarro, Servicio Neurologia- Hospital de dia 1a Planta, Cuidad Universitaria, Madrid; Guillermo Izquierdo, Policlínico, Avenida Doctor Fedriani, Sevilla, Andalucía; Xavier Montalbán, Antiga Escola d'Infermeria, Barcelona; Celia Oreja-Guevara, Servicio de Neurología, Hospital General - Planta 11, Madrid; Jose Maria Prieto, Travesia de la Choupana, Santiago de Compostela, La Coruna; Fernando Sanchez Lopez, Servicio Neurologia, Avenida de America, Edificio de Especialidades Médicas-5? Planta, CórdobaUkraineNataliya Buchakchyys'ka, Dept. of Neurology, Zaporozhye; Galyna Chmyr, Ivano-Frankivsk; Alla Goloborodko, Dept. of Neurosurgery, Odessa; Nataliya Grytsay, Dept. of Neurology and Neurosurgery, Poltava; Tetyana Kobys, Kyiv; Grygory Kushnir, Simferopol, Crimea; Volodymyr Lebedynets, Dept. of Neurology, Kharkiv; Nataliya Lytvynenko, Dept. of Neurology and Neurosurgery, Poltava; Sergii Moskovko, Dept. of Nervous Diseases, Vinnitsa, Vinnytsya; Tetyana Nehrych, Lviv; Borys Palamar, Neurology Dept., Kyiv; Igor Pasyura, Neurology Dept., Kharkiv; Tatyana Ryabichenko, Kyiv; Nataliya Voloshina, KharkivUnited StatesMichelle Apperson, University of California, Davis Medical Center, Dept. of Neurology, Sacramento, CA; Angela Applebee, University of Vermont, Burlington, VT; Stephen Asher, Neurological Associates, Meridian, ID; Ricardo Ayala, AMO Corporation, Tallahassee, FL; Donald Ayres, Upper Valley Neurology Neurosurgery, Ayers and Associates Clinical Trials, Lebanon, NH; S. Ausim Azizi, Temple University Hospital, Philadelphia, PA; Matthew Baker, Collier Neurologic Specialists, LLC, Naples, FL; Brendan Bauer, Northern Ohio Neuroscience, LLC, Bellevue, OH; Roberto Bomprezzi, Barrow Neurological Institute, Saint Joseph's Hospital and Medical Center, Phoenix, AZ; Richard Buckler, Pivotal Clinical Research, LLC, Souderton, PA; Walter Carlini, Medford Neurological and Spine Clinic, Medford, OR; Stanley Cohan, Providence Multiple Sclerosis Center, Portland, OR; Giles Crowell, Clinical Trials of America, Inc., Winston-Salem, NC; Keith Edwards, Empire Neurology, PC, Bennington, VT; Geoffery Eubank, Neurological Research Institute, Neurological Research Institute, Columbus, OH; Warren Felton III, Virginia Commonwealth University, Richmond, VA; Patricia A. Fodor, Colorado Springs Imaging, Colorado Springs, CO; John Foley, Rocky Mountain Multiple Sclerosis Clinic, Salt Lake City, UT; Corey Ford, University of New Mexico, MIND Institute, 1101 Yale Boulevard Northeast, Albuquerque, NM; Mary Forester, Dean Clinic, Madison, WI; Edward Fox, Central Texas Neurology, Round Rock, TX; Robert Fox, Cleveland Clinic Foundation, Center for Neurological Disorders, Cleveland, OH; Steven Freedman, Raleigh Neurology Associates, Raleigh, NC; George Garmany, Jr., Alpine Clinical Research Center, Boulder, CO; Suzanne Gazda, Integra Clinical Research, LLC, San Antonio, TX; Daniel Giang, Loma Linda University Medical Center, Dept. of Neurology, Loma Linda, CA; Braeme Glaun, Sinai Neurology Associates, Baltimore, MD; Scott Gold, Multiple Sclerosis Center of Melbourne, Melbourne, FL; Malcolm Gottesman, Winthrop University Hospital/Clinical Trials Center, Mineola, NY; Mark Gudesblatt, South Shore Neurology Associates, Inc., Patchogue, NY; Joseph Herbert, New York University Hospital for Joint Diseases, New York, NY; Allan Herskowitz, Neuroscience Consultants, LLC, Miami, FL; William Honeycutt, Neurology Associates, PA, Maitland, FL; John Huddlestone, Neurology and Neurosurgery Associates of Tacoma, PLLC, Tacoma, WA; Richard Hull, North Alabama Neuroscience Research Associates, Huntsville, AL; Samuel Hunter, Advanced Neurosciences Institute, Pharmaceutical Research Center, Franklin, TN; George Hutton, Maxine Mesinger Multiple Sclerosis Clinic; Baylor College of Medicine, Health Sciences Center, Houston, TX; Dina Jacobs, University of Pennsylvania Medical Center, Philadelphia, PA; Mark Janicki, Indiana Neuroscience Associates, Indianapolis, IN; Bhupendra Khatri, Saint Luke's Medical Center, Center for Neurological Disorders, Milwaukee, WI; Revere Philip Kinkel, Beth Israel Deaconess Medical Center, Boston, MA; Mariko Kita, Virginia Mason Medical Center, Lindeman Pavilion, Seattle, WA; Stanley Krolczyk, University of South Florida, Dept. of Neurology, Tampa, FL; Lauren Krupp, State University of New York at Stony Brook, Dept. of Neurology, Stony Brook, NY; Christopher LaGanke, North Central Neurology Associates, PC, Cullman, AL; Michael Levin, University of Tennessee-Memphis, Department of Neurology, Memphis, TN; Jonathan Licht, Coordinated Clinical Research, Neurology, La Jolla, CA; Christopher Luzzio, University of Wisconsin Hospital-Madison, Pharmaceutical Research Center, Madison, WI; Sharon Lynch, University of Kansas Medical Center, Landon Center on Aging, Kansas City, KS; David Mattson, Indiana University School of Medicine, Indianapolis, IN; Daniel Mikol, University of Michigan, Taubman Center, Ann Arbor, MI; Tamara Miller, Advanced Neurology of Colorado, Fort Collins, CO; Alireza Minagar, Louisiana State University Health Sciences Center in Shreveport, Shreveport, LA; Galen Mitchell, University of Pittsburgh, Department of Neurology, Pittsburgh, PA; Harold Moses, Jr., Vanderbilt Multiple Sclerosis Center, Nashville, TN; Donald Negroski, Negroski Sutherland and Hanes Neurology, Sarasota, FL; Stephen Newman, Center for Headache Care and Research at Island Neurological Associates, P.C., Plainview, NY; Gabriel Pardo, Mercy Multiple Sclerosis Center of Oklahoma Mercy Neuroscience Institute, Oklahoma City, OK; Malti Patel, DENT Neurologic Institute, Amherst, NY; Allan Perel, Alpha Neurology, Staten Island, NY; Joseph Phillips, Jr., Texas Neurology, PA, Dallas, TX; Mary Ann Picone, Gimbel Multiple Sclerosis Center, Holy Name Hospital, Teaneck, NJ; Kottil Rammohan, Ohio State University, Dept. of Neurology, Columbus, OH; T. Hemanth Rao, Neurological Institute, PA, Charlotte, NC; John Rinker, II, University of Alabama at Birmingham. Birmingham, AL; Saud Sadiq, Multiple Sclerosis Research Center of New York, 5New York, NY; John Schaeffer, Montana Neurosciences Institute Foundation, Missoula, MT; William Sheremata, University of Miami, Dept. of Neurology, Miami, FL; Robert Shin, University of Maryland, Maryland Center for Multiple Sclerosis, Baltimore, MD; Richard Shubin, Neuro-Therapeutics, Inc., Pasadena, CA; Stuart Silverman, Associates in Neurology of Pittsburgh, Pittsburgh, PA; Robert Smith, University of Texas Medical Branch at Galveston, Galveston; Lee Stein, Neurology Clinic, P.C., Cordova, TN; Michael Stein, Neurological Research Institute of the East Bay, Walnut Creek, CA; David Steiner, Five Towns Neuroscience Research, Cedarhurst, NY; Brian Steingo, Neurological Associates, Pompano Beach, FL; Herman Sullivan, Michigan Medical P.C., Neurology, Grand Rapids, MI; William Sunter, Jr., MIMA-Melbourne Internal Medicine Associates, Melbourne, FL; Anand Vaishnav, Kentucky Neuroscience Research, Louisville, KY; Alberto Vasquez, Suncoast Neuroscience Associates, Inc., Saint Petersburg, FL; James Voci, Michigan Neurology Associates, PC, Clinton Township, MI; Jonathan Warach, Coastal Neurology Services, Inc., Dover, NH; Bianca Weinstock-Guttman, Buffalo General Hospital, Jacobs Neurological Institute, Buffalo, NY; Mitzi Williams, Medical College of Georgia, Augusta, GA; Sibyl E. Wray, Neurology PC., Knoxville, TNADVISORY COMMITTEERobert J. Fox, Mellen Center for Multiple Sclerosis Treatment and Research, Cleveland Clinic, Cleveland, OH; J. Theodore Phillips, Multiple Sclerosis Program, Baylor Institute for Immunology Research, Dallas, TX; Michael Hutchinson, St. Vincent’s University Hospital, Elm Park, Donnybrook, Dublin, ; Eva Havrdova, Department of Neurology, First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic; Mariko Kita, Virginia Mason Medical Center, Seattle, WA; Kate Wilson, Clinical Trial Manager, Biogen Idec; Minhua Yang, Project Statistician, Biogen Idec; Katherine T. Dawson, Medical Director, Biogen IdecDATA AND SAFETY MONITORING BOARDJack Antel (Chair), Neurology, Montreal Neurological Hospital, Montreal, Quebec, Canada; James Ware (Statistics), Harvard School of Public Health, Boston, MA; Chris Polman, Neurology, VU Medical Centre, Amsterdam, The Netherlands; Peter R. Kowey, Cardiology, Jefferson Medical College, Wynnewood, PA; Raymond Chung, Hepatology, Massachusetts General Hospital, Boston, MA; George Bakris, Nephrology, University of Chicago, Pritzker School of Medicine, Chicago, IL; John Richert, Neurology, National Multiple Sclerosis Society, New York, NY, (until March 2010); Burt Seibert Independent Statistician, Statistical Services Network, Plaistow, NYINDEPENDENT NEUROLOGY EVALUATION COMMITTEE (INEC)David Brandes, Northridge Multiple Sclerosis Center, Northridge, CA; David Brassat, INSERM U.563, H?pital Purpan, Toulouse, France; Bruce Cohen, Fineberg School of Medicine, Chicago, IL; Ricarda Diem, University of the Saarland, Homburg/Saar; Myla Goldman, University of Virginia, Charlottesville, VA; Robert Herndon, University of Mississippi Medical Center, Jackson, MS; Aaron Miller, Mount Sinai Medical Center, New York, NY; Hayrettin Tumani, University of Ulm, UlmMAGNETIC RESONANCE IMAGING (MRI) CENTRAL ANALYSIS CENTERTeresa Alfaro-Vidal; Carolina Crespo; Jo Foster, Kelvin Hunter; Almudena Garcia-Gomez; David MacManus; David Miller; Virginia Santana; Dan Tozer; Claudia Kingshott-Wheeler; Tarek YousryAll: NMR Research Unit Trials Office, UCL Institute of Neurology, Queen Square, London, UK ................
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