Drug-Induced Oral Reactions
Drug-Induced Oral Reactions
A Reference Guide for Staff
?2010 PK Reviews
? Copyright 2010 PK Reviews
All Rights Reserved. Without limiting the rights under copyright reserved above, no part of this publication may be reproduced, stored in or introduced into a retrieval system, or transmitted, in any form or by any means (electronic, mechanical, photocopying, recording or otherwise), without the written permission of the copyright holder. This resource reflects the current state of knowledge about drug induced oral reactions. Every effort has been taken to ensure the information it contains is accurate and up to date. However, you should be aware that current knowledge regarding could be modified in the future to reflect changes in knowledge. While the advice, opinion and information is professionally sourced and provided in good faith and whilst all care has been taken i n the preparation of this manual, no legal liability or responsibility related to this manual and the information it contains is accepted as PK Reviews has no control over the use of the information supplied.
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Drug Induced Oral Reactions Introduction
In March 2009 the Minister for Ageing, the Hon Justine Elliot, announced Australia's first Nursing Home Oral and Dental Health Plan (The Plan). The scope of the Plan is designed to strengthen dental and oral health care in aged care homes from the initial ACAT assessment through to oral health care planning and management.
One aspect of the Plan is the Better Oral Health in Residential Care Training project which commenced in December 2009 and will continue throughout 2010.
In addition to this increased awareness of oral hygiene issues in the elderly, staff will also benefit from increased awareness of the various types of oral side effects that may occur as a result of medication use in this age group.
This resource is designed to complement the material provided by the Department of Health and Ageing and act as a resource for staff to identify possible medication related causes of oral symptoms in residents.
Every medication can produce untoward consequences even when used appropriately. Adverse drug reactions can involve any organ and system of the body including the mouth and are frequently mistaken for signs of underlying
disease.
Pharmacist medication review is a vital component of maintaining oral health in the elderly
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Drug-Induced Oral Reactions
Contents
Xerostomia
4
Sialorrhoea
5
Ageusia
6
Dysgeusia
7
Oral Thrush
8
Gingival Hyperplasia
9
Glossitis
10
Burning Mouth Syndrome
11
Oral Ulcers
12
Black Hairy Tongue
13
Stomatitis - Fixed Drug Eruption
14
- Contact Allergy
Angular Cheilitis
15
Effects on Dental Structure
16
Oral Motor Disorders
17
References used in this document:-
1. Current opinion on drug-induced oral reactions: a comprehensive review. J Contemp Dent Pract. 2008 Mar 1;9(3):1-15.
2. Osteonecrosis of the jaw with bisphosphonates. AUSTRALIAN ADVERSE DRUG REACTIONS BULLETIN Volume 25, Number 4, August 2006
3. Better Oral Health in Residential Care Facilitator Portfolio, Education and Training Program Department of Health & Ageing, Australian Government
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Xerostomia
(dry mouth)
Signs & Symptoms: Difficulty eating and swallowing Difficulty speaking Little saliva present in the mouth or may be thick stringy saliva
Antihistamines Benzodiazepines Betablockers (Atenolol, Propranolol) Calcium Channel Blockers Ciprofloxacin Clonidine Diuretics (Frusemide, Hydrochlorothiazide) Duloxetine
Ipratropium Levodopa Lithium Olanzapine Opioids (Morphine, Oxycodone) Oxybutynin Prazosin Pregabalin Propantheline Proton Pump Inhibitors Risedronate SSRIs (Sertraline, Paroxetine, Citalopram) Tricyclic antidepressants Venlafaxine Tiotropium
Phenergan Valium, Temaze Tenormin, Inderal Isoptin Ciproxin, Ciprol Catapres
Cymbalta Atrovent, Ipratrin Sinemet
Zyprexa
Ditropan Minipress Lyrica Pro-banthine Losec, Acimax, Somac, Zoton Actonel Zoloft, Aropax, Cipramil Endep Efexor Spiriva
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